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Guardant Health (GH) Operating Margin: 2017-2025

Historic Operating Margin for Guardant Health (GH) over the last 8 years, with Sep 2025 value amounting to -37.33%.

  • Guardant Health's Operating Margin rose 2395.00% to -37.33% in Q3 2025 from the same period last year, while for Sep 2025 it was -49.02%, marking a year-over-year increase of 2540.00%. This contributed to the annual value of -60.02% for FY2024, which is 4011.00% up from last year.
  • As of Q3 2025, Guardant Health's Operating Margin stood at -37.33%, which was up 18.59% from -45.85% recorded in Q2 2025.
  • In the past 5 years, Guardant Health's Operating Margin ranged from a high of -37.33% in Q3 2025 and a low of -137.12% during Q1 2021.
  • Moreover, its 3-year median value for Operating Margin was -61.28% (2024), whereas its average is -70.50%.
  • Per our database at Business Quant, Guardant Health's Operating Margin tumbled by 8,540bps in 2021 and then soared by 6,497bps in 2024.
  • Over the past 5 years, Guardant Health's Operating Margin (Quarterly) stood at -90.84% in 2021, then crashed by 2,431bps to -115.15% in 2022, then slumped by 1,223bps to -127.38% in 2023, then soared by 6,497bps to -62.42% in 2024, then spiked by 2,395bps to -37.33% in 2025.
  • Its Operating Margin stands at -37.33% for Q3 2025, versus -45.85% for Q2 2025 and -54.57% for Q1 2025.