BioNTech SE (BNTX) Operating Expenses (2018 - 2025)

BioNTech SE (BNTX) reported Operating Expenses of -$784.6 million for Q4 2025, down 1.61% on a YoY basis from -$797.4 million in Q4 2024, and up 2.17% sequentially from -$802.0 million in Q3 2025.

BioNTech SE (BNTX) Operating Expenses (2018 - 2025) Analysis & Trends

BioNTech SE (BNTX) has 8 years of Operating Expenses data on file, last reported at -$784.6 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses fell 1.61% year-over-year to -$784.6 million; the trailing twelve-month figure through Dec 2025 stood at -$3.0 billion (up 1.74% YoY), and the FY2025 full-year result was -$3.0 billion, up 0.57% from the prior year.
  • Operating Expenses grew to -$784.6 million in Q4 2025, from -$802.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of -$299.7 million in Q2 2021 to a low of -$813.6 million in Q2 2024.
  • A 5-year average of -$600.6 million and a median of -$653.9 million in 2022 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses tumbled 131816999.25% in 2021 and climbed 12.79% in 2025, its largest moves.
  • Tracing BNTX's Operating Expenses over 5 years: stood at -$460.3 million in 2021, then tumbled by 39.56% to -$642.4 million in 2022, then slipped by 17.58% to -$755.4 million in 2023, then retreated by 2.22% to -$772.2 million in 2024, then declined by 1.61% to -$784.6 million in 2025.
  • Business Quant data shows BNTX's Operating Expenses at -$784.6 million in Q4 2025, -$802.0 million in Q3 2025, and -$709.5 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 BioNTech SE 21.56 Bn 21.56 Bn 668.28 Mn -784.57 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -784.57 Mn
Sep 30, 2025 -801.97 Mn
Jun 30, 2025 -709.51 Mn
Mar 31, 2025 -665.32 Mn
Dec 31, 2024 -772.17 Mn
Sep 30, 2024 -749.75 Mn
Jun 30, 2024 -813.59 Mn
Mar 31, 2024 -678.43 Mn
Dec 31, 2023 -755.42 Mn
Sep 30, 2023 -693.43 Mn
Jun 30, 2023 -537.06 Mn
Mar 31, 2023 -478.50 Mn
Dec 31, 2022 -642.45 Mn
Sep 30, 2022 -486.79 Mn
Jun 30, 2022 -565.11 Mn
Mar 31, 2022 -422.67 Mn
Dec 31, 2021 -460.33 Mn
Sep 30, 2021 -387.51 Mn
Jun 30, 2021 -299.74 Mn
Mar 31, 2021 -307.71 Mn