Alnylam Pharmaceuticals (ALNY) Net Margin (2009 - 2026)
Alnylam Pharmaceuticals posted quarterly Net Margin of 17.65% for Q1 2026, up 7849.0% year-on-year from 0.22% in Q1 2025, and up 73.58% on a QoQ basis from 10.17% in Q4 2025.
Alnylam Pharmaceuticals (ALNY) has 18 years of Net Margin data on file, last reported at 17.65% in Q1 2026.
- For the quarter ending Q1 2026, Net Margin rose 7849.0% year-over-year to 17.65%; the trailing twelve-month figure through Mar 2026 stood at 12.69% (up 2561.0% YoY), and the FY2025 full-year result was 8.45%, up 2082.0% from the prior year.
- Net Margin for Q1 2026 stood at 17.65%, up from 10.17% in the prior quarter.
- Across five years, Net Margin topped out at 23.43% in Q3 2025 and bottomed at 153.58% in Q3 2022.
- The 5-year median for Net Margin is 22.27% (2024), against an average of 39.7%.
- The widest annual swing landed in 2023, when Net Margin surged 17327 bps; it then tumbled 4750 bps in 2025.
- A 5-year view of Net Margin shows it stood at 61.93% in 2022, then jumped by 49 bps to 31.35% in 2023, then jumped by 55 bps to 14.12% in 2024, then jumped by 172 bps to 10.17% in 2025, then soared by 74 bps to 17.65% in 2026.
- The last three Net Margin figures came in at 17.65% (Q1 2026), 10.17% (Q4 2025), and 23.43% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.82% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 34.53% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 20.17% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 17.65% |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 17.65% |
| Dec 31, 2025 | 10.17% |
| Sep 30, 2025 | 23.43% |
| Jun 30, 2025 | -8.57% |
| Mar 31, 2025 | -60.84% |
| Dec 31, 2024 | -14.12% |
| Sep 30, 2024 | -22.27% |
| Jun 30, 2024 | -2.56% |
| Mar 31, 2024 | -13.34% |
| Dec 31, 2023 | -31.35% |
| Sep 30, 2023 | 19.69% |
| Jun 30, 2023 | -86.59% |
| Mar 31, 2023 | -54.53% |
| Dec 31, 2022 | -61.93% |
| Sep 30, 2022 | -153.58% |
| Jun 30, 2022 | -123.39% |
| Mar 31, 2022 | -112.70% |
| Dec 31, 2021 | -99.97% |
| Sep 30, 2021 | -109.00% |
| Jun 30, 2021 | -85.95% |
| Mar 31, 2021 | -112.80% |
| Dec 31, 2020 | -148.90% |
| Sep 30, 2020 | -201.26% |
| Jun 30, 2020 | -172.40% |
| Mar 31, 2020 | -183.18% |
| Dec 31, 2019 | -385.30% |
| Sep 30, 2019 | -297.65% |
| Jun 30, 2019 | -490.86% |
| Mar 31, 2019 | -546.39% |
| Dec 31, 2018 | -1,005.28% |
| Sep 30, 2018 | -11,855.10% |
| Jun 30, 2018 | -546.90% |
| Mar 31, 2018 | -644.84% |
| Dec 31, 2017 | -375.03% |
| Sep 30, 2017 | -719.10% |
| Jun 30, 2017 | -743.28% |
| Mar 31, 2017 | -565.88% |
| Dec 31, 2016 | -648.76% |
| Sep 30, 2016 | -765.31% |
| Jun 30, 2016 | -1,034.89% |
| Mar 31, 2016 | -1,401.96% |
| Dec 31, 2015 | -1,201.44% |
| Sep 30, 2015 | -1,214.29% |
| Jun 30, 2015 | -821.55% |
| Mar 31, 2015 | -276.25% |
| Dec 31, 2014 | -181.02% |
| Sep 30, 2014 | -400.31% |
| Jun 30, 2014 | -608.49% |
| Mar 31, 2014 | -3,248.50% |
| Dec 31, 2013 | -298.30% |
| Sep 30, 2013 | -330.17% |
| Jun 30, 2013 | -209.15% |
| Mar 31, 2013 | -48.35% |
| Dec 31, 2012 | 513.71% |
| Sep 30, 2012 | -116.37% |
| Jun 30, 2012 | -62.04% |
| Mar 31, 2012 | -55.22% |
| Dec 31, 2011 | 211.09% |
| Sep 30, 2011 | -63.67% |
| Jun 30, 2011 | -67.06% |
| Mar 31, 2011 | -77.93% |
| Dec 31, 2010 | -32.70% |
| Sep 30, 2010 | -34.81% |
| Jun 30, 2010 | -54.97% |
| Mar 31, 2010 | -50.17% |
| Dec 31, 2009 | -29.26% |
| Sep 30, 2009 | -37.97% |
| Jun 30, 2009 | -92.28% |