Cyclerion Therapeutics (CYCN) Enterprise Value (2019 - 2025)

Cyclerion Therapeutics (CYCN) recorded quarterly Enterprise Value of -$3.2 million in Q4 2025, up 29.07% quarter-over-quarter from -$4.6 million in Q3 2025, and little changed on a YoY basis from -$3.2 million in Q4 2024.

Cyclerion Therapeutics (CYCN) Enterprise Value (2019 - 2025) Analysis & Trends

Cyclerion Therapeutics' Enterprise Value history runs 7 years deep, the most recent figure standing at -$3.2 million for Q4 2025.

  • In Q4 2025, Enterprise Value changed 0.25% year-over-year to -$3.2 million; the TTM figure through Dec 2025 stood at -$3.2 million (changed 0.25% YoY), while the FY2025 annual figure was -$3.2 million, changed 0.25% from the prior year.
  • Enterprise Value was -$3.2 million for Q4 2025 at Cyclerion Therapeutics, up from -$4.6 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$2.9 million in Q3 2024 to a low of -$70.4 million in Q2 2021.
  • Historically, Enterprise Value has averaged -$19.7 million across 5 years, with a median of -$7.4 million in 2023.
  • The sharpest annual moves came in 2023 and 2025: Enterprise Value jumped 82.57% in 2023, then plunged 59.05% in 2025.
  • A 5-year view of Enterprise Value shows it stood at -$54.0 million in 2021, then surged by 75.2% to -$13.4 million in 2022, then surged by 43.42% to -$7.6 million in 2023, then surged by 57.31% to -$3.2 million in 2024, then decreased by 0.25% to -$3.2 million in 2025.
  • The last three Enterprise Value figures came in at -$3.2 million (Q4 2025), -$4.6 million (Q3 2025), and -$3.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -32.30 Mn
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - -4.14 Mn
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn -286.70 Mn
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -2.77 Mn
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -18.44 Mn
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn -7.25 Bn
9 Abivax 94.37 Bn 94.37 Bn - -584.73 Mn
10 Cyclerion Therapeutics 11.50 Mn 8.26 Mn - -3.24 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.24 Mn
Sep 30, 2025 -4.57 Mn
Jun 30, 2025 -3.01 Mn
Mar 31, 2025 -3.64 Mn
Dec 31, 2024 -3.23 Mn
Sep 30, 2024 -2.87 Mn
Jun 30, 2024 -4.59 Mn
Mar 31, 2024 -5.70 Mn
Dec 31, 2023 -7.57 Mn
Sep 30, 2023 -9.11 Mn
Jun 30, 2023 -5.64 Mn
Mar 31, 2023 -7.17 Mn
Dec 31, 2022 -13.38 Mn
Sep 30, 2022 -20.41 Mn
Jun 30, 2022 -30.32 Mn
Mar 31, 2022 -41.13 Mn
Dec 31, 2021 -53.96 Mn
Sep 30, 2021 -62.50 Mn
Jun 30, 2021 -70.39 Mn
Mar 31, 2021 -41.43 Mn