GH Research (GHRS) Operating Expenses (2020 - 2025)
GH Research (GHRS) recorded quarterly Operating Expenses of -$71.5 million in Q4 2025, down 1664.26% quarter-over-quarter from $4.6 million in Q3 2025, and down 7.37% on a YoY basis from -$77.2 million in Q4 2024.
GH Research (GHRS) Operating Expenses (2020 - 2025) Analysis & Trends
GH Research's Operating Expenses history runs 6 years deep, the most recent figure standing at -$71.5 million for Q4 2025.
- In Q4 2025, Operating Expenses fell 7.37% year-over-year to -$71.5 million; the TTM figure through Dec 2025 stood at -$60.7 million (down 20.68% YoY), while the FY2025 annual figure was $60.7 million, up 20.68% from the prior year.
- Operating Expenses was -$71.5 million for Q4 2025 at GH Research, down from $4.6 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $28.1 million in Q4 2023 to a low of -$71.5 million in Q4 2025.
- Historically, Operating Expenses has averaged -$1.7 million across 5 years, with a median of $3.7 million in 2024.
- Biggest YoY gain for Operating Expenses was 4058.55% in 2021; the steepest drop was 7676.67% in 2021.
- A 5-year view of Operating Expenses shows it stood at $23.6 million in 2021, then rose by 5.13% to $24.8 million in 2022, then grew by 13.54% to $28.1 million in 2023, then slumped by 336.5% to -$66.6 million in 2024, then declined by 7.37% to -$71.5 million in 2025.
- The last three Operating Expenses figures came in at -$71.5 million (Q4 2025), $4.6 million (Q3 2025), and $3.2 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | 15.76 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -67.40 Mn |
| 10 | GH Research | 9.73 Bn | 9.63 Bn | - | -71.47 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -71.47 Mn |
| Sep 30, 2025 | 4.57 Mn |
| Jun 30, 2025 | 3.21 Mn |
| Mar 31, 2025 | 2.97 Mn |
| Dec 31, 2024 | -66.56 Mn |
| Sep 30, 2024 | 4.17 Mn |
| Jun 30, 2024 | 6.29 Mn |
| Mar 31, 2024 | 5.79 Mn |
| Dec 31, 2023 | 28.15 Mn |
| Sep 30, 2023 | 4.46 Mn |
| Jun 30, 2023 | 4.43 Mn |
| Mar 31, 2023 | 4.19 Mn |
| Dec 31, 2022 | 24.79 Mn |
| Sep 30, 2022 | 2.61 Mn |
| Jun 30, 2022 | 1.73 Mn |
| Mar 31, 2022 | -8.01 Mn |
| Dec 31, 2021 | 23.58 Mn |
| Sep 30, 2021 | -4.67 Mn |
| Jun 30, 2021 | -2.67 Mn |
| Mar 31, 2021 | -1.14 Mn |