Growth Metrics

BioNTech SE (BNTX) Net Margin (2018 - 2025)

BioNTech SE (BNTX) posted Net Margin of 16.51% for Q4 2025, down 773.7% on a QoQ basis from 1.89% in Q3 2025, and down 4532.0% year-over-year from 0.37% in Q4 2024.

BioNTech SE (BNTX) has 8 years of Net Margin data on file, last reported at 16.51% in Q4 2025.

  • In Q4 2025, Net Margin fell 4532.0% year-over-year to 16.51%; the TTM figure through Dec 2025 stood at 32.62% (down 794.0% YoY), while the FY2025 annual figure was 39.59%, up 58805.0% from the prior year.
  • Net Margin fell to 16.51% in Q4 2025, from 1.89% in the prior quarter.
  • Across five years, Net Margin topped out at 105.28% in Q1 2021 and bottomed at 2450.61% in Q2 2024.
  • A 5-year average of 138.14% and a median of 23.38% in 2023 frame the typical range for Net Margin.
  • Annual changes were most pronounced in 2024 — Net Margin sank 207255 bps — and 2025, when it soared 230237 bps.
  • Year by year, Net Margin stood at 0.0% in 2021, then soared by 93067603 bps to 53.26% in 2022, then advanced by 10 bps to 58.72% in 2023, then plunged by 51 bps to 28.82% in 2024, then slumped by 157 bps to 16.51% in 2025.
  • The last three Net Margin figures came in at 16.51% (Q4 2025), 1.89% (Q3 2025), and 148.24% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 0.82%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 34.53%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 20.17%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.65%
10 BioNTech SE 27.66 Bn 7.53 Bn 668.28 Mn -16.51%

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -33.61%
Sep 30, 2025 5.14%
Jun 30, 2025 -148.24%
Mar 31, 2025 -2,047.41%
Dec 31, 2024 7,863.64%
Sep 30, 2024 15.91%
Jun 30, 2024 -2,462.80%
Mar 31, 2024 -3,788.04%
Dec 31, 2023 58.72%
Sep 30, 2023 32.86%
Jun 30, 2023 -113.54%
Mar 31, 2023 71.51%
Dec 31, 2022 53.26%
Sep 30, 2022 51.57%
Jun 30, 2022 92.81%
Mar 31, 2022 99.42%
Dec 31, 2021 0.00%
Sep 30, 2021 24.00%
Jun 30, 2021 99.06%
Mar 31, 2021 80.17%
Dec 31, 2020 0.00%
Sep 30, 2020 307.41%
Jun 30, 2020 211.44%
Mar 31, 2020 192.78%
Sep 30, 2019 -105.03%
Jun 30, 2019 194.19%
Mar 31, 2019 155.83%
Dec 31, 2018 73.09%
Sep 30, 2018 -114.88%