Denali Therapeutics DNLI
NASDAQ DNLI
$20.00 -0.53 (-2.58%)
At close: Oct 2, 2026 · 4:00 PM EDT

Denali Therapeutics (DNLI) Return on Sales [ROS] (2018 - 2026)

Updated

Denali Therapeutics (DNLI) recorded Return on Sales [ROS] of -3622.11% in Q2 2026.

Analysis

Denali Therapeutics (DNLI) Return on Sales [ROS] (2018 - 2026) Analysis & Trends

On a TTM basis, Denali Therapeutics' Return on Sales [ROS] came in at -15058.19% as of Jun 30, 2026; for FY2023, it came in at -59.51%, up 254.65 percentage points from FY2022.

  • Annual Return on Sales [ROS] has a five-year change of -23.61 percentage points (FY2018 to FY2023).
  • Across earlier years, Return on Sales [ROS] came in at -314.16% in FY2022 (+293.62 pp), -607.78% in FY2021 (-626.46 pp), 18.69% in FY2020 (+817.79 pp) and -799.10% in FY2019 (-763.20 pp).
  • The Q2 2026 figure is the highest quarterly Return on Sales [ROS] since Q1 2024.
  • Peak year-over-year performance for Return on Sales [ROS] in the last five years was a gain of 964.94 percentage points in Q4 2023, against a drop of 37996.01 percentage points in Q2 2024 at the low end.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Eli Lilly 1,082.65 Bn 1,051.23 Bn 19.71 Bn 51.16%
2 Johnson & Johnson 623.68 Bn 542.21 Bn 17.26 Bn 28.21%
3 AbbVie 459.43 Bn 432.59 Bn 12.70 Bn 37.86%
4 Merck 354.80 Bn 309.23 Bn 12.21 Bn -3.52%
5 Novartis Ag 269.16 Bn 225.03 Bn 11.24 Bn 32.97%
6 Astrazeneca 244.40 Bn 217.97 Bn 12.86 Bn 20.57%
7 Amgen 220.17 Bn 175.57 Bn 7.24 Bn 34.95%
8 Gilead Sciences 183.05 Bn 157.16 Bn 6.22 Bn -133.21%
9 Pfizer 160.27 Bn 107.22 Bn 10.94 Bn 28.37%
10 Denali Therapeutics 3.28 Bn 3.28 Bn 3.51 Mn -3,622.11%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -3,622.11%
Jun 30, 2024 -37,938.04%
Mar 31, 2024 -65.54%
Dec 31, 2023 -59.51%
Sep 30, 2023 -8,981.45%
Jun 30, 2023 57.96%
Mar 31, 2023 -343.80%
Dec 31, 2022 -1,024.45%
Sep 30, 2022 -3,020.12%
Jun 30, 2022 -117.03%
Mar 31, 2022 -157.80%
Dec 31, 2021 -616.28%
Sep 30, 2021 -1,619.55%
Jun 30, 2021 -269.48%
Mar 31, 2021 -898.90%
Dec 31, 2020 77.04%
Sep 30, 2020 -640.01%
Jun 30, 2020 -1,048.01%
Mar 31, 2020 -1,663.90%
Dec 31, 2019 -1,236.26%
API Access

Denali Therapeutics Return on Sales [ROS] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=DNLI&period=max&api_key=YOUR_API_KEY