Cyclerion Therapeutics (CYCN) EBITDA (2018 - 2025)
Cyclerion Therapeutics (CYCN) recorded quarterly EBITDA of -$976000.0 in Q3 2025, up 41.63% quarter-over-quarter from -$1.7 million in Q2 2025, and down 34.99% on a YoY basis from -$1.5 million in Q3 2024.
Cyclerion Therapeutics (CYCN) EBITDA (2018 - 2025) Analysis & Trends
Cyclerion Therapeutics' EBITDA history runs 8 years deep, the most recent figure standing at -$976000.0 for Q3 2025.
- In Q3 2025, EBITDA fell 34.99% year-over-year to -$976000.0; the TTM figure through Sep 2025 stood at -$3.6 million (up 33.65% YoY), while the FY2024 annual figure was -$3.6 million, up 71.99% from the prior year.
- EBITDA was -$976000.0 for Q3 2025 at Cyclerion Therapeutics, up from -$1.7 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of $502000.0 in Q4 2024 to a low of -$16.2 million in Q2 2021.
- Historically, EBITDA has averaged -$6.5 million across 5 years, with a median of -$4.5 million in 2022.
- The sharpest annual moves came in 2024 and 2025: EBITDA soared 127.97% in 2024, then slumped 34.99% in 2025.
- A 5-year view of EBITDA shows it stood at -$14.3 million in 2021, then jumped by 68.93% to -$4.5 million in 2022, then jumped by 59.71% to -$1.8 million in 2023, then jumped by 127.97% to $502000.0 in 2024, then slumped by 294.42% to -$976000.0 in 2025.
- The last three EBITDA figures came in at -$976000.0 (Q3 2025), -$1.7 million (Q2 2025), and -$1.4 million (Q1 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | - |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | -65.83 Mn |
| 10 | Cyclerion Therapeutics | 11.50 Mn | 8.26 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Sep 30, 2025 | -976,000.00 |
| Jun 30, 2025 | -1.67 Mn |
| Mar 31, 2025 | -1.43 Mn |
| Dec 31, 2024 | 502,000.00 |
| Sep 30, 2024 | -723,000.00 |
| Jun 30, 2024 | -1.32 Mn |
| Mar 31, 2024 | -1.55 Mn |
| Dec 31, 2023 | -1.80 Mn |
| Sep 30, 2023 | -6.02 Mn |
| Jun 30, 2023 | -4.18 Mn |
| Mar 31, 2023 | -6.95 Mn |
| Dec 31, 2022 | -4.46 Mn |
| Sep 30, 2022 | -10.50 Mn |
| Jun 30, 2022 | -13.43 Mn |
| Mar 31, 2022 | -12.98 Mn |
| Dec 31, 2021 | -14.34 Mn |
| Sep 30, 2021 | -11.29 Mn |
| Jun 30, 2021 | -16.18 Mn |
| Mar 31, 2021 | -13.40 Mn |
| Dec 31, 2020 | -19.23 Mn |