Definium Therapeutics (DFTX) EBITDA (2019 - 2026)
Definium Therapeutics (DFTX) reported EBITDA of -$77.4 million for Q1 2026, down 231.09% year-over-year from $59.0 million in Q1 2025, and down 53.64% quarter-over-quarter from -$50.4 million in Q4 2025.
Definium Therapeutics (DFTX) EBITDA (2019 - 2026) Analysis & Trends
Definium Therapeutics (DFTX) has 7 years of EBITDA data on file, last reported at -$77.4 million in Q1 2026.
- EBITDA for Q1 2026 came in at -$77.4 million, down 231.09% year-over-year; the trailing twelve-month figure through Mar 2026 was -$237.5 million (down 205.84% YoY), and the FY2025 annual result was -$183.5 million, down 69.61% from the prior year.
- EBITDA eased to -$77.4 million in Q1 2026 per DFTX's latest filing, from -$50.4 million in the prior quarter.
- Over five years, EBITDA peaked at -$5.0 million in Q4 2022 and troughed at -$77.4 million in Q1 2026.
- A 5-year average of -$30.7 million and a median of -$24.3 million in 2023 frame the typical range for EBITDA.
- The sharpest annual moves came in 2024 and 2025: EBITDA jumped 80.08% in 2024, then slumped 629.71% in 2025.
- A 5-year view of EBITDA shows it stood at -$5.0 million in 2022, then plunged by 384.12% to -$24.3 million in 2023, then plunged by 42.99% to -$34.7 million in 2024, then plunged by 44.93% to -$50.4 million in 2025, then slumped by 53.64% to -$77.4 million in 2026.
- Business Quant data shows DFTX's EBITDA at -$77.4 million in Q1 2026, -$50.4 million in Q4 2025, and -$67.1 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Definium Therapeutics | 2.46 Bn | 2.09 Bn | - | -77.36 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -77.36 Mn |
| Dec 31, 2025 | -50.35 Mn |
| Sep 30, 2025 | -67.07 Mn |
| Jun 30, 2025 | -42.74 Mn |
| Mar 31, 2025 | -23.37 Mn |
| Dec 31, 2024 | -34.74 Mn |
| Sep 30, 2024 | -13.70 Mn |
| Jun 30, 2024 | -5.86 Mn |
| Mar 31, 2024 | -53.91 Mn |
| Dec 31, 2023 | -24.30 Mn |
| Sep 30, 2023 | -17.51 Mn |
| Jun 30, 2023 | -29.41 Mn |
| Mar 31, 2023 | -24.80 Mn |
| Dec 31, 2022 | -5.02 Mn |
| Sep 30, 2022 | -16.59 Mn |
| Jun 30, 2022 | -17.10 Mn |
| Mar 31, 2022 | -18.50 Mn |
| Dec 31, 2021 | -16.45 Mn |
| Sep 30, 2021 | -17.58 Mn |
| Jun 30, 2021 | -44.55 Mn |