BioNTech SE (BNTX) Operating Expenses (2018 - 2025)
BioNTech SE's (BNTX) quarterly Operating Expenses came in at -$784.6 million in Q4 2025, down 1.61% year-on-year from -$797.4 million in Q4 2024, and up 2.17% quarter-over-quarter from -$802.0 million in Q3 2025.
BioNTech SE (BNTX) Operating Expenses (2018 - 2025) Analysis & Trends
BioNTech SE has disclosed Operating Expenses across 8 years of filings, most recently posting -$784.6 million for Q4 2025.
- Operating Expenses for Q4 2025 came in at -$784.6 million, down 1.61% year-over-year; the trailing twelve-month figure through Dec 2025 was -$3.0 billion (up 1.74% YoY), and the FY2025 annual result was -$3.0 billion, up 0.57% from the prior year.
- Operating Expenses came in at -$784.6 million for Q4 2025 at BioNTech SE, up from -$802.0 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of -$299.7 million in Q2 2021 to a low of -$813.6 million in Q2 2024.
- The 5-year median for Operating Expenses is -$653.9 million (2022), against an average of -$600.6 million.
- Across the five-year window, Operating Expenses slumped 1511.72% in 2021 and climbed 12.79% in 2025, its largest moves.
- BioNTech SE's Operating Expenses stood at -$460.3 million in 2021, then slumped by 39.56% to -$642.4 million in 2022, then dropped by 17.58% to -$755.4 million in 2023, then decreased by 2.22% to -$772.2 million in 2024, then fell by 1.61% to -$784.6 million in 2025.
- The last three Operating Expenses figures came in at -$784.6 million (Q4 2025), -$802.0 million (Q3 2025), and -$709.5 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | BioNTech SE | 27.38 Bn | 10.07 Bn | 668.28 Mn | -784.57 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -784.57 Mn |
| Sep 30, 2025 | -801.97 Mn |
| Jun 30, 2025 | -709.51 Mn |
| Mar 31, 2025 | -665.32 Mn |
| Dec 31, 2024 | -772.17 Mn |
| Sep 30, 2024 | -749.75 Mn |
| Jun 30, 2024 | -813.59 Mn |
| Mar 31, 2024 | -678.43 Mn |
| Dec 31, 2023 | -755.42 Mn |
| Sep 30, 2023 | -693.43 Mn |
| Jun 30, 2023 | -537.06 Mn |
| Mar 31, 2023 | -478.50 Mn |
| Dec 31, 2022 | -642.45 Mn |
| Sep 30, 2022 | -486.79 Mn |
| Jun 30, 2022 | -565.11 Mn |
| Mar 31, 2022 | -422.67 Mn |
| Dec 31, 2021 | -460.33 Mn |
| Sep 30, 2021 | -387.51 Mn |
| Jun 30, 2021 | -299.74 Mn |
| Mar 31, 2021 | -307.71 Mn |