Insmed (INSM) Operating Expenses (2010 - 2026)

Insmed (INSM) recorded quarterly Operating Expenses of $459.3 million in Q1 2026, down 21.3% quarter-over-quarter from $583.6 million in Q4 2025, and up 34.7% on a YoY basis from $341.0 million in Q1 2025.

Insmed (INSM) Operating Expenses (2010 - 2026) Analysis & Trends

Insmed's Operating Expenses history runs 17 years deep, the most recent figure standing at $459.3 million for Q1 2026.

  • In Q1 2026, Operating Expenses rose 34.7% year-over-year to $459.3 million; the TTM figure through Mar 2026 stood at $2.0 billion (up 44.76% YoY), while the FY2025 annual figure was $1.9 billion, up 49.22% from the prior year.
  • Operating Expenses was $459.3 million for Q1 2026 at Insmed, down from $583.6 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $583.6 million in Q4 2025 to a low of $142.9 million in Q1 2022.
  • Historically, Operating Expenses has averaged $310.1 million across 5 years, with a median of $306.9 million in 2024.
  • The sharpest annual moves came in 2023 and 2024: Operating Expenses jumped 103.7% in 2023, then grew 3.58% in 2024.
  • A 5-year view of Operating Expenses shows it stood at $210.8 million in 2022, then advanced by 24.29% to $262.0 million in 2023, then advanced by 27.82% to $334.9 million in 2024, then jumped by 74.28% to $583.6 million in 2025, then declined by 21.3% to $459.3 million in 2026.
  • The last three Operating Expenses figures came in at $459.3 million (Q1 2026), $583.6 million (Q4 2025), and $508.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 4.33 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 2.97 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 15.76 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.82 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 574,669.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.71 Bn 91.71 Bn - -67.40 Mn
10 Insmed 19.79 Bn 18.57 Bn 258.54 Mn 459.28 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 459.28 Mn
Dec 31, 2025 583.59 Mn
Sep 30, 2025 508.35 Mn
Jun 30, 2025 420.29 Mn
Mar 31, 2025 340.96 Mn
Dec 31, 2024 334.86 Mn
Sep 30, 2024 306.85 Mn
Jun 30, 2024 379.24 Mn
Mar 31, 2024 221.01 Mn
Dec 31, 2023 261.97 Mn
Sep 30, 2023 226.74 Mn
Jun 30, 2023 312.76 Mn
Mar 31, 2023 213.37 Mn
Dec 31, 2022 210.78 Mn
Sep 30, 2022 195.43 Mn
Jun 30, 2022 153.54 Mn
Mar 31, 2022 142.94 Mn
Dec 31, 2021 155.20 Mn
Sep 30, 2021 150.37 Mn
Jun 30, 2021 133.93 Mn