As of September 29, 2026, the three largest insider holders of HUMA are Llc Ayabudge (TenPercentOwner, 8.19Mn shares), Brady W Dougan (Director, 510.16K shares), Laura E Niklason (President, Ceo And Director, 510.16K shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Llc Ayabudge | TenPercentOwner | 8,191,140 | 0 | 8,191,140 | 84.4% | 21 Aug, 2023 |
| 2 | Shamik J Parikh | Chief Medical Officer | 272,713 | 0 | 272,713 | 2.8% | 20 May, 2026 |
| 3 | Dale A. Sander | Cfo And Chief Corp. Dev. Off | 267,213 | 0 | 267,213 | 2.8% | 20 May, 2026 |
| 4 | Laura E Niklason | President, Ceo And Director | 243,851 | 0 | 243,851 | 2.5% | 21 Nov, 2024 |
| 5 | Brady W Dougan | Director | 0 | 243,851 | 243,851 | 2.5% | 21 Nov, 2024 |
| 6 | Gordon M Binder | Director | 160,000 | 50,000 | 210,000 | 2.2% | 15 May, 2024 |
| 7 | Kathleen Sebelius | Director | 148,025 | 0 | 148,025 | 1.5% | 20 May, 2026 |
| 8 | Keith Anthony Jones | Director | 50,000 | 0 | 50,000 | 0.5% | 15 Sep, 2026 |
| 9 | Michael T. Constantino | Director | 43,950 | 0 | 43,950 | 0.5% | 20 May, 2026 |
| 10 | William John Scheessele | Chief Commercial Officer | 22,018 | 0 | 22,018 | 0.2% | 15 Apr, 2025 |
| 11 | Charles Bruce Green | Director | 8,400 | 0 | 8,400 | 0.1% | 08 Apr, 2025 |
| 12 | Max N. Wallace | Director | 0 | 8,005 | 8,005 | 0.1% | 21 May, 2024 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 20 Aug, 2026 | Keith Anthony Jones | Director | Acquired P | 10,000 | $0.69 | $6.93K | 40,000 | Direct |
| 17 Aug, 2026 | Keith Anthony Jones | Director | Acquired P | 30,000 | $0.59 | $17.82K | 30,000 | Direct |
| 11 Jun, 2026 | Kathleen Sebelius | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Charles Bruce Green | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Diane Seimetz | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Susan Richards Windham-Bannister | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Emery N. Brown | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Michael T. Constantino | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Laura E Niklason | President, Ceo And Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Indirect |
| 11 Jun, 2026 | John Philip Bamforth | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Max N. Wallace | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 11 Jun, 2026 | Keith Anthony Jones | Director | Acquired A | 80,000 | $0.00 | $0 | 80,000 | Direct |
| 18 May, 2026 | Dale A. Sander | Cfo And Chief Corp. Dev. Off | Disposed S | 45,887 | $0.90 | $41.15K | 267,213 | Direct |
| 18 May, 2026 | Michael T. Constantino | Director | Acquired P | 11,000 | $0.89 | $9.84K | 43,950 | Direct |
| 19 May, 2026 | Kathleen Sebelius | Director | Acquired P | 56,818 | $0.88 | $50.00K | 148,025 | Direct |
| 18 May, 2026 | Shamik J Parikh | Chief Medical Officer | Disposed S | 45,887 | $0.90 | $41.15K | 272,713 | Direct |
| 16 Nov, 2025 | Brady W Dougan | Director | Acquired A | 311,100 | $0.00 | $0 | 311,100 | Indirect |
| 16 Nov, 2025 | Shamik J Parikh | Chief Medical Officer | Acquired A | 311,100 | $0.00 | $0 | 318,600 | Direct |
| 16 Nov, 2025 | Dale A. Sander | Cfo And Chief Corp. Deve. Off. | Acquired A | 311,100 | $0.00 | $0 | 313,100 | Direct |
| 16 Nov, 2025 | Laura E Niklason | President, Ceo And Director | Acquired A | 311,100 | $0.00 | $0 | 311,100 | Direct |