Charles River Laboratories International (CRL) Gross Profit (2009 - 2025)
Charles River Laboratories International (CRL) recorded quarterly Gross Profit of $744.9 million in Q4 2025, up 24.84% quarter-over-quarter from $596.7 million in Q3 2025, and up 305.17% on a YoY basis from $183.9 million in Q4 2024.
Charles River Laboratories International (CRL) Gross Profit (2009 - 2025) Analysis & Trends
Charles River Laboratories International's Gross Profit history runs 17 years deep, the most recent figure standing at $744.9 million for Q4 2025.
- In Q4 2025, Gross Profit rose 305.17% year-over-year to $744.9 million; the TTM figure through Dec 2025 stood at $2.2 billion (up 41.55% YoY), while the FY2025 annual figure was $3.4 billion, up 46.17% from the prior year.
- Gross Profit was $744.9 million for Q4 2025 at Charles River Laboratories International, up from $596.7 million in the prior quarter.
- In the past five years, Gross Profit ranged from a high of $1.9 billion in Q4 2021 to a low of -$363.1 million in Q4 2024.
- Historically, Gross Profit has averaged $589.4 million across 5 years, with a median of $473.6 million in 2022.
- The sharpest annual moves came in 2024 and 2025: Gross Profit tumbled 152.25% in 2024, then jumped 305.17% in 2025.
- A 5-year view of Gross Profit shows it stood at $1.9 billion in 2021, then sank by 73.94% to $496.7 million in 2022, then jumped by 39.91% to $695.0 million in 2023, then slumped by 152.25% to -$363.1 million in 2024, then surged by 305.17% to $744.9 million in 2025.
- The last three Gross Profit figures came in at $744.9 million (Q4 2025), $596.7 million (Q3 2025), and $447.3 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn |
| 10 | Charles River Laboratories International | 9.26 Bn | 9.06 Bn | 744.94 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 27, 2025 | 744.94 Mn |
| Dec 27, 2025 | 744.94 Mn |
| Sep 27, 2025 | 596.74 Mn |
| Sep 27, 2025 | 596.74 Mn |
| Jun 28, 2025 | 447.26 Mn |
| Jun 28, 2025 | 447.26 Mn |
| Mar 29, 2025 | 406.74 Mn |
| Mar 29, 2025 | 406.74 Mn |
| Dec 28, 2024 | -363.09 Mn |
| Dec 28, 2024 | -363.09 Mn |
| Sep 28, 2024 | 871.86 Mn |
| Sep 28, 2024 | 871.86 Mn |
| Jun 29, 2024 | 448.73 Mn |
| Jun 29, 2024 | 448.73 Mn |
| Mar 30, 2024 | 593.65 Mn |
| Mar 30, 2024 | 593.65 Mn |
| Dec 30, 2023 | 694.96 Mn |
| Dec 30, 2023 | 694.96 Mn |
| Sep 30, 2023 | 361.84 Mn |
| Sep 30, 2023 | 361.84 Mn |