Immatics (IMTX) Operating Expenses (2019 - 2025)

Immatics recorded quarterly Operating Expenses of -$73.7 million in Q4 2025, down 5.32% quarter-over-quarter from -$70.0 million in Q3 2025, and down 24.54% year-over-year from -$97.7 million in Q4 2024.

Immatics' Operating Expenses history runs 7 years deep, the most recent figure standing at -$73.7 million for Q4 2025.

  • In Q4 2025, Operating Expenses fell 24.54% year-over-year to -$73.7 million; the TTM figure through Dec 2025 stood at -$266.0 million (down 26.34% YoY), while the FY2025 annual figure was -$265.5 million, down 27.73% from the prior year.
  • Operating Expenses came in at -$73.7 million for Q4 2025 at Immatics, down from -$70.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of -$34.5 million in Q2 2021 to a low of -$73.7 million in Q4 2025.
  • A 5-year average of -$47.0 million and a median of -$41.4 million in 2023 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses tumbled 86.6% in 2021 and declined 1.74% in 2022, its largest moves.
  • Immatics' Operating Expenses stood at -$36.4 million in 2021, then declined by 5.41% to -$38.3 million in 2022, then dropped by 22.44% to -$47.0 million in 2023, then slipped by 26.02% to -$59.2 million in 2024, then fell by 24.54% to -$73.7 million in 2025.
  • According to Business Quant data, Operating Expenses over the past three periods registered -$73.7 million, -$70.0 million, and -$65.5 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 2.97 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - 4.33 Mn
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 898.54 Mn
10 Immatics 1.80 Bn 1.80 Bn - -73.69 Mn

Historic Data

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DateValue
Dec 31, 2025 -73.69 Mn
Sep 30, 2025 -69.97 Mn
Jun 30, 2025 -65.52 Mn
Mar 31, 2025 -56.78 Mn
Dec 31, 2024 -59.17 Mn
Sep 30, 2024 -54.98 Mn
Jun 30, 2024 -48.83 Mn
Mar 31, 2024 -47.53 Mn
Dec 31, 2023 -46.95 Mn
Sep 30, 2023 -42.87 Mn
Jun 30, 2023 -39.94 Mn
Mar 31, 2023 -39.89 Mn
Dec 31, 2022 -38.35 Mn
Sep 30, 2022 -37.30 Mn
Jun 30, 2022 -36.17 Mn
Mar 31, 2022 -38.63 Mn
Dec 31, 2021 -36.38 Mn
Sep 30, 2021 -34.78 Mn
Jun 30, 2021 -34.46 Mn
Mar 31, 2021 -37.97 Mn
Dec 31, 2020 -35.23 Mn
Sep 30, 2020 -31.19 Mn
Jun 30, 2020 -29.28 Mn
Mar 31, 2020 -20.35 Mn
Dec 31, 2019 -18.52 Mn
Sep 30, 2019 -14.47 Mn
Jun 30, 2019 -13.31 Mn