BioNTech SE (BNTX) Operating Expenses (2018 - 2025)
BioNTech SE (BNTX) reported Operating Expenses of -$784.6 million for Q4 2025, down 1.61% on a YoY basis from -$797.4 million in Q4 2024, and up 2.17% sequentially from -$802.0 million in Q3 2025.
BioNTech SE (BNTX) Operating Expenses (2018 - 2025) Analysis & Trends
BioNTech SE (BNTX) has 8 years of Operating Expenses data on file, last reported at -$784.6 million in Q4 2025.
- For the quarter ending Q4 2025, Operating Expenses fell 1.61% year-over-year to -$784.6 million; the trailing twelve-month figure through Dec 2025 stood at -$3.0 billion (up 1.74% YoY), and the FY2025 full-year result was -$3.0 billion, up 0.57% from the prior year.
- Operating Expenses grew to -$784.6 million in Q4 2025, from -$802.0 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of -$299.7 million in Q2 2021 to a low of -$813.6 million in Q2 2024.
- A 5-year average of -$600.6 million and a median of -$653.9 million in 2022 frame the typical range for Operating Expenses.
- Across the five-year window, Operating Expenses tumbled 131816999.25% in 2021 and climbed 12.79% in 2025, its largest moves.
- Tracing BNTX's Operating Expenses over 5 years: stood at -$460.3 million in 2021, then tumbled by 39.56% to -$642.4 million in 2022, then slipped by 17.58% to -$755.4 million in 2023, then retreated by 2.22% to -$772.2 million in 2024, then declined by 1.61% to -$784.6 million in 2025.
- Business Quant data shows BNTX's Operating Expenses at -$784.6 million in Q4 2025, -$802.0 million in Q3 2025, and -$709.5 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | BioNTech SE | 21.56 Bn | 21.56 Bn | 668.28 Mn | -784.57 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -784.57 Mn |
| Sep 30, 2025 | -801.97 Mn |
| Jun 30, 2025 | -709.51 Mn |
| Mar 31, 2025 | -665.32 Mn |
| Dec 31, 2024 | -772.17 Mn |
| Sep 30, 2024 | -749.75 Mn |
| Jun 30, 2024 | -813.59 Mn |
| Mar 31, 2024 | -678.43 Mn |
| Dec 31, 2023 | -755.42 Mn |
| Sep 30, 2023 | -693.43 Mn |
| Jun 30, 2023 | -537.06 Mn |
| Mar 31, 2023 | -478.50 Mn |
| Dec 31, 2022 | -642.45 Mn |
| Sep 30, 2022 | -486.79 Mn |
| Jun 30, 2022 | -565.11 Mn |
| Mar 31, 2022 | -422.67 Mn |
| Dec 31, 2021 | -460.33 Mn |
| Sep 30, 2021 | -387.51 Mn |
| Jun 30, 2021 | -299.74 Mn |
| Mar 31, 2021 | -307.71 Mn |