Humacyte (HUMA) Return on Capital Employed (2021 - 2026)

Humacyte (HUMA) reported Return on Capital Employed of 117.08% for Q1 2026, down 3179.0% year-over-year from 3.8% in Q1 2025, and up 7.37% quarter-over-quarter from 126.4% in Q4 2025.

Humacyte (HUMA) Return on Capital Employed (2021 - 2026) Analysis & Trends

Humacyte (HUMA) has 6 years of Return on Capital Employed data on file, last reported at 117.08% in Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 117.08%, down 3179.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 117.08% (down 3179.0% YoY), and the FY2025 annual result was 99.44%, up 172.0% from the prior year.
  • Return on Capital Employed advanced to 117.08% in Q1 2026 per HUMA's latest filing, from 126.4% in the prior quarter.
  • Over five years, Return on Capital Employed peaked at 31.43% in Q1 2022 and troughed at 126.4% in Q4 2025.
  • A 5-year average of 77.1% and a median of 80.9% in 2024 frame the typical range for Return on Capital Employed.
  • The sharpest annual moves came in 2022 and 2024: Return on Capital Employed soared 2255 bps in 2022, then plunged 4062 bps in 2024.
  • A 5-year view of Return on Capital Employed shows it stood at 43.23% in 2022, then tumbled by 92 bps to 83.12% in 2023, then retreated by 29 bps to 107.56% in 2024, then decreased by 18 bps to 126.4% in 2025, then climbed by 7 bps to 117.08% in 2026.
  • Business Quant data shows HUMA's Return on Capital Employed at 117.08% in Q1 2026, 126.4% in Q4 2025, and 117.69% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Humacyte 183.21 Mn 134.67 Mn -1.54 Mn -117.08%

Historic Data

Download Data
DateValue
Mar 31, 2026 -117.08%
Dec 31, 2025 -126.40%
Sep 30, 2025 -117.69%
Jun 30, 2025 -85.86%
Mar 31, 2025 -85.29%
Dec 31, 2024 -107.56%
Sep 30, 2024 -106.55%
Jun 30, 2024 -80.90%
Mar 31, 2024 -79.62%
Dec 31, 2023 -83.12%
Sep 30, 2023 -65.93%
Jun 30, 2023 -56.99%
Mar 31, 2023 -50.19%
Dec 31, 2022 -43.23%
Sep 30, 2022 -39.11%
Jun 30, 2022 -33.75%
Mar 31, 2022 -31.43%
Dec 31, 2021 -28.60%
Sep 30, 2021 -33.11%
Jun 30, 2021 -56.29%