Grail (GRAL) Operating Margin (2023 - 2026)
Grail (GRAL) reported Operating Margin of 332.88% for Q1 2026, up 14960.0% on a YoY basis from N/an in Q1 2025, and down 16.65% quarter-over-quarter from 285.37% in Q4 2025.
Grail (GRAL) Operating Margin (2023 - 2026) Analysis & Trends
Grail has reported Operating Margin for 4 years, with the latest figure at 332.88% in Q1 2026.
- For the quarter ending Q1 2026, Operating Margin rose 14960.0% year-over-year to 332.88%; the trailing twelve-month figure through Mar 2026 stood at 348.66% (up 126968.0% YoY), and the FY2025 full-year result was 381.98%, up 136105.0% from the prior year.
- Operating Margin for Q1 2026 stood at 332.88%, down from 285.37% in the prior quarter.
- The five-year high for Operating Margin was 210.2% in Q4 2023, with the low at 5133.85% in Q2 2024.
- Historically, Operating Margin has averaged 1200.18% across 4 years, with a median of 464.7% in 2025.
- Annual changes were most pronounced in 2024 — Operating Margin sank 422206 bps — and 2025, when it surged 468693 bps.
- Grail's Operating Margin stood at 210.2% in 2023, then plunged by 70 bps to 357.99% in 2024, then gained by 20 bps to 285.37% in 2025, then fell by 17 bps to 332.88% in 2026.
- The last three Operating Margin figures came in at 332.88% (Q1 2026), 285.37% (Q4 2025), and 346.17% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | -3.71% |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 16.93% |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 22.58% |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 31.78% |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 21.74% |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 12.38% |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | -13.42% |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 19.16% |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 25.23% |
| 10 | Grail | 2.49 Bn | 2.49 Bn | 10.12 Mn | -332.88% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -332.88% |
| Dec 31, 2025 | -285.37% |
| Sep 30, 2025 | -346.17% |
| Jun 30, 2025 | -446.92% |
| Mar 31, 2025 | -482.48% |
| Dec 31, 2024 | -357.99% |
| Sep 30, 2024 | -640.47% |
| Jun 30, 2024 | -5,133.85% |
| Mar 31, 2024 | -851.10% |
| Dec 31, 2023 | -210.20% |
| Oct 1, 2023 | -4,403.01% |
| Jun 30, 2023 | -911.78% |