GH Research (GHRS) Operating Expenses (2020 - 2026)

GH Research (GHRS) posted quarterly Operating Expenses of -$71.5 million for Q4 2025, down 7.37% year-over-year from -$77.2 million in Q4 2024, and down 1664.26% quarter-over-quarter from $4.6 million in Q3 2025.

GH Research (GHRS) Operating Expenses (2020 - 2026) Analysis & Trends

GH Research's Operating Expenses history runs 6 years deep, the most recent figure standing at -$71.5 million for Q4 2025.

  • In Q4 2025, Operating Expenses fell 7.37% year-over-year to -$71.5 million; the TTM figure through Dec 2025 stood at -$60.7 million (down 20.68% YoY), while the FY2025 annual figure was $60.7 million, up 20.68% from the prior year.
  • Operating Expenses for Q4 2025 stood at -$71.5 million, down from $4.6 million in the prior quarter.
  • The five-year high for Operating Expenses was $28.1 million in Q4 2023, with the low at -$71.5 million in Q4 2025.
  • The 5-year median for Operating Expenses is $3.7 million (2024), against an average of -$1.7 million.
  • Peak annual rise in Operating Expenses reached 4058.55% in 2021, while the deepest fall reached 7676.67% in 2021.
  • GH Research's Operating Expenses stood at $23.6 million in 2021, then increased by 5.13% to $24.8 million in 2022, then climbed by 13.54% to $28.1 million in 2023, then sank by 336.5% to -$66.6 million in 2024, then dropped by 7.37% to -$71.5 million in 2025.
  • Business Quant data shows GHRS's Operating Expenses at -$71.5 million in Q4 2025, $4.6 million in Q3 2025, and $3.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 2.89 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.21 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 4,978.15
7 Royalty Pharma 33.72 Bn 35.84 Bn - 541.02 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.06 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 427.03 Mn
10 GH Research 2.02 Bn 1.68 Bn - 19.46 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 19.46 Mn
Dec 31, 2025 -71.47 Mn
Sep 30, 2025 4.57 Mn
Jun 30, 2025 3.21 Mn
Mar 31, 2025 2.97 Mn
Dec 31, 2024 -66.56 Mn
Sep 30, 2024 4.17 Mn
Jun 30, 2024 6.29 Mn
Mar 31, 2024 5.79 Mn
Dec 31, 2023 28.15 Mn
Sep 30, 2023 4.46 Mn
Jun 30, 2023 4.43 Mn
Mar 31, 2023 4.19 Mn
Dec 31, 2022 24.79 Mn
Sep 30, 2022 2.61 Mn
Jun 30, 2022 1.73 Mn
Mar 31, 2022 -8.01 Mn
Dec 31, 2021 23.58 Mn
Sep 30, 2021 -4.67 Mn
Jun 30, 2021 -2.67 Mn