Charles River Laboratories International (CRL) Gross Profit (2009 - 2025)

Charles River Laboratories International (CRL) recorded quarterly Gross Profit of $744.9 million in Q4 2025, up 24.84% quarter-over-quarter from $596.7 million in Q3 2025, and up 305.17% on a YoY basis from $183.9 million in Q4 2024.

Charles River Laboratories International (CRL) Gross Profit (2009 - 2025) Analysis & Trends

Charles River Laboratories International's Gross Profit history runs 17 years deep, the most recent figure standing at $744.9 million for Q4 2025.

  • In Q4 2025, Gross Profit rose 305.17% year-over-year to $744.9 million; the TTM figure through Dec 2025 stood at $2.2 billion (up 41.55% YoY), while the FY2025 annual figure was $3.4 billion, up 46.17% from the prior year.
  • Gross Profit was $744.9 million for Q4 2025 at Charles River Laboratories International, up from $596.7 million in the prior quarter.
  • In the past five years, Gross Profit ranged from a high of $1.9 billion in Q4 2021 to a low of -$363.1 million in Q4 2024.
  • Historically, Gross Profit has averaged $589.4 million across 5 years, with a median of $473.6 million in 2022.
  • The sharpest annual moves came in 2024 and 2025: Gross Profit tumbled 152.25% in 2024, then jumped 305.17% in 2025.
  • A 5-year view of Gross Profit shows it stood at $1.9 billion in 2021, then sank by 73.94% to $496.7 million in 2022, then jumped by 39.91% to $695.0 million in 2023, then slumped by 152.25% to -$363.1 million in 2024, then surged by 305.17% to $744.9 million in 2025.
  • The last three Gross Profit figures came in at $744.9 million (Q4 2025), $596.7 million (Q3 2025), and $447.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn
10 Charles River Laboratories International 9.26 Bn 9.06 Bn 744.94 Mn

Historic Data

Download Data
DateValue
Dec 27, 2025 744.94 Mn
Dec 27, 2025 744.94 Mn
Sep 27, 2025 596.74 Mn
Sep 27, 2025 596.74 Mn
Jun 28, 2025 447.26 Mn
Jun 28, 2025 447.26 Mn
Mar 29, 2025 406.74 Mn
Mar 29, 2025 406.74 Mn
Dec 28, 2024 -363.09 Mn
Dec 28, 2024 -363.09 Mn
Sep 28, 2024 871.86 Mn
Sep 28, 2024 871.86 Mn
Jun 29, 2024 448.73 Mn
Jun 29, 2024 448.73 Mn
Mar 30, 2024 593.65 Mn
Mar 30, 2024 593.65 Mn
Dec 30, 2023 694.96 Mn
Dec 30, 2023 694.96 Mn
Sep 30, 2023 361.84 Mn
Sep 30, 2023 361.84 Mn