Natera (NTRA) Operating Margin (2014 - 2026)

Natera's (NTRA) quarterly Operating Margin came in at 13.42% in Q1 2026, up 235.0% YoY from 4.01% in Q1 2025, and down 292.08% on a QoQ basis from 3.42% in Q4 2025.

Natera (NTRA) Operating Margin (2014 - 2026) Analysis & Trends

Natera (NTRA) has 13 years of Operating Margin data on file, last reported at 13.42% in Q1 2026.

  • Quarterly Operating Margin rose 235.0% year-over-year to 13.42% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 12.97% (down 56.0% YoY) and the FY2025 annual result came in at 13.44%, down 34.0% from the prior year.
  • Operating Margin declined to 13.42% in Q1 2026, from 3.42% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 3.42% in Q4 2025 to a low of 72.19% in Q2 2022.
  • A 5-year average of 32.71% and a median of 20.21% in 2024 frame the typical range for Operating Margin.
  • The widest YoY moves for Operating Margin: up 3847 bps in 2022, down 2926 bps in 2022.
  • Tracing NTRA's Operating Margin over 5 years: stood at 65.26% in 2022, then soared by 58 bps to 27.17% in 2023, then jumped by 50 bps to 13.6% in 2024, then surged by 75 bps to 3.42% in 2025, then slumped by 292 bps to 13.42% in 2026.
  • The last three Operating Margin figures came in at 13.42% (Q1 2026), 3.42% (Q4 2025), and 16.48% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Thermo Fisher Scientific 213.88 Bn 209.81 Bn 8.34 Bn 17.40%
2 Danaher 140.65 Bn 136.30 Bn 3.61 Bn 17.99%
3 Idexx Laboratories 46.02 Bn 45.83 Bn 779.09 Mn 34.98%
4 Agilent Technologies 39.85 Bn 38.05 Bn 990.00 Mn 21.74%
5 Iqvia Holdings 39.20 Bn 37.12 Bn 1.44 Bn 11.58%
6 Natera 38.80 Bn 37.70 Bn 696.04 Mn -13.42%
7 Illumina 30.11 Bn 28.94 Bn 770.00 Mn 21.14%
8 Mettler Toledo International 28.66 Bn 28.61 Bn 650.22 Mn 31.97%
9 Quest Diagnostics 26.24 Bn 25.61 Bn 1.03 Bn 15.08%
10 Labcorp Holdings 25.87 Bn 24.89 Bn 1.01 Bn 10.76%

Historic Data

Download Data
DateValue
Mar 31, 2026 -13.42%
Dec 31, 2025 -3.42%
Sep 30, 2025 -16.48%
Jun 30, 2025 -20.19%
Mar 31, 2025 -15.78%
Dec 31, 2024 -13.60%
Sep 30, 2024 -8.95%
Jun 30, 2024 -10.62%
Mar 31, 2024 -20.21%
Dec 31, 2023 -27.17%
Sep 30, 2023 -41.36%
Jun 30, 2023 -43.01%
Mar 31, 2023 -57.21%
Dec 31, 2022 -65.26%
Sep 30, 2022 -56.52%
Jun 30, 2022 -72.19%
Mar 31, 2022 -70.64%
Dec 31, 2021 -80.72%
Sep 30, 2021 -94.99%
Jun 30, 2021 -81.18%