Cyclerion Therapeutics CYCN
NASDAQ CYCN
$3.81 -0.26 (-6.39%)
As of: Aug 21, 2026 · 2:31 PM EDT

Cyclerion Therapeutics (CYCN) Enterprise Value (2019 - 2025)

Cyclerion Therapeutics (CYCN) posted quarterly Enterprise Value of -$3.2 million for Q4 2025, little changed year-over-year from -$3.2 million in Q4 2024, and up 29.07% quarter-over-quarter from -$4.6 million in Q3 2025.

Cyclerion Therapeutics (CYCN) Enterprise Value (2019 - 2025) Analysis & Trends

Cyclerion Therapeutics' Enterprise Value history runs 7 years deep, the most recent figure standing at -$3.2 million for Q4 2025.

  • In Q4 2025, Enterprise Value changed 0.25% year-over-year to -$3.2 million; the TTM figure through Dec 2025 stood at -$3.2 million (changed 0.25% YoY), while the FY2025 annual figure was -$3.2 million, changed 0.25% from the prior year.
  • Enterprise Value for Q4 2025 stood at -$3.2 million, up from -$4.6 million in the prior quarter.
  • The five-year high for Enterprise Value was -$2.9 million in Q3 2024, with the low at -$70.4 million in Q2 2021.
  • The 5-year median for Enterprise Value is -$7.4 million (2023), against an average of -$19.7 million.
  • The sharpest annual moves came in 2023 and 2025: Enterprise Value surged 82.56% in 2023, then tumbled 59.05% in 2025.
  • Cyclerion Therapeutics' Enterprise Value stood at -$54.0 million in 2021, then jumped by 75.2% to -$13.4 million in 2022, then jumped by 43.42% to -$7.6 million in 2023, then jumped by 57.31% to -$3.2 million in 2024, then retreated by 0.25% to -$3.2 million in 2025.
  • Business Quant data shows CYCN's Enterprise Value at -$3.2 million in Q4 2025, -$4.6 million in Q3 2025, and -$3.0 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 138.79 Bn 130.93 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 85.99 Bn 78.00 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 65.26 Bn 60.07 Bn 1.37 Bn -5.18 Bn
4 Moderna 56.04 Bn 50.91 Bn 52.00 Mn -5.14 Bn
5 BeOne Medicines 42.05 Bn 36.95 Bn 1.53 Bn -5.10 Bn
6 Alnylam Pharmaceuticals 31.71 Bn 28.40 Bn 992.69 Mn -3.31 Bn
7 BioNTech SE 27.66 Bn 9.26 Bn 668.28 Mn -18.39 Bn
8 Insmed 27.50 Bn 26.33 Bn 358.27 Mn -1.16 Bn
9 Royalty Pharma 27.35 Bn 26.52 Bn - 2.12 Bn
10 Cyclerion Therapeutics 12.29 Mn 9.05 Mn - -3.24 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.24 Mn
Sep 30, 2025 -4.57 Mn
Jun 30, 2025 -3.01 Mn
Mar 31, 2025 -3.64 Mn
Dec 31, 2024 -3.23 Mn
Sep 30, 2024 -2.87 Mn
Jun 30, 2024 -4.59 Mn
Mar 31, 2024 -5.70 Mn
Dec 31, 2023 -7.57 Mn
Sep 30, 2023 -9.11 Mn
Jun 30, 2023 -5.64 Mn
Mar 31, 2023 -7.17 Mn
Dec 31, 2022 -13.38 Mn
Sep 30, 2022 -20.41 Mn
Jun 30, 2022 -30.32 Mn
Mar 31, 2022 -41.10 Mn
Dec 31, 2021 -53.96 Mn
Sep 30, 2021 -62.50 Mn
Jun 30, 2021 -70.39 Mn
Mar 31, 2021 -41.43 Mn