Denali Therapeutics (DNLI) Return on Assets [ROA] (2018 - 2026)
Denali Therapeutics' Return on Assets [ROA] was -42.11% in Q3 2026, up 2.77 percentage points from -44.89% a year earlier and up 0.08 percentage points from the prior quarter.
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Analysis
Denali Therapeutics (DNLI) Return on Assets [ROA] (2018 - 2026) Analysis & Trends
For FY2025, Return on Assets [ROA] at Denali Therapeutics came in at -40.69%, down 7.25 percentage points from FY2024.
- Return on Assets [ROA] shows a five-year change of -47.29 percentage points (FY2020 to FY2025).
- In earlier years, Return on Assets [ROA] was -33.45% in FY2024 (-22.34 pp), -11.11% in FY2023 (+11.65 pp), -22.76% in FY2022 (-3.44 pp) and -19.32% in FY2021 (-25.91 pp).
- The Q3 2026 figure marks the highest quarterly Return on Assets [ROA] since Q2 2025.
- Compared with a year earlier, Return on Assets [ROA] was higher in 1 of the last eight quarters, with an average year-over-year change of -11.84 percentage points.
- The best year-over-year quarter for Return on Assets [ROA] over five years was Q1 2024 (a gain of 15.79 percentage points); the worst was Q3 2022 (a drop of 26.11 percentage points).
- Per Business Quant data, DNLI's Return on Assets [ROA] in the three quarters before Q3 2026 was -42.19% (Q2 2026), -42.14% (Q1 2026) and -46.58% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 19.00% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 8.08% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 7.32% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 1.87% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 9.36% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 9.80% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -7.67% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 2.00% |
| 10 | Denali Therapeutics | 3.18 Bn | 98.89 Mn | 17.59 Mn | -42.38% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -42.38% |
| Jun 30, 2026 | -42.44% |
| Mar 31, 2026 | -42.37% |
| Dec 31, 2025 | -46.71% |
| Sep 30, 2025 | -45.29% |
| Jun 30, 2025 | -39.01% |
| Mar 31, 2025 | -34.07% |
| Dec 31, 2024 | -29.80% |
| Sep 30, 2024 | -8.03% |
| Jun 30, 2024 | -7.67% |
| Mar 31, 2024 | 12.11% |
| Dec 31, 2023 | 13.71% |
| Sep 30, 2023 | -8.99% |
| Jun 30, 2023 | -8.74% |
| Mar 31, 2023 | -25.36% |
| Dec 31, 2022 | -24.58% |
| Sep 30, 2022 | -24.91% |
| Jun 30, 2022 | -22.64% |
| Mar 31, 2022 | -21.63% |
| Dec 31, 2021 | -20.52% |
API Access
Denali Therapeutics Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=DNLI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "DNLI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=DNLI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();