Charles River Laboratories International (CRL) Operating Income (2009 - 2025)

Charles River Laboratories International (CRL) posted quarterly Operating Income of -$283.4 million for Q4 2025, down 69.03% year-over-year from -$915.2 million in Q4 2024, and down 311.84% quarter-over-quarter from $133.8 million in Q3 2025.

Charles River Laboratories International (CRL) Operating Income (2009 - 2025) Analysis & Trends

Charles River Laboratories International's Operating Income history runs 17 years deep, the most recent figure standing at -$283.4 million for Q4 2025.

  • In Q4 2025, Operating Income fell 69.03% year-over-year to -$283.4 million; the TTM figure through Dec 2025 stood at $25.2 million (down 88.93% YoY), while the FY2025 annual figure was $25.2 million, down 88.93% from the prior year.
  • Operating Income for Q4 2025 stood at -$283.4 million, down from $133.8 million in the prior quarter.
  • The five-year high for Operating Income was $187.4 million in Q2 2022, with the low at -$283.4 million in Q4 2025.
  • The 5-year median for Operating Income is $143.2 million (2021), against an average of $105.5 million.
  • The sharpest annual moves came in 2021 and 2024: Operating Income surged 79.18% in 2021, then slumped 226.15% in 2024.
  • Charles River Laboratories International's Operating Income stood at $172.8 million in 2021, then decreased by 5.21% to $163.8 million in 2022, then fell by 18.86% to $132.9 million in 2023, then plunged by 226.15% to -$167.7 million in 2024, then slumped by 69.03% to -$283.4 million in 2025.
  • Business Quant data shows CRL's Operating Income at -$283.4 million in Q4 2025, $133.8 million in Q3 2025, and $100.1 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Thermo Fisher Scientific 213.78 Bn 209.71 Bn 8.34 Bn 2.09 Bn
2 Danaher 139.83 Bn 135.48 Bn 3.61 Bn 1.13 Bn
3 Idexx Laboratories 45.99 Bn 45.79 Bn 779.09 Mn 425.57 Mn
4 Agilent Technologies 39.69 Bn 37.88 Bn 990.00 Mn 399.00 Mn
5 Iqvia Holdings 39.31 Bn 37.23 Bn 1.44 Bn 506.00 Mn
6 Natera 38.74 Bn 37.64 Bn 696.04 Mn -93.52 Mn
7 Illumina 29.94 Bn 28.77 Bn 770.00 Mn 245.00 Mn
8 Mettler Toledo International 28.55 Bn 28.50 Bn 650.22 Mn 328.45 Mn
9 Quest Diagnostics 26.18 Bn 25.55 Bn 1.03 Bn 459.00 Mn
10 Charles River Laboratories International 12.74 Bn 12.53 Bn 1.81 Bn -283.44 Mn

Historic Data

Download Data
DateValue
Dec 27, 2025 -283.44 Mn
Sep 27, 2025 133.80 Mn
Jun 28, 2025 100.13 Mn
Mar 29, 2025 74.67 Mn
Dec 28, 2024 -167.69 Mn
Sep 28, 2024 117.41 Mn
Jun 29, 2024 151.65 Mn
Mar 30, 2024 125.98 Mn
Dec 30, 2023 132.92 Mn
Sep 30, 2023 151.50 Mn
Jul 1, 2023 164.95 Mn
Apr 1, 2023 167.89 Mn
Dec 31, 2022 163.81 Mn
Sep 24, 2022 150.98 Mn
Jun 25, 2022 187.41 Mn
Mar 26, 2022 148.78 Mn
Dec 25, 2021 172.81 Mn
Sep 25, 2021 155.80 Mn
Jun 26, 2021 137.55 Mn
Mar 27, 2021 123.70 Mn