Definium Therapeutics (DFTX) EBITDA (2021 - 2026)
Definium Therapeutics' (DFTX) quarterly EBITDA came in at -$59.2 million in Q1 2026, down 84.15% year-on-year from -$373.6 million in Q1 2025, and down 24.47% on a QoQ basis from -$47.6 million in Q4 2025.
Definium Therapeutics (DFTX) EBITDA (2021 - 2026) Analysis & Trends
Definium Therapeutics (DFTX) has 6 years of EBITDA data on file, last reported at -$59.2 million in Q1 2026.
- On a quarterly basis, EBITDA fell 84.15% year-over-year to -$59.2 million in Q1 2026; TTM through Mar 2026 was -$193.4 million, a 69.81% decrease from a year earlier, with the FY2025 full-year figure at -$166.3 million, down 60.04% from the prior year.
- EBITDA for Q1 2026 stood at -$59.2 million, down from -$47.6 million in the prior quarter.
- Over the last five years, EBITDA for DFTX reached as high as -$13.9 million in Q4 2022 and fell as low as -$59.2 million in Q1 2026.
- Historically, EBITDA has averaged -$28.8 million across 5 years, with a median of -$24.5 million in 2024.
- Across the five-year window, EBITDA soared 62.53% in 2022 and slumped 84.21% in 2025, its largest moves.
- Year by year, EBITDA stood at -$13.9 million in 2022, then plunged by 59.75% to -$22.2 million in 2023, then sank by 46.19% to -$32.5 million in 2024, then plunged by 46.57% to -$47.6 million in 2025, then slipped by 24.47% to -$59.2 million in 2026.
- Per Business Quant data, the three most recent EBITDA figures were -$59.2 million in Q1 2026, -$47.6 million in Q4 2025, and -$45.7 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Definium Therapeutics | 4.71 Bn | 4.71 Bn | - | -59.22 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -59.22 Mn |
| Dec 31, 2025 | -47.58 Mn |
| Sep 30, 2025 | -45.67 Mn |
| Jun 30, 2025 | -40.90 Mn |
| Mar 31, 2025 | -32.16 Mn |
| Dec 31, 2024 | -32.46 Mn |
| Sep 30, 2024 | -24.79 Mn |
| Jun 30, 2024 | -24.46 Mn |
| Mar 31, 2024 | -22.20 Mn |
| Dec 31, 2023 | -22.21 Mn |
| Sep 30, 2023 | -21.62 Mn |
| Jun 30, 2023 | -29.18 Mn |
| Mar 31, 2023 | -20.86 Mn |
| Dec 31, 2022 | -13.90 Mn |
| Sep 30, 2022 | -16.98 Mn |
| Jun 30, 2022 | -16.94 Mn |
| Mar 31, 2022 | -18.51 Mn |
| Dec 31, 2021 | -17.56 Mn |
| Sep 30, 2021 | -17.23 Mn |
| Jun 30, 2021 | -45.22 Mn |