Charles River Laboratories International (CRL) Gross Profit (2009 - 2025)

Charles River Laboratories International (CRL) posted quarterly Gross Profit of $744.9 million for Q4 2025, up 305.17% year-over-year from $183.9 million in Q4 2024, and up 24.84% on a QoQ basis from $596.7 million in Q3 2025.

Charles River Laboratories International (CRL) Gross Profit (2009 - 2025) Analysis & Trends

Charles River Laboratories International (CRL) has reported Gross Profit for 17 consecutive years, with $744.9 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Gross Profit rose 305.17% year-over-year to $744.9 million; the TTM figure through Dec 2025 stood at $2.2 billion (up 41.55% YoY), while the FY2025 annual figure was $3.4 billion, up 46.17% from the prior year.
  • Gross Profit came in at $744.9 million for Q4 2025 at Charles River Laboratories International, up from $596.7 million in the prior quarter.
  • The five-year high for Gross Profit was $1.9 billion in Q4 2021, with the low at -$363.1 million in Q4 2024.
  • Average Gross Profit over 5 years is $589.4 million, with a median of $473.6 million recorded in 2022.
  • Across the five-year window, Gross Profit plunged 152.25% in 2024 and jumped 305.17% in 2025, its largest moves.
  • Year by year, Gross Profit stood at $1.9 billion in 2021, then slumped by 73.94% to $496.7 million in 2022, then jumped by 39.91% to $695.0 million in 2023, then tumbled by 152.25% to -$363.1 million in 2024, then surged by 305.17% to $744.9 million in 2025.
  • According to Business Quant data, Gross Profit over the past three periods registered $744.9 million, $596.7 million, and $447.3 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Waters 31,055.11 Bn 31,054.65 Bn 1.11 Bn
2 Thermo Fisher Scientific 191.02 Bn 187.77 Bn 7.74 Bn
3 Danaher 137.16 Bn 131.47 Bn 3.59 Bn
4 Idexx Laboratories 42.82 Bn 42.62 Bn 722.74 Mn
5 Natera 39.09 Bn 37.99 Bn 696.04 Mn
6 Agilent Technologies 37.61 Bn 35.81 Bn 990.00 Mn
7 Iqvia Holdings 34.23 Bn 32.25 Bn 1.36 Bn
8 Illumina 28.14 Bn 26.98 Bn 721.00 Mn
9 Mettler Toledo International 26.40 Bn 26.33 Bn 555.82 Mn
10 Charles River Laboratories International 11.36 Bn 11.15 Bn 744.94 Mn

Historic Data

Download Data
DateValue
Dec 27, 2025 744.94 Mn
Dec 27, 2025 744.94 Mn
Sep 27, 2025 596.74 Mn
Sep 27, 2025 596.74 Mn
Jun 28, 2025 447.26 Mn
Jun 28, 2025 447.26 Mn
Mar 29, 2025 406.74 Mn
Mar 29, 2025 406.74 Mn
Dec 28, 2024 -363.09 Mn
Dec 28, 2024 -363.09 Mn
Sep 28, 2024 871.86 Mn
Sep 28, 2024 871.86 Mn
Jun 29, 2024 448.73 Mn
Jun 29, 2024 448.73 Mn
Mar 30, 2024 593.65 Mn
Mar 30, 2024 593.65 Mn
Dec 30, 2023 694.96 Mn
Dec 30, 2023 694.96 Mn
Sep 30, 2023 361.84 Mn
Sep 30, 2023 361.84 Mn