Charles River Laboratories International (CRL) Operating Margin (2009 - 2025)

Charles River Laboratories International (CRL) recorded quarterly Operating Margin of 28.51% in Q4 2025, down 314.1% quarter-over-quarter from 13.32% in Q3 2025, and down 1178.0% on a YoY basis from 2.64% in Q4 2024.

Charles River Laboratories International (CRL) Operating Margin (2009 - 2025) Analysis & Trends

Charles River Laboratories International's Operating Margin history runs 17 years deep, the most recent figure standing at 28.51% for Q4 2025.

  • In Q4 2025, Operating Margin fell 1178.0% year-over-year to 28.51%; the TTM figure through Dec 2025 stood at 0.63% (down 499.0% YoY), while the FY2025 annual figure was 0.63%, down 499.0% from the prior year.
  • Operating Margin was 28.51% for Q4 2025 at Charles River Laboratories International, down from 13.32% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 19.26% in Q2 2022 to a low of 28.51% in Q4 2025.
  • Historically, Operating Margin has averaged 10.81% across 5 years, with a median of 14.84% in 2022.
  • The sharpest annual moves came in 2022 and 2024: Operating Margin jumped 422 bps in 2022, then tumbled 2984 bps in 2024.
  • A 5-year view of Operating Margin shows it stood at 19.09% in 2021, then retreated by 22 bps to 14.89% in 2022, then slipped by 12 bps to 13.12% in 2023, then plunged by 228 bps to 16.73% in 2024, then tumbled by 70 bps to 28.51% in 2025.
  • The last three Operating Margin figures came in at 28.51% (Q4 2025), 13.32% (Q3 2025), and 9.7% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn -3.71%
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 16.93%
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 22.58%
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 31.78%
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 21.74%
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 12.38%
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn -13.42%
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 19.16%
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 25.23%
10 Charles River Laboratories International 9.26 Bn 9.06 Bn 744.94 Mn -28.51%

Historic Data

Download Data
DateValue
Dec 27, 2025 -28.51%
Sep 27, 2025 13.32%
Jun 28, 2025 9.70%
Mar 29, 2025 7.59%
Dec 28, 2024 -16.73%
Sep 28, 2024 11.63%
Jun 29, 2024 14.78%
Mar 30, 2024 12.45%
Dec 30, 2023 13.12%
Sep 30, 2023 14.76%
Jul 1, 2023 15.56%
Apr 1, 2023 16.31%
Dec 31, 2022 14.89%
Sep 24, 2022 15.26%
Jun 25, 2022 19.26%
Mar 26, 2022 16.28%
Dec 25, 2021 19.09%
Sep 25, 2021 17.39%
Jun 26, 2021 15.04%
Mar 27, 2021 15.00%