Denali Therapeutics DNLI Revenue Breakdown

NASDAQ DNLI
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At close: Nov 10, 2026 · 4:00 PM EST
Annual revenue breakdowns for Denali Therapeutics, fiscal 2018 to 2023, as reported in its filings.
Annual history

Denali Therapeutics Revenue by Product & Service

Years FY 2019–2020
Lines 4
FY 2020 Total $335.56M

Lrrk2 Program License was Denali Therapeutics’s largest product and service line in fiscal 2020, bringing in $306.55M of $335.56M (91%).

Denali Therapeutics revenue by product and service, fiscal 2019 to 2020
Product and Service FY 2019 FY 2020
Lrrk2 Program License — $306.55M
Collaboration Agreement Services — $27.16M
Retained Activities $10.39M $969.00K
Option Research Services — $892.00K
Total $26.32M $335.56M
Totals include 2 discontinued lines from earlier reporting.

Denali Therapeutics revenue by product and service: what the figures show

Denali Therapeutics brought in $335.56M from its four product and service lines in fiscal 2020, the year ended December 31, 2020. Denali Therapeutics regrouped these lines after fiscal 2019, so the total does not compare directly with that year's $26.32M. Lrrk2 Program License was the largest at $306.55M (91.4%), ahead of Collaboration Agreement Services at $27.16M (8.1%) and Retained Activities at $969.00K (0.3%). The remaining line, Option Research Services, brought in $892.00K.

Denali Therapeutics began breaking out Lrrk2 Program License in fiscal 2020, Collaboration Agreement Services in fiscal 2020 and Option Research Services in fiscal 2020. Denali Therapeutics stopped reporting Peripheral Program License ($10.00M in fiscal 2019) and Takeda Collaboration Agreement Services ($5.93M in fiscal 2019) as separate lines.

Annual history

Denali Therapeutics Revenue by Collaborative Arrangement & Arrangement Other than Collaborative

Years FY 2018–2023
Lines 3
FY 2023 Total $330.53M

Biogen was Denali Therapeutics’s largest revenue line in fiscal 2023, bringing in $295.53M of $330.53M (89%).

Denali Therapeutics revenue by collaborative arrangement and arrangement other than collaborative, fiscal 2018 to 2023
Collaborative Arrangement and Arrangement Other than Collaborative FY 2018 FY 2019 FY 2020 FY 2021 FY 2022 FY 2023
Biogen $307.44M $3.74M $3.15M $295.53M
Sanofi Collaboration Agreement $1.07M $15.00M $53.40M $25.00M
Takeda Collaboration Agreement $27.16M $29.92M $51.92M $10.00M
Total $335.66M $48.66M $108.46M $330.53M

Denali Therapeutics revenue by collaborative arrangement and arrangement other than collaborative: what the figures show

Denali Therapeutics brought in $330.53M from its three revenue lines in fiscal 2023, the year ended December 31, 2023. That was up 204.7% from $108.46M in fiscal 2022. Biogen was the largest at $295.53M (89.4%), ahead of Sanofi Collaboration Agreement at $25.00M (7.6%) and Takeda Collaboration Agreement at $10.00M (3.0%).

Compared with fiscal 2022, Biogen grew fastest, up 9,284.9% to $295.53M, while Takeda Collaboration Agreement fell the most, down 80.7% to $10.00M. From fiscal 2020 to 2023, combined revenue from these revenue lines fell from $335.66M to $330.53M, a compound annual decline of 0.5%. Biogen's share of the total fell from 91.6% to 89.4%.

Questions

Denali Therapeutics Revenue Breakdown FAQ

How does Denali Therapeutics make money?

Denali Therapeutics (DNLI) reports its revenue by product and service and by collaborative arrangement and arrangement other than collaborative. In fiscal 2020, Lrrk2 Program License was its largest product and service line, bringing in $306.55M (91.4% of the total), followed by Collaboration Agreement Services at $27.16M (8.1%).

What is Denali Therapeutics' largest product and service line?

Lrrk2 Program License was Denali Therapeutics' largest product and service line in fiscal 2020, bringing in $306.55M, or 91.4% of the $335.56M total across its four product and service lines.

What is Denali Therapeutics' largest revenue line?

Biogen was Denali Therapeutics' largest revenue line in fiscal 2023, bringing in $295.53M, or 89.4% of the $330.53M total across its three revenue lines.

Which Denali Therapeutics revenue line is growing the fastest?

Among Denali Therapeutics' revenue lines that make up at least 2% of revenue, Biogen grew fastest in fiscal 2023, up 9,284.9% from $3.15M to $295.53M.

Where does this revenue breakdown data come from?

Every figure comes from Denali Therapeutics' annual financial filings, as reported. Each line keeps the name Denali Therapeutics gives it, and years follow its fiscal calendar.

How far back does Denali Therapeutics' revenue breakdown go?

Denali Therapeutics' revenue by product and service goes back to fiscal 2019, with figures through fiscal 2020. The latest four fiscal years are free to view, and the full history is available with a Business Quant subscription.