BioNTech SE (BNTX) Net Margin (2018 - 2025)

BioNTech SE (BNTX) posted Net Margin of 16.51% for Q4 2025, down 421.06% sequentially from 5.14% in Q3 2025, and down 1652.0% YoY from 1.06% in Q4 2024.

BioNTech SE (BNTX) Net Margin (2018 - 2025) Analysis & Trends

BioNTech SE has reported Net Margin for 8 years, with the latest figure at 16.51% in Q4 2025.

  • Quarterly Net Margin fell 1652.0% year-over-year to 16.51% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 31.84% (down 3182.0% YoY) and the FY2025 annual result came in at 39.59%, down 1540.0% from the prior year.
  • Net Margin fell to 16.51% in Q4 2025 per BNTX's latest filing, from 5.14% in the prior quarter.
  • Over five years, Net Margin peaked at 105.28% in Q1 2021 and troughed at 624.55% in Q2 2024.
  • A 5-year average of 38.28% and a median of 21.22% in 2023 frame the typical range for Net Margin.
  • The sharpest annual moves came in 2023 and 2025: Net Margin slumped 47086 bps in 2023, then surged 46397 bps in 2025.
  • Over 5 years, Net Margin stood at 0.0% in 2021, then soared by 166085745 bps to 95.05% in 2022, then slumped by 38 bps to 58.72% in 2023, then slumped by 100 bps to 0.01% in 2024, then plunged by 158976 bps to 16.51% in 2025.
  • According to Business Quant data, Net Margin over the past three periods registered 16.51%, 5.14%, and 160.58% for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 BioNTech SE 23.54 Bn 5.15 Bn 668.28 Mn -16.51%

Historic Data

Download Data
DateValue
Dec 31, 2025 -16.51%
Sep 30, 2025 5.14%
Jun 30, 2025 -160.58%
Mar 31, 2025 -259.85%
Dec 31, 2024 28.82%
Sep 30, 2024 9.58%
Jun 30, 2024 -624.55%
Mar 31, 2024 -185.77%
Dec 31, 2023 58.72%
Sep 30, 2023 32.86%
Jun 30, 2023 -378.06%
Mar 31, 2023 71.51%
Dec 31, 2022 95.05%
Sep 30, 2022 89.66%
Jun 30, 2022 92.81%
Mar 31, 2022 99.42%
Dec 31, 2021 0.00%
Sep 30, 2021 100.60%
Jun 30, 2021 99.06%
Mar 31, 2021 105.28%