Growth Metrics

Natera (NTRA) Operating Margin (2016 - 2026)

Natera filings provide 12 years of Operating Margin readings, the most recent being 3.42% for Q4 2025.

  • On a quarterly basis, Operating Margin fell 2815.0% to 3.42% in Q4 2025 year-over-year; TTM through Dec 2025 was 13.44%, a 1109.0% decrease, with the full-year FY2025 number at 13.44%, down 1109.0% from a year prior.
  • Operating Margin hit 3.42% in Q4 2025 for Natera, up from 16.48% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 86.93% in Q4 2023 to a low of 94.99% in Q3 2021.
  • Median Operating Margin over the past 5 years was 41.37% (2023), compared with a mean of 34.42%.
  • Biggest five-year swings in Operating Margin: soared 15219bps in 2023 and later crashed -6221bps in 2024.
  • Natera's Operating Margin stood at 80.72% in 2021, then rose by 19bps to 65.26% in 2022, then skyrocketed by 233bps to 86.93% in 2023, then plummeted by -72bps to 24.73% in 2024, then tumbled by -114bps to 3.42% in 2025.
  • The last three reported values for Operating Margin were 3.42% (Q4 2025), 16.48% (Q3 2025), and 20.19% (Q2 2025) per Business Quant data.