Growth Metrics

Caribou Biosciences (CRBU) Operating Expenses (2020 - 2026)

Caribou Biosciences (CRBU) reported Operating Expenses of $28.7 million for Q1 2026, down 36.65% year-over-year from $45.3 million in Q1 2025, and down 11.47% on a QoQ basis from $32.4 million in Q4 2025.

Caribou Biosciences (CRBU) has 7 years of Operating Expenses data on file, last reported at $28.7 million in Q1 2026.

  • Quarterly Operating Expenses fell 36.65% year-over-year to $28.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $142.9 million (down 17.6% YoY) and the FY2025 annual result came in at $159.5 million, down 9.69% from the prior year.
  • Operating Expenses retreated to $28.7 million in Q1 2026 per CRBU's latest filing, from $32.4 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $50.2 million in Q2 2025 and bottomed at $23.5 million in Q1 2022.
  • The 5-year median for Operating Expenses is $36.6 million (2023), against an average of $37.4 million.
  • The widest annual swing landed in 2022, when Operating Expenses surged 87.06%; it then plunged 36.65% in 2026.
  • Tracing CRBU's Operating Expenses over 5 years: stood at $34.3 million in 2022, then grew by 19.64% to $41.0 million in 2023, then declined by 0.12% to $41.0 million in 2024, then retreated by 20.9% to $32.4 million in 2025, then slipped by 11.47% to $28.7 million in 2026.
  • Per Business Quant, the three latest CRBU Operating Expenses figures stand at $28.7 million (Q1 2026), $32.4 million (Q4 2025), and $31.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Caribou Biosciences 232.46 Mn 114.84 Mn - 28.68 Mn

Historic Data

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DateValue
Mar 31, 2026 28.68 Mn
Dec 31, 2025 32.39 Mn
Sep 30, 2025 31.60 Mn
Jun 30, 2025 50.25 Mn
Mar 31, 2025 45.27 Mn
Dec 31, 2024 40.95 Mn
Sep 30, 2024 40.26 Mn
Jun 30, 2024 46.97 Mn
Mar 31, 2024 48.43 Mn
Dec 31, 2023 41.00 Mn
Sep 30, 2023 38.30 Mn
Jun 30, 2023 36.62 Mn
Mar 31, 2023 34.62 Mn
Dec 31, 2022 34.27 Mn
Sep 30, 2022 29.84 Mn
Jun 30, 2022 32.62 Mn
Mar 31, 2022 23.52 Mn
Dec 31, 2021 22.96 Mn
Sep 30, 2021 22.59 Mn
Jun 30, 2021 17.44 Mn
Mar 31, 2021 14.76 Mn
Dec 31, 2020 16.20 Mn
Sep 30, 2020 9.43 Mn
Jun 30, 2020 10.73 Mn
Mar 31, 2020 12.13 Mn