Insmed (INSM) Operating Expenses (2010 - 2026)

Insmed's (INSM) quarterly Operating Expenses came in at $459.3 million in Q1 2026, up 34.7% year-on-year from $341.0 million in Q1 2025, and down 21.3% quarter-over-quarter from $583.6 million in Q4 2025.

Insmed (INSM) Operating Expenses (2010 - 2026) Analysis & Trends

Insmed's Operating Expenses history runs 17 years deep, the most recent figure standing at $459.3 million for Q1 2026.

  • On a quarterly basis, Operating Expenses rose 34.7% year-over-year to $459.3 million in Q1 2026; TTM through Mar 2026 was $2.0 billion, a 44.76% increase from a year earlier, with the FY2025 full-year figure at $1.9 billion, up 49.22% from the prior year.
  • Operating Expenses retreated to $459.3 million in Q1 2026 per INSM's latest filing, from $583.6 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $583.6 million in Q4 2025 and bottomed at $142.9 million in Q1 2022.
  • The 5-year median for Operating Expenses is $306.9 million (2024), against an average of $310.1 million.
  • Across the five-year window, Operating Expenses soared 103.7% in 2023 and rose 3.58% in 2024, its largest moves.
  • Year by year, Operating Expenses stood at $210.8 million in 2022, then advanced by 24.29% to $262.0 million in 2023, then advanced by 27.82% to $334.9 million in 2024, then jumped by 74.28% to $583.6 million in 2025, then declined by 21.3% to $459.3 million in 2026.
  • Per Business Quant, the three latest INSM Operating Expenses figures stand at $459.3 million (Q1 2026), $583.6 million (Q4 2025), and $508.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Insmed 23.02 Bn 21.80 Bn 258.54 Mn 459.28 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 459.28 Mn
Dec 31, 2025 583.59 Mn
Sep 30, 2025 508.35 Mn
Jun 30, 2025 420.29 Mn
Mar 31, 2025 340.96 Mn
Dec 31, 2024 334.86 Mn
Sep 30, 2024 306.85 Mn
Jun 30, 2024 379.24 Mn
Mar 31, 2024 221.01 Mn
Dec 31, 2023 261.97 Mn
Sep 30, 2023 226.74 Mn
Jun 30, 2023 312.76 Mn
Mar 31, 2023 213.37 Mn
Dec 31, 2022 210.78 Mn
Sep 30, 2022 195.43 Mn
Jun 30, 2022 153.54 Mn
Mar 31, 2022 142.94 Mn
Dec 31, 2021 155.20 Mn
Sep 30, 2021 150.37 Mn
Jun 30, 2021 133.93 Mn