Caribou Biosciences (CRBU) Operating Expenses (2020 - 2026)
Caribou Biosciences (CRBU) reported Operating Expenses of $28.7 million for Q1 2026, down 36.65% year-over-year from $45.3 million in Q1 2025, and down 11.47% on a QoQ basis from $32.4 million in Q4 2025.
Caribou Biosciences (CRBU) has 7 years of Operating Expenses data on file, last reported at $28.7 million in Q1 2026.
- Quarterly Operating Expenses fell 36.65% year-over-year to $28.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $142.9 million (down 17.6% YoY) and the FY2025 annual result came in at $159.5 million, down 9.69% from the prior year.
- Operating Expenses retreated to $28.7 million in Q1 2026 per CRBU's latest filing, from $32.4 million in the prior quarter.
- Across five years, Operating Expenses topped out at $50.2 million in Q2 2025 and bottomed at $23.5 million in Q1 2022.
- The 5-year median for Operating Expenses is $36.6 million (2023), against an average of $37.4 million.
- The widest annual swing landed in 2022, when Operating Expenses surged 87.06%; it then plunged 36.65% in 2026.
- Tracing CRBU's Operating Expenses over 5 years: stood at $34.3 million in 2022, then grew by 19.64% to $41.0 million in 2023, then declined by 0.12% to $41.0 million in 2024, then retreated by 20.9% to $32.4 million in 2025, then slipped by 11.47% to $28.7 million in 2026.
- Per Business Quant, the three latest CRBU Operating Expenses figures stand at $28.7 million (Q1 2026), $32.4 million (Q4 2025), and $31.6 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.97 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 4.33 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -138.30 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 15.76 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.85 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 2.96 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 898.54 Mn |
| 10 | Caribou Biosciences | 232.46 Mn | 114.84 Mn | - | 28.68 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 28.68 Mn |
| Dec 31, 2025 | 32.39 Mn |
| Sep 30, 2025 | 31.60 Mn |
| Jun 30, 2025 | 50.25 Mn |
| Mar 31, 2025 | 45.27 Mn |
| Dec 31, 2024 | 40.95 Mn |
| Sep 30, 2024 | 40.26 Mn |
| Jun 30, 2024 | 46.97 Mn |
| Mar 31, 2024 | 48.43 Mn |
| Dec 31, 2023 | 41.00 Mn |
| Sep 30, 2023 | 38.30 Mn |
| Jun 30, 2023 | 36.62 Mn |
| Mar 31, 2023 | 34.62 Mn |
| Dec 31, 2022 | 34.27 Mn |
| Sep 30, 2022 | 29.84 Mn |
| Jun 30, 2022 | 32.62 Mn |
| Mar 31, 2022 | 23.52 Mn |
| Dec 31, 2021 | 22.96 Mn |
| Sep 30, 2021 | 22.59 Mn |
| Jun 30, 2021 | 17.44 Mn |
| Mar 31, 2021 | 14.76 Mn |
| Dec 31, 2020 | 16.20 Mn |
| Sep 30, 2020 | 9.43 Mn |
| Jun 30, 2020 | 10.73 Mn |
| Mar 31, 2020 | 12.13 Mn |