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Ionis Pharmaceuticals (IONS) Operating Expenses (2016 - 2025)

Ionis Pharmaceuticals has reported Operating Expenses over the past 17 years, most recently at $417.8 million for Q4 2025.

  • Quarterly results put Operating Expenses at $417.8 million for Q4 2025, up 23.83% from a year ago — trailing twelve months through Dec 2025 was $1.3 billion (up 12.3% YoY), and the annual figure for FY2025 was $1.3 billion, up 12.3%.
  • Operating Expenses for Q4 2025 was $417.8 million at Ionis Pharmaceuticals, up from $316.9 million in the prior quarter.
  • Over the last five years, Operating Expenses for IONS hit a ceiling of $417.8 million in Q4 2025 and a floor of $198.7 million in Q2 2021.
  • Median Operating Expenses over the past 5 years was $278.5 million (2023), compared with a mean of $274.3 million.
  • Biggest five-year swings in Operating Expenses: decreased 29.89% in 2021 and later soared 64.04% in 2022.
  • Ionis Pharmaceuticals' Operating Expenses stood at $219.4 million in 2021, then skyrocketed by 64.04% to $359.9 million in 2022, then dropped by 8.14% to $330.6 million in 2023, then rose by 2.05% to $337.4 million in 2024, then rose by 23.83% to $417.8 million in 2025.
  • The last three reported values for Operating Expenses were $417.8 million (Q4 2025), $316.9 million (Q3 2025), and $312.2 million (Q2 2025) per Business Quant data.