Denali Therapeutics DNLI Institutional Ownership

NASDAQ DNLI

$18.93 +0.89 (+4.93%)

At close: Oct 20, 2026 · 4:00 PM EDT

Institutions by Trading Activity

290 Institutions

Increased 173 59.7%

Unchanged 49 16.9%

Reduced 68 23.4%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

83.39%

▲+4.40 pp QoQ

Shares Held by Institutions

156.20Mn

of 187.31Mn outstanding

▲+5.95% QoQ

Shares Outstanding

187.31Mn

31.12Mn held outside 13F filers

Institutional Investors

290

filed 13F for Jun 2026

▲+22 vs prior quarter

Net Shares Added (QoQ)

+8.77Mn

accumulated since last quarter

Value of Holdings

$2.86Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 11, 2026

Denali Therapeutics Inc. (NASDAQ:DNLI) appeared in the 13F filings of 290 institutional investors for the quarter ended June 30, 2026.

Collectively, these holders controlled 83.39% of Denali Therapeutics' outstanding shares in Q2 2026, up from 78.99% in Q1 2026.
Total holdings of DNLI shares rose 5.95% from Q1 2026, and the holder count rose 28.32% from Q2 2025.
Of the 290 holders, 173 added to their positions, 68 reduced their stakes and 49 left their positions unchanged in Q2 2026.
Institutional investors held 156.2Mn shares of Denali Therapeutics in total at the end of Q2 2026, up 8.77Mn from the prior quarter and up 21.19Mn from a year earlier.
As of June 30, 2026, the biggest holder of Denali Therapeutics was T. Rowe Price Investment Management, Inc. with 16.18Mn shares, or 8.64% of shares outstanding.
Holders that added the most shares of Denali Therapeutics in Q2 2026 were T. Rowe Price Investment Management, Inc. (+7.66Mn shares), Nomura Asset Management International Inc. (+2.09Mn shares), BNP Paribas Asset Management Holding S.A. (+1.06Mn shares), BlackRock, Inc. (+991.98K shares) and State Street Corp (+777.3K shares).
Holders that trimmed the most shares of Denali Therapeutics in Q2 2026 while keeping a position were Lynx1 Capital Management LP (-1.87Mn shares), Alyeska Investment Group, L.P. (-1.72Mn shares), UBS Asset Management Americas (-1.27Mn shares), Defilade Capital Management, L.P. (-968.1K shares) and ADAR1 Capital Management, LLC (-842.38K shares).
Per Business Quant, the top 10 investors in DNLI for the quarter ended June 30, 2026 were T. Rowe Price Investment Management, Inc. (16.18Mn shares), BlackRock, Inc. (14.03Mn shares), Baillie Gifford & Co (11.96Mn shares), State Street Corp (7.05Mn shares), Temasek Holdings (Private) Ltd (7.01Mn shares), Vanguard Portfolio Management LLC (6.48Mn shares), Vanguard Capital Management LLC (6.28Mn shares), FMR LLC (4.54Mn shares), Goldman Sachs Group Inc (4.16Mn shares) and Geode Capital Management, LLC (3.97Mn shares).

Form 13F Holdings

290 Institutional Holders

Report period 30 Jun, 2026

Total shares held 156.20Mn

Of outstanding 83.39%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	T. Rowe Price Investment Management, Inc.	0001897612	16,178,963	8.64%	▲7,659,771	+89.91%	$416.12K
2	BlackRock, Inc.	0002012383	14,026,094	7.49%	▲991,979	+7.61%	$360.75Mn
3	BAILLIE GIFFORD & CO	0001088875	11,960,230	6.39%	▼106,249	-0.88%	$307.62Mn
4	State Street Corp	0000093751	7,049,304	3.76%	▲777,303	+12.39%	$181.31Mn
5	Temasek Holdings (Private) Ltd	0001021944	7,012,974	3.74%	0	0.00%	$180.37Mn
6	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	6,477,057	3.46%	▲356,897	+5.83%	$166.59Mn
7	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	6,275,729	3.35%	▲127,772	+2.08%	$161.41Mn
8	FMR LLC	0000315066	4,535,836	2.42%	▼39,538	-0.86%	$116.66Mn
9	Goldman Sachs Group Inc	0000886982	4,155,895	2.22%	▼251,360	-5.70%	$106.89Mn
10	GEODE CAPITAL MANAGEMENT, LLC	0001214717	3,973,342	2.12%	▲246,228	+6.61%	$102.21Mn
11	Holocene Advisors, LP	0001700574	3,905,225	2.08%	▲709,796	+22.21%	$100.44Mn
12	BAKER BROS. ADVISORS LP	0001263508	3,734,336	1.99%	▲2,641	+0.07%	$96.05Mn
13	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	0000861177	3,161,972	1.69%	▼1,270,342	-28.66%	$81.33Mn
14	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	3,136,149	1.67%	▲672,003	+27.27%	$80.66K
15	UBS Group AG	0001610520	3,120,592	1.67%	▲549,248	+21.36%	$80.26Mn
16	ALLIANCEBERNSTEIN L.P.	0001109448	2,984,807	1.59%	▲91,189	+3.15%	$57.31Mn
17	DIMENSIONAL FUND ADVISORS LP	0000354204	2,860,604	1.53%	▲168,429	+6.26%	$73.58Mn
18	NORGES BANK	0001374170	2,824,746	1.51%	▲2,824,746	0.00%	$72.65Mn
19	Pictet Asset Management Holding SA	0001993888	2,791,206	1.49%	▲232,341	+9.08%	$71.89Mn
20	Capital Research Global Investors	0001422848	2,565,817	1.37%	▲51,229	+2.04%	$65.99Mn

Showing 1 to 20 of 290 holders