Insmed (INSM) Operating Expenses (2010 - 2026)
Insmed's (INSM) quarterly Operating Expenses came in at $459.3 million in Q1 2026, up 34.7% year-on-year from $341.0 million in Q1 2025, and down 21.3% quarter-over-quarter from $583.6 million in Q4 2025.
Insmed (INSM) Operating Expenses (2010 - 2026) Analysis & Trends
Insmed's Operating Expenses history runs 17 years deep, the most recent figure standing at $459.3 million for Q1 2026.
- On a quarterly basis, Operating Expenses rose 34.7% year-over-year to $459.3 million in Q1 2026; TTM through Mar 2026 was $2.0 billion, a 44.76% increase from a year earlier, with the FY2025 full-year figure at $1.9 billion, up 49.22% from the prior year.
- Operating Expenses retreated to $459.3 million in Q1 2026 per INSM's latest filing, from $583.6 million in the prior quarter.
- Across five years, Operating Expenses topped out at $583.6 million in Q4 2025 and bottomed at $142.9 million in Q1 2022.
- The 5-year median for Operating Expenses is $306.9 million (2024), against an average of $310.1 million.
- Across the five-year window, Operating Expenses soared 103.7% in 2023 and rose 3.58% in 2024, its largest moves.
- Year by year, Operating Expenses stood at $210.8 million in 2022, then advanced by 24.29% to $262.0 million in 2023, then advanced by 27.82% to $334.9 million in 2024, then jumped by 74.28% to $583.6 million in 2025, then declined by 21.3% to $459.3 million in 2026.
- Per Business Quant, the three latest INSM Operating Expenses figures stand at $459.3 million (Q1 2026), $583.6 million (Q4 2025), and $508.3 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | Insmed | 23.02 Bn | 21.80 Bn | 258.54 Mn | 459.28 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 459.28 Mn |
| Dec 31, 2025 | 583.59 Mn |
| Sep 30, 2025 | 508.35 Mn |
| Jun 30, 2025 | 420.29 Mn |
| Mar 31, 2025 | 340.96 Mn |
| Dec 31, 2024 | 334.86 Mn |
| Sep 30, 2024 | 306.85 Mn |
| Jun 30, 2024 | 379.24 Mn |
| Mar 31, 2024 | 221.01 Mn |
| Dec 31, 2023 | 261.97 Mn |
| Sep 30, 2023 | 226.74 Mn |
| Jun 30, 2023 | 312.76 Mn |
| Mar 31, 2023 | 213.37 Mn |
| Dec 31, 2022 | 210.78 Mn |
| Sep 30, 2022 | 195.43 Mn |
| Jun 30, 2022 | 153.54 Mn |
| Mar 31, 2022 | 142.94 Mn |
| Dec 31, 2021 | 155.20 Mn |
| Sep 30, 2021 | 150.37 Mn |
| Jun 30, 2021 | 133.93 Mn |