Cyclerion Therapeutics (CYCN) Enterprise Value (2019 - 2025)
Cyclerion Therapeutics (CYCN) recorded quarterly Enterprise Value of -$3.2 million in Q4 2025, up 29.07% quarter-over-quarter from -$4.6 million in Q3 2025, and little changed on a YoY basis from -$3.2 million in Q4 2024.
Cyclerion Therapeutics (CYCN) Enterprise Value (2019 - 2025) Analysis & Trends
Cyclerion Therapeutics' Enterprise Value history runs 7 years deep, the most recent figure standing at -$3.2 million for Q4 2025.
- In Q4 2025, Enterprise Value changed 0.25% year-over-year to -$3.2 million; the TTM figure through Dec 2025 stood at -$3.2 million (changed 0.25% YoY), while the FY2025 annual figure was -$3.2 million, changed 0.25% from the prior year.
- Enterprise Value was -$3.2 million for Q4 2025 at Cyclerion Therapeutics, up from -$4.6 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$2.9 million in Q3 2024 to a low of -$70.4 million in Q2 2021.
- Historically, Enterprise Value has averaged -$19.7 million across 5 years, with a median of -$7.4 million in 2023.
- The sharpest annual moves came in 2023 and 2025: Enterprise Value jumped 82.57% in 2023, then plunged 59.05% in 2025.
- A 5-year view of Enterprise Value shows it stood at -$54.0 million in 2021, then surged by 75.2% to -$13.4 million in 2022, then surged by 43.42% to -$7.6 million in 2023, then surged by 57.31% to -$3.2 million in 2024, then decreased by 0.25% to -$3.2 million in 2025.
- The last three Enterprise Value figures came in at -$3.2 million (Q4 2025), -$4.6 million (Q3 2025), and -$3.0 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | - |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | -2.77 Mn |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | -18.44 Mn |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | -584.73 Mn |
| 10 | Cyclerion Therapeutics | 11.50 Mn | 8.26 Mn | - | -3.24 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -3.24 Mn |
| Sep 30, 2025 | -4.57 Mn |
| Jun 30, 2025 | -3.01 Mn |
| Mar 31, 2025 | -3.64 Mn |
| Dec 31, 2024 | -3.23 Mn |
| Sep 30, 2024 | -2.87 Mn |
| Jun 30, 2024 | -4.59 Mn |
| Mar 31, 2024 | -5.70 Mn |
| Dec 31, 2023 | -7.57 Mn |
| Sep 30, 2023 | -9.11 Mn |
| Jun 30, 2023 | -5.64 Mn |
| Mar 31, 2023 | -7.17 Mn |
| Dec 31, 2022 | -13.38 Mn |
| Sep 30, 2022 | -20.41 Mn |
| Jun 30, 2022 | -30.32 Mn |
| Mar 31, 2022 | -41.13 Mn |
| Dec 31, 2021 | -53.96 Mn |
| Sep 30, 2021 | -62.50 Mn |
| Jun 30, 2021 | -70.39 Mn |
| Mar 31, 2021 | -41.43 Mn |