Cyclerion Therapeutics CYCN
NASDAQ CYCN
$3.81 -0.26 (-6.39%)
As of: Aug 21, 2026 · 11:02 AM EDT

Cyclerion Therapeutics (CYCN) EBITDA (2018 - 2025)

Cyclerion Therapeutics (CYCN) posted quarterly EBITDA of -$1.0 million for Q3 2025, up 10.82% year-over-year from -$907814.4 in Q3 2024, and up 39.83% quarter-over-quarter from -$1.7 million in Q2 2025.

Cyclerion Therapeutics (CYCN) EBITDA (2018 - 2025) Analysis & Trends

Cyclerion Therapeutics' EBITDA history runs 8 years deep, the most recent figure standing at -$1.0 million for Q3 2025.

  • In Q3 2025, EBITDA rose 10.82% year-over-year to -$1.0 million; the TTM figure through Sep 2025 stood at -$3.6 million (up 38.68% YoY), while the FY2024 annual figure was -$3.6 million, up 71.99% from the prior year.
  • EBITDA for Q3 2025 stood at -$1.0 million, up from -$1.7 million in the prior quarter.
  • The five-year high for EBITDA was $502000.0 in Q4 2024, with the low at -$16.2 million in Q2 2021.
  • The 5-year median for EBITDA is -$3.3 million (2023), against an average of -$5.9 million.
  • The sharpest annual moves came in 2023 and 2024: EBITDA slumped 33.13% in 2023, then surged 127.97% in 2024.
  • Cyclerion Therapeutics' EBITDA stood at -$14.3 million in 2021, then soared by 68.93% to -$4.5 million in 2022, then soared by 59.71% to -$1.8 million in 2023, then soared by 127.97% to $502000.0 in 2024, then sank by 300.4% to -$1.0 million in 2025.
  • Business Quant data shows CYCN's EBITDA at -$1.0 million in Q3 2025, -$1.7 million in Q2 2025, and -$1.5 million in Q1 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 140.14 Bn 132.29 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 87.02 Bn 79.03 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 65.30 Bn 60.12 Bn 1.37 Bn 493.00 Mn
4 Moderna 60.84 Bn 55.70 Bn 52.00 Mn -815.00 Mn
5 BeOne Medicines 42.15 Bn 37.06 Bn 1.53 Bn 325.05 Mn
6 Alnylam Pharmaceuticals 31.49 Bn 28.18 Bn 992.69 Mn 231.44 Mn
7 BioNTech SE 28.78 Bn 10.38 Bn 668.28 Mn -375.75 Mn
8 Insmed 27.55 Bn 26.39 Bn 358.27 Mn -1.55 Mn
9 Royalty Pharma 27.14 Bn 26.31 Bn - 133.12 Mn
10 Cyclerion Therapeutics 12.29 Mn 9.05 Mn - -

Historic Data

Download Data
DateValue
Sep 30, 2025 -1.01 Mn
Jun 30, 2025 -1.67 Mn
Mar 31, 2025 -1.46 Mn
Dec 31, 2024 502,000.00
Sep 30, 2024 -1.13 Mn
Jun 30, 2024 -1.38 Mn
Mar 31, 2024 -1.62 Mn
Dec 31, 2023 -1.80 Mn
Sep 30, 2023 -6.02 Mn
Jun 30, 2023 -1.87 Mn
Mar 31, 2023 -3.28 Mn
Dec 31, 2022 -4.46 Mn
Sep 30, 2022 -4.52 Mn
Jun 30, 2022 -13.43 Mn
Mar 31, 2022 -12.98 Mn
Dec 31, 2021 -14.34 Mn
Sep 30, 2021 -11.29 Mn
Jun 30, 2021 -16.18 Mn
Mar 31, 2021 -13.40 Mn
Dec 31, 2020 -19.22 Mn