GH Research (GHRS) Operating Expenses (2020 - 2025)

GH Research (GHRS) recorded quarterly Operating Expenses of -$71.5 million in Q4 2025, down 1664.26% quarter-over-quarter from $4.6 million in Q3 2025, and down 7.37% on a YoY basis from -$77.2 million in Q4 2024.

GH Research (GHRS) Operating Expenses (2020 - 2025) Analysis & Trends

GH Research's Operating Expenses history runs 6 years deep, the most recent figure standing at -$71.5 million for Q4 2025.

  • In Q4 2025, Operating Expenses fell 7.37% year-over-year to -$71.5 million; the TTM figure through Dec 2025 stood at -$60.7 million (down 20.68% YoY), while the FY2025 annual figure was $60.7 million, up 20.68% from the prior year.
  • Operating Expenses was -$71.5 million for Q4 2025 at GH Research, down from $4.6 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $28.1 million in Q4 2023 to a low of -$71.5 million in Q4 2025.
  • Historically, Operating Expenses has averaged -$1.7 million across 5 years, with a median of $3.7 million in 2024.
  • Biggest YoY gain for Operating Expenses was 4058.55% in 2021; the steepest drop was 7676.67% in 2021.
  • A 5-year view of Operating Expenses shows it stood at $23.6 million in 2021, then rose by 5.13% to $24.8 million in 2022, then grew by 13.54% to $28.1 million in 2023, then slumped by 336.5% to -$66.6 million in 2024, then declined by 7.37% to -$71.5 million in 2025.
  • The last three Operating Expenses figures came in at -$71.5 million (Q4 2025), $4.6 million (Q3 2025), and $3.2 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - 4.33 Mn
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - 32.68 Mn
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - 2.97 Mn
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - 15.76 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -3.82 Mn
7 Psyence Biomedical 241.78 Bn 241.78 Bn - 574,669.00
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 1.85 Bn
9 Abivax 94.26 Bn 94.26 Bn - -67.40 Mn
10 GH Research 9.73 Bn 9.63 Bn - -71.47 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -71.47 Mn
Sep 30, 2025 4.57 Mn
Jun 30, 2025 3.21 Mn
Mar 31, 2025 2.97 Mn
Dec 31, 2024 -66.56 Mn
Sep 30, 2024 4.17 Mn
Jun 30, 2024 6.29 Mn
Mar 31, 2024 5.79 Mn
Dec 31, 2023 28.15 Mn
Sep 30, 2023 4.46 Mn
Jun 30, 2023 4.43 Mn
Mar 31, 2023 4.19 Mn
Dec 31, 2022 24.79 Mn
Sep 30, 2022 2.61 Mn
Jun 30, 2022 1.73 Mn
Mar 31, 2022 -8.01 Mn
Dec 31, 2021 23.58 Mn
Sep 30, 2021 -4.67 Mn
Jun 30, 2021 -2.67 Mn
Mar 31, 2021 -1.14 Mn