Definium Therapeutics (DFTX) EBITDA (2021 - 2026)
Definium Therapeutics (DFTX) posted quarterly EBITDA of -$59.2 million for Q1 2026, down 84.15% year-over-year from -$373.6 million in Q1 2025, and down 24.47% quarter-over-quarter from -$47.6 million in Q4 2025.
Analysis
Definium Therapeutics (DFTX) EBITDA (2021 - 2026) Analysis & Trends
Definium Therapeutics (DFTX) has reported EBITDA for 6 consecutive years, with -$59.2 million the latest figure, recorded in Q1 2026.
- In Q1 2026, EBITDA fell 84.15% year-over-year to -$59.2 million; the TTM figure through Mar 2026 stood at -$193.4 million (down 69.81% YoY), while the FY2025 annual figure was -$166.3 million, down 60.04% from the prior year.
- EBITDA declined to -$59.2 million in Q1 2026 per DFTX's latest filing, from -$47.6 million in the prior quarter.
- Across five years, EBITDA topped out at -$13.9 million in Q4 2022 and bottomed at -$59.2 million in Q1 2026.
- Historically, EBITDA has averaged -$28.8 million across 5 years, with a median of -$24.5 million in 2024.
- Annual changes were most pronounced in 2022 — EBITDA surged 62.53% — and 2025, when it plunged 84.21%.
- Definium Therapeutics' EBITDA stood at -$13.9 million in 2022, then plunged by 59.75% to -$22.2 million in 2023, then sank by 46.19% to -$32.5 million in 2024, then plunged by 46.57% to -$47.6 million in 2025, then retreated by 24.47% to -$59.2 million in 2026.
- Business Quant data shows DFTX's EBITDA at -$59.2 million in Q1 2026, -$47.6 million in Q4 2025, and -$45.7 million in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 493.00 Mn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -815.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -505.13 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 325.05 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 133.12 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Definium Therapeutics | 4.23 Bn | 4.23 Bn | - | -75.08 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -75.08 Mn |
| Mar 31, 2026 | -59.22 Mn |
| Dec 31, 2025 | -47.58 Mn |
| Sep 30, 2025 | -45.67 Mn |
| Jun 30, 2025 | -40.90 Mn |
| Mar 31, 2025 | -32.16 Mn |
| Dec 31, 2024 | -32.46 Mn |
| Sep 30, 2024 | -24.79 Mn |
| Jun 30, 2024 | -24.46 Mn |
| Mar 31, 2024 | -22.20 Mn |
| Dec 31, 2023 | -22.21 Mn |
| Sep 30, 2023 | -21.62 Mn |
| Jun 30, 2023 | -29.18 Mn |
| Mar 31, 2023 | -20.86 Mn |
| Dec 31, 2022 | -13.90 Mn |
| Sep 30, 2022 | -16.98 Mn |
| Jun 30, 2022 | -16.94 Mn |
| Mar 31, 2022 | -18.51 Mn |
| Dec 31, 2021 | -17.56 Mn |
| Sep 30, 2021 | -17.23 Mn |