BioNTech SE (BNTX) EBITDA (2018 - 2025)
BioNTech SE (BNTX) posted EBITDA of -$375.8 million for Q4 2025, down 585.32% on a QoQ basis from -$54.8 million in Q3 2025, and down 336.63% year-over-year from $158.8 million in Q4 2024.
BioNTech SE (BNTX) has 8 years of EBITDA data on file, last reported at -$375.8 million in Q4 2025.
- In Q4 2025, EBITDA fell 336.63% year-over-year to -$375.8 million; the TTM figure through Dec 2025 stood at -$1.4 billion (down 50.58% YoY), while the FY2025 annual figure was -$1.6 billion, down 13.02% from the prior year.
- EBITDA declined to -$375.8 million in Q4 2025, from -$54.8 million in the prior quarter.
- Across five years, EBITDA topped out at $5.6 billion in Q3 2021 and bottomed at -$985.8 million in Q2 2024.
- A 5-year average of $1.5 billion and a median of $385.7 million in 2024 frame the typical range for EBITDA.
- Annual changes were most pronounced in 2021 — EBITDA surged 5574.02% — and 2025, when it sank 336.63%.
- Year by year, EBITDA stood at $5.4 billion in 2021, then tumbled by 37.51% to $3.4 billion in 2022, then slumped by 83.15% to $566.2 million in 2023, then sank by 71.95% to $158.8 million in 2024, then slumped by 336.63% to -$375.8 million in 2025.
- The last three EBITDA figures came in at -$375.8 million (Q4 2025), -$54.8 million (Q3 2025), and -$481.1 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 661.60 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 201.19 Mn |
| 10 | BioNTech SE | 27.66 Bn | 7.53 Bn | 668.28 Mn | -375.75 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -375.75 Mn |
| Sep 30, 2025 | -54.83 Mn |
| Jun 30, 2025 | -481.08 Mn |
| Mar 31, 2025 | -503.64 Mn |
| Dec 31, 2024 | 158.79 Mn |
| Sep 30, 2024 | 205.15 Mn |
| Jun 30, 2024 | -985.78 Mn |
| Mar 31, 2024 | -318.09 Mn |
| Dec 31, 2023 | 566.16 Mn |
| Sep 30, 2023 | 165.47 Mn |
| Jun 30, 2023 | -613.39 Mn |
| Mar 31, 2023 | 702.39 Mn |
| Dec 31, 2022 | 3.36 Bn |
| Sep 30, 2022 | 2.41 Bn |
| Jun 30, 2022 | 2.36 Bn |
| Mar 31, 2022 | 5.33 Bn |
| Dec 31, 2021 | 5.38 Bn |
| Sep 30, 2021 | 5.57 Bn |
| Jun 30, 2021 | 5.06 Bn |
| Mar 31, 2021 | 2.01 Bn |
| Dec 31, 2020 | 291,157.18 Bn |
| Sep 30, 2020 | 217.73 Mn |
| Jun 30, 2020 | 89.11 Mn |
| Mar 31, 2020 | 65.46 Mn |
| Dec 31, 2019 | -343.22 Mn |
| Sep 30, 2019 | 41.03 Mn |
| Jun 30, 2019 | 53.79 Mn |
| Mar 31, 2019 | 49.82 Mn |
| Dec 31, 2018 | 61,410.03 |
| Sep 30, 2018 | 25.16 |