Guardant Health (GH) Operating Margin (2017 - 2026)
Guardant Health (GH) posted Operating Margin of 38.55% for Q2 2026, up 4.18% sequentially from 40.23% in Q1 2026, and up 731.0% YoY from 4.64% in Q2 2025.
Guardant Health (GH) Operating Margin (2017 - 2026) Analysis & Trends
Guardant Health has reported Operating Margin for 10 years, with the latest figure at 38.55% in Q2 2026.
- Quarterly Operating Margin rose 731.0% year-over-year to 38.55% in Q2 2026, while the trailing twelve-month figure through Jun 2026 was 39.75% (up 1584.0% YoY) and the FY2025 annual result came in at 44.53%, up 1550.0% from the prior year.
- Operating Margin grew to 38.55% in Q2 2026 per GH's latest filing, from 40.23% in the prior quarter.
- Over five years, Operating Margin peaked at 37.33% in Q3 2025 and troughed at 128.34% in Q1 2022.
- A 5-year average of 76.85% and a median of 61.85% in 2024 frame the typical range for Operating Margin.
- The sharpest annual moves came in 2022 and 2024: Operating Margin slumped 2431 bps in 2022, then surged 6497 bps in 2024.
- Over 5 years, Operating Margin stood at 115.15% in 2022, then slipped by 11 bps to 127.38% in 2023, then jumped by 51 bps to 62.42% in 2024, then soared by 31 bps to 42.95% in 2025, then rose by 10 bps to 38.55% in 2026.
- According to Business Quant data, Operating Margin over the past three periods registered 38.55%, 40.23%, and 42.95% for Q2 2026, Q1 2026, and Q4 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.88 Bn | 209.81 Bn | 8.34 Bn | 17.40% |
| 2 | Danaher | 140.65 Bn | 136.30 Bn | 3.61 Bn | 17.99% |
| 3 | Idexx Laboratories | 46.02 Bn | 45.83 Bn | 779.09 Mn | 34.98% |
| 4 | Agilent Technologies | 39.85 Bn | 38.05 Bn | 990.00 Mn | 21.74% |
| 5 | Iqvia Holdings | 39.20 Bn | 37.12 Bn | 1.44 Bn | 11.58% |
| 6 | Natera | 38.80 Bn | 37.70 Bn | 696.04 Mn | -13.42% |
| 7 | Illumina | 30.11 Bn | 28.94 Bn | 770.00 Mn | 21.14% |
| 8 | Mettler Toledo International | 28.66 Bn | 28.61 Bn | 650.22 Mn | 31.97% |
| 9 | Quest Diagnostics | 26.24 Bn | 25.61 Bn | 1.03 Bn | 15.08% |
| 10 | Guardant Health | 21.59 Bn | 20.53 Bn | 219.03 Mn | -38.55% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -38.55% |
| Mar 31, 2026 | -40.23% |
| Dec 31, 2025 | -42.95% |
| Sep 30, 2025 | -37.33% |
| Jun 30, 2025 | -45.85% |
| Mar 31, 2025 | -54.57% |
| Dec 31, 2024 | -62.42% |
| Sep 30, 2024 | -61.28% |
| Jun 30, 2024 | -56.77% |
| Mar 31, 2024 | -59.16% |
| Dec 31, 2023 | -127.38% |
| Sep 30, 2023 | -79.38% |
| Jun 30, 2023 | -87.22% |
| Mar 31, 2023 | -104.15% |
| Dec 31, 2022 | -115.15% |
| Sep 30, 2022 | -123.16% |
| Jun 30, 2022 | -119.40% |
| Mar 31, 2022 | -128.34% |
| Dec 31, 2021 | -90.84% |
| Sep 30, 2021 | -113.20% |