Growth Metrics

CareDx (CDNA) Operating Margin (2016 - 2025)

CareDx (CDNA) has disclosed Operating Margin for 13 consecutive years, with 5.57% as the latest value for Q4 2025.

  • Quarterly Operating Margin fell 10303.0% to 5.57% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 8.1% through Dec 2025, down 2032.0% year-over-year, with the annual reading at 8.1% for FY2025, 2032.0% down from the prior year.
  • Operating Margin hit 5.57% in Q4 2025 for CareDx, down from 0.25% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 97.46% in Q4 2024 to a low of 187.03% in Q4 2023.
  • Historically, Operating Margin has averaged 21.4% across 5 years, with a median of 18.0% in 2021.
  • Biggest five-year swings in Operating Margin: crashed -16382bps in 2023 and later surged 28449bps in 2024.
  • Year by year, Operating Margin stood at 19.44% in 2021, then decreased by -19bps to 23.21% in 2022, then plummeted by -706bps to 187.03% in 2023, then soared by 152bps to 97.46% in 2024, then tumbled by -106bps to 5.57% in 2025.
  • Business Quant data shows Operating Margin for CDNA at 5.57% in Q4 2025, 0.25% in Q3 2025, and 12.83% in Q2 2025.