Definium Therapeutics (DFTX) EBITDA (2021 - 2026)

Definium Therapeutics' (DFTX) quarterly EBITDA came in at -$59.2 million in Q1 2026, down 84.15% year-on-year from -$373.6 million in Q1 2025, and down 24.47% on a QoQ basis from -$47.6 million in Q4 2025.

Definium Therapeutics (DFTX) EBITDA (2021 - 2026) Analysis & Trends

Definium Therapeutics (DFTX) has 6 years of EBITDA data on file, last reported at -$59.2 million in Q1 2026.

  • On a quarterly basis, EBITDA fell 84.15% year-over-year to -$59.2 million in Q1 2026; TTM through Mar 2026 was -$193.4 million, a 69.81% decrease from a year earlier, with the FY2025 full-year figure at -$166.3 million, down 60.04% from the prior year.
  • EBITDA for Q1 2026 stood at -$59.2 million, down from -$47.6 million in the prior quarter.
  • Over the last five years, EBITDA for DFTX reached as high as -$13.9 million in Q4 2022 and fell as low as -$59.2 million in Q1 2026.
  • Historically, EBITDA has averaged -$28.8 million across 5 years, with a median of -$24.5 million in 2024.
  • Across the five-year window, EBITDA soared 62.53% in 2022 and slumped 84.21% in 2025, its largest moves.
  • Year by year, EBITDA stood at -$13.9 million in 2022, then plunged by 59.75% to -$22.2 million in 2023, then sank by 46.19% to -$32.5 million in 2024, then plunged by 46.57% to -$47.6 million in 2025, then slipped by 24.47% to -$59.2 million in 2026.
  • Per Business Quant data, the three most recent EBITDA figures were -$59.2 million in Q1 2026, -$47.6 million in Q4 2025, and -$45.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Definium Therapeutics 4.71 Bn 4.71 Bn - -59.22 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -59.22 Mn
Dec 31, 2025 -47.58 Mn
Sep 30, 2025 -45.67 Mn
Jun 30, 2025 -40.90 Mn
Mar 31, 2025 -32.16 Mn
Dec 31, 2024 -32.46 Mn
Sep 30, 2024 -24.79 Mn
Jun 30, 2024 -24.46 Mn
Mar 31, 2024 -22.20 Mn
Dec 31, 2023 -22.21 Mn
Sep 30, 2023 -21.62 Mn
Jun 30, 2023 -29.18 Mn
Mar 31, 2023 -20.86 Mn
Dec 31, 2022 -13.90 Mn
Sep 30, 2022 -16.98 Mn
Jun 30, 2022 -16.94 Mn
Mar 31, 2022 -18.51 Mn
Dec 31, 2021 -17.56 Mn
Sep 30, 2021 -17.23 Mn
Jun 30, 2021 -45.22 Mn