CareDx (CDNA) Operating Margin (2013 - 2026)
CareDx's (CDNA) quarterly Operating Margin came in at 85.81% in Q2 2026, up 9864.0% year-over-year from 0.86% in Q2 2025, and up 8330.46% quarter-over-quarter from 1.02% in Q1 2026.
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CareDx (CDNA) Operating Margin (2013 - 2026) Analysis & Trends
CareDx has disclosed Operating Margin across 14 years of filings, most recently posting 85.81% for Q2 2026.
- In Q2 2026, Operating Margin rose 9864.0% year-over-year to 85.81%; the TTM figure through Jun 2026 stood at 23.61% (up 1006.0% YoY), while the FY2025 annual figure was 8.1%, down 2032.0% from the prior year.
- Operating Margin came in at 85.81% for Q2 2026 at CareDx, up from 1.02% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 97.46% in Q4 2024 to a low of 187.03% in Q4 2023.
- Average Operating Margin over 5 years is 16.81%, with a median of 19.2% recorded in 2022.
- Year-over-year, Operating Margin sank 16382 bps in 2023 and jumped 28449 bps in 2024.
- Over 5 years, Operating Margin stood at 23.21% in 2022, then slumped by 706 bps to 187.03% in 2023, then jumped by 152 bps to 97.46% in 2024, then slumped by 106 bps to 5.57% in 2025, then jumped by 1640 bps to 85.81% in 2026.
- Per Business Quant data, the three most recent Operating Margin figures were 85.81% in Q2 2026, 1.02% in Q1 2026, and 5.57% in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Natera | 53.05 Bn | 51.95 Bn | 486.15 Mn | -10.07% |
| 2 | Quest Diagnostics | 27.19 Bn | 26.87 Bn | 1.03 Bn | 15.08% |
| 3 | Labcorp Holdings | 25.93 Bn | 25.81 Bn | 1.11 Bn | 12.10% |
| 4 | Guardant Health | 23.97 Bn | 22.91 Bn | 219.03 Mn | -38.55% |
| 5 | Tempus AI | 13.64 Bn | 12.82 Bn | 274.25 Mn | -19.85% |
| 6 | Caris Life Sciences | 8.47 Bn | 7.68 Bn | 182.38 Mn | 10.21% |
| 7 | Sotera Health | 5.35 Bn | 4.99 Bn | 177.96 Mn | 34.17% |
| 8 | BillionToOne | 4.96 Bn | 4.41 Bn | 77.11 Mn | 5.03% |
| 9 | Adaptive Biotechnologies | 4.55 Bn | 4.21 Bn | 51.39 Mn | -22.04% |
| 10 | CareDx | 2.77 Bn | 2.40 Bn | 116.03 Mn | 85.81% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 85.81% |
| Mar 31, 2026 | 1.02% |
| Dec 31, 2025 | -5.57% |
| Sep 30, 2025 | -0.25% |
| Jun 30, 2025 | -12.83% |
| Mar 31, 2025 | -15.79% |
| Dec 31, 2024 | 97.46% |
| Sep 30, 2024 | -16.55% |
| Jun 30, 2024 | -7.94% |
| Mar 31, 2024 | -31.32% |
| Dec 31, 2023 | -187.03% |
| Sep 30, 2023 | -42.84% |
| Jun 30, 2023 | -39.29% |
| Mar 31, 2023 | -31.48% |
| Dec 31, 2022 | -23.21% |
| Sep 30, 2022 | -21.85% |
| Jun 30, 2022 | -26.94% |
| Mar 31, 2022 | -23.99% |
| Dec 31, 2021 | -19.44% |
| Sep 30, 2021 | -11.55% |