CareDx (CDNA) Operating Margin (2013 - 2026)
CareDx's Operating Margin came in at 5.82% for Q3 2026, up 6.07 percentage points from -0.25% a year earlier but down 79.99 percentage points from the prior quarter.
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Analysis
CareDx (CDNA) Operating Margin (2013 - 2026) Analysis & Trends
Over the trailing twelve months to Sep 30, 2026, CareDx reported Operating Margin of 23.42%, up 6.76 percentage points year-over-year; for FY2025, it was -8.10%, down 20.32 percentage points from FY2024.
- Operating Margin carries a five-year change of +3.62 percentage points (FY2020 to FY2025).
- Going back by year, Operating Margin was 12.21% in FY2024 (+84.76 pp), -72.55% in FY2023 (-48.55 pp), -24.00% in FY2022 (-13.97 pp) and -10.03% in FY2021 (+1.69 pp).
- The five-year range for quarterly Operating Margin is -187.03% (Q4 2023) to 97.46% (Q4 2024).
- Year-over-year, Operating Margin has increased for three consecutive quarters, with an average year-over-year change of +41.24 percentage points over the last eight quarters.
- The fastest year-over-year change in Operating Margin over five years came in Q4 2024 (a gain of 284.49 percentage points), and the weakest in Q4 2023 (a drop of 163.82 percentage points).
- Business Quant data shows CDNA's Operating Margin at 85.81% (Q2 2026), 1.02% (Q1 2026) and -5.57% (Q4 2025) in the three quarters before Q3 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 106.13 Bn | 102.23 Bn | - | - |
| 2 | Natera | 44.93 Bn | 40.56 Bn | 513.47 Mn | -8.60% |
| 3 | Labcorp Holdings | 29.97 Bn | 28.06 Bn | 1.11 Bn | 10.55% |
| 4 | Quest Diagnostics | 28.09 Bn | 25.85 Bn | 1.04 Bn | 15.47% |
| 5 | Tenet Healthcare | 22.72 Bn | 12.03 Bn | - | 31.08% |
| 6 | Guardant Health | 20.11 Bn | 15.73 Bn | 236.15 Mn | -36.78% |
| 7 | BrightSpring Health Services | 13.90 Bn | 11.66 Bn | 518.55 Mn | 3.81% |
| 8 | Tempus AI | 13.80 Bn | 10.95 Bn | 266.70 Mn | -13.82% |
| 9 | Encompass Health | 13.52 Bn | 13.15 Bn | - | - |
| 10 | CareDx | 4.09 Bn | 3.10 Bn | 99.08 Mn | 5.82% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 5.82% |
| Jun 30, 2026 | 85.81% |
| Mar 31, 2026 | 1.02% |
| Dec 31, 2025 | -5.57% |
| Sep 30, 2025 | -0.25% |
| Jun 30, 2025 | -12.83% |
| Mar 31, 2025 | -15.79% |
| Dec 31, 2024 | 97.46% |
| Sep 30, 2024 | -16.55% |
| Jun 30, 2024 | -7.94% |
| Mar 31, 2024 | -31.32% |
| Dec 31, 2023 | -187.03% |
| Sep 30, 2023 | -42.84% |
| Jun 30, 2023 | -39.29% |
| Mar 31, 2023 | -31.48% |
| Dec 31, 2022 | -23.21% |
| Sep 30, 2022 | -21.85% |
| Jun 30, 2022 | -26.94% |
| Mar 31, 2022 | -23.99% |
| Dec 31, 2021 | -19.44% |
API Access
CareDx Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CDNA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CDNA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CDNA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();