Ionis Pharmaceuticals (IONS) Operating Expenses (2009 - 2026)
Ionis Pharmaceuticals (IONS) posted quarterly Operating Expenses of $370.2 million for Q2 2026, up 18.58% year-over-year from $312.2 million in Q2 2025, and up 1.85% quarter-over-quarter from $363.5 million in Q1 2026.
Ionis Pharmaceuticals (IONS) Operating Expenses (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Operating Expenses history runs 18 years deep, the most recent figure standing at $370.2 million for Q2 2026.
- In Q2 2026, Operating Expenses rose 18.58% year-over-year to $370.2 million; the TTM figure through Jun 2026 stood at $1.5 billion (up 21.3% YoY), while the FY2025 annual figure was $1.3 billion, up 12.3% from the prior year.
- Operating Expenses for Q2 2026 stood at $370.2 million, up from $363.5 million in the prior quarter.
- The five-year high for Operating Expenses was $417.8 million in Q4 2025, with the low at $199.4 million in Q1 2022.
- The 5-year median for Operating Expenses is $289.4 million (2023), against an average of $298.8 million.
- The sharpest annual moves came in 2022 and 2023: Operating Expenses soared 64.04% in 2022, then fell 8.14% in 2023.
- Ionis Pharmaceuticals' Operating Expenses stood at $359.9 million in 2022, then declined by 8.14% to $330.6 million in 2023, then gained by 2.05% to $337.4 million in 2024, then gained by 23.83% to $417.8 million in 2025, then fell by 11.38% to $370.2 million in 2026.
- Business Quant data shows IONS's Operating Expenses at $370.2 million in Q2 2026, $363.5 million in Q1 2026, and $417.8 million in Q4 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Ionis Pharmaceuticals | 9.48 Bn | 7.43 Bn | 265.21 Mn | 370.24 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 370.24 Mn |
| Mar 31, 2026 | 363.52 Mn |
| Dec 31, 2025 | 417.79 Mn |
| Sep 30, 2025 | 316.90 Mn |
| Jun 30, 2025 | 312.23 Mn |
| Mar 31, 2025 | 278.47 Mn |
| Dec 31, 2024 | 337.40 Mn |
| Sep 30, 2024 | 282.47 Mn |
| Jun 30, 2024 | 291.34 Mn |
| Mar 31, 2024 | 269.01 Mn |
| Dec 31, 2023 | 330.63 Mn |
| Sep 30, 2023 | 287.47 Mn |
| Jun 30, 2023 | 278.61 Mn |
| Mar 31, 2023 | 244.67 Mn |
| Dec 31, 2022 | 359.91 Mn |
| Sep 30, 2022 | 218.92 Mn |
| Jun 30, 2022 | 219.31 Mn |
| Mar 31, 2022 | 199.42 Mn |
| Dec 31, 2021 | 219.40 Mn |
| Sep 30, 2021 | 218.94 Mn |