GH Research (GHRS) Operating Expenses (2020 - 2025)

GH Research's (GHRS) quarterly Operating Expenses came in at -$71.5 million in Q4 2025, down 7.37% year-on-year from -$77.2 million in Q4 2024, and down 1664.26% quarter-over-quarter from $4.6 million in Q3 2025.

GH Research (GHRS) Operating Expenses (2020 - 2025) Analysis & Trends

GH Research's Operating Expenses history runs 6 years deep, the most recent figure standing at -$71.5 million for Q4 2025.

  • On a quarterly basis, Operating Expenses fell 7.37% year-over-year to -$71.5 million in Q4 2025; TTM through Dec 2025 was -$60.7 million, a 20.68% decrease from a year earlier, with the FY2025 full-year figure at $60.7 million, up 20.68% from the prior year.
  • Operating Expenses slipped to -$71.5 million in Q4 2025 per GHRS's latest filing, from $4.6 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $28.1 million in Q4 2023 and bottomed at -$71.5 million in Q4 2025.
  • The 5-year median for Operating Expenses is $3.7 million (2024), against an average of -$1.7 million.
  • Biggest YoY gain for Operating Expenses was 4058.55% in 2021; the steepest drop was 7676.67% in 2021.
  • Year by year, Operating Expenses stood at $23.6 million in 2021, then rose by 5.13% to $24.8 million in 2022, then grew by 13.54% to $28.1 million in 2023, then plunged by 336.5% to -$66.6 million in 2024, then declined by 7.37% to -$71.5 million in 2025.
  • Per Business Quant, the three latest GHRS Operating Expenses figures stand at -$71.5 million (Q4 2025), $4.6 million (Q3 2025), and $3.2 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 GH Research 1.65 Bn 1.65 Bn - -71.47 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -71.47 Mn
Sep 30, 2025 4.57 Mn
Jun 30, 2025 3.21 Mn
Mar 31, 2025 2.97 Mn
Dec 31, 2024 -66.56 Mn
Sep 30, 2024 4.17 Mn
Jun 30, 2024 6.29 Mn
Mar 31, 2024 5.79 Mn
Dec 31, 2023 28.15 Mn
Sep 30, 2023 4.46 Mn
Jun 30, 2023 4.43 Mn
Mar 31, 2023 4.19 Mn
Dec 31, 2022 24.79 Mn
Sep 30, 2022 2.61 Mn
Jun 30, 2022 1.73 Mn
Mar 31, 2022 -8.01 Mn
Dec 31, 2021 23.58 Mn
Sep 30, 2021 -4.67 Mn
Jun 30, 2021 -2.67 Mn
Mar 31, 2021 -1.14 Mn