Grail (GRAL) Operating Margin (2023 - 2026)
Grail's (GRAL) quarterly Operating Margin came in at 332.88% in Q1 2026, up 14960.0% YoY from N/an in Q1 2025, and down 16.65% on a QoQ basis from 285.37% in Q4 2025.
Grail (GRAL) Operating Margin (2023 - 2026) Analysis & Trends
Grail (GRAL) has 4 years of Operating Margin data on file, last reported at 332.88% in Q1 2026.
- Quarterly Operating Margin rose 14960.0% year-over-year to 332.88% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 348.66% (up 126968.0% YoY) and the FY2025 annual result came in at 381.98%, up 136105.0% from the prior year.
- Operating Margin slipped to 332.88% in Q1 2026, from 285.37% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 210.2% in Q4 2023 to a low of 5133.85% in Q2 2024.
- A 4-year average of 1200.18% and a median of 464.7% in 2025 frame the typical range for Operating Margin.
- Annual changes were most pronounced in 2024 — Operating Margin sank 422206 bps — and 2025, when it surged 468693 bps.
- Tracing GRAL's Operating Margin over 4 years: stood at 210.2% in 2023, then plunged by 70 bps to 357.99% in 2024, then gained by 20 bps to 285.37% in 2025, then fell by 17 bps to 332.88% in 2026.
- The last three Operating Margin figures came in at 332.88% (Q1 2026), 285.37% (Q4 2025), and 346.17% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.88 Bn | 209.81 Bn | 8.34 Bn | 17.40% |
| 2 | Danaher | 140.65 Bn | 136.30 Bn | 3.61 Bn | 17.99% |
| 3 | Idexx Laboratories | 46.02 Bn | 45.83 Bn | 779.09 Mn | 34.98% |
| 4 | Agilent Technologies | 39.85 Bn | 38.05 Bn | 990.00 Mn | 21.74% |
| 5 | Iqvia Holdings | 39.20 Bn | 37.12 Bn | 1.44 Bn | 11.58% |
| 6 | Natera | 38.80 Bn | 37.70 Bn | 696.04 Mn | -13.42% |
| 7 | Illumina | 30.11 Bn | 28.94 Bn | 770.00 Mn | 21.14% |
| 8 | Mettler Toledo International | 28.66 Bn | 28.61 Bn | 650.22 Mn | 31.97% |
| 9 | Quest Diagnostics | 26.24 Bn | 25.61 Bn | 1.03 Bn | 15.08% |
| 10 | Grail | 3.01 Bn | 2.19 Bn | 19.54 Mn | -332.88% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -332.88% |
| Dec 31, 2025 | -285.37% |
| Sep 30, 2025 | -346.17% |
| Jun 30, 2025 | -446.92% |
| Mar 31, 2025 | -482.48% |
| Dec 31, 2024 | -357.99% |
| Sep 30, 2024 | -640.47% |
| Jun 30, 2024 | -5,133.85% |
| Mar 31, 2024 | -851.10% |
| Dec 31, 2023 | -210.20% |
| Oct 1, 2023 | -4,403.01% |
| Jun 30, 2023 | -911.78% |