Cyclerion Therapeutics (CYCN) Net Margin (2019 - 2025)

Cyclerion Therapeutics (CYCN) recorded quarterly Net Margin of 114.97% in Q3 2025, up 93.61% quarter-over-quarter from 1797.85% in Q2 2025.

Cyclerion Therapeutics (CYCN) Net Margin (2019 - 2025) Analysis & Trends

Cyclerion Therapeutics' Net Margin history runs 5 years deep, the most recent figure standing at 114.97% for Q3 2025.

  • In Q3 2025, Net Margin changed N/A year-over-year to 114.97%; the TTM figure through Sep 2025 stood at 144.83% (changed N/A YoY), while the FY2022 annual figure was 8697.64%, down 729747.0% from the prior year.
  • Net Margin was 114.97% for Q3 2025 at Cyclerion Therapeutics, up from 1797.85% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 114.97% in Q3 2025 to a low of 21604.84% in Q1 2021.
  • Historically, Net Margin has averaged 4222.73% across 3 years, with a median of 1826.16% in 2022.
  • The sharpest annual moves came in 2021 and 2022: Net Margin slumped 1960997 bps in 2021, then jumped 1977868 bps in 2022.
  • A 3-year view of Net Margin shows it stood at 2690.06% in 2021, then tumbled by 63 bps to 4389.87% in 2022, then soared by 97 bps to 114.97% in 2025.
  • The last three Net Margin figures came in at 114.97% (Q3 2025), 1797.85% (Q2 2025), and 1798.77% (Q1 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - -
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn 0.82%
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 34.53%
9 Abivax 94.37 Bn 94.37 Bn - -
10 Cyclerion Therapeutics 11.50 Mn 8.26 Mn - -

Historic Data

Download Data
DateValue
Sep 30, 2025 -114.97%
Jun 30, 2025 -1,797.85%
Mar 31, 2025 -1,798.77%
Jun 30, 2022 -4,389.87%
Mar 31, 2022 -1,826.16%
Dec 31, 2021 -2,690.06%
Sep 30, 2021 -3,242.82%
Jun 30, 2021 -539.20%
Mar 31, 2021 -21,604.84%
Dec 31, 2020 -14,457.14%
Sep 30, 2020 -5,421.75%
Jun 30, 2020 -2,608.01%
Mar 31, 2020 -1,994.87%
Dec 31, 2019 -1,759.28%
Sep 30, 2019 -1,954.01%
Jun 30, 2019 -1,981.20%