BioNTech SE (BNTX) Operating Expenses (2018 - 2025)
BioNTech SE (BNTX) posted Operating Expenses of -$784.6 million for Q4 2025, up 2.17% sequentially from -$802.0 million in Q3 2025, and down 1.61% YoY from -$797.4 million in Q4 2024.
BioNTech SE (BNTX) Operating Expenses (2018 - 2025) Analysis & Trends
BioNTech SE has reported Operating Expenses for 8 years, with the latest figure at -$784.6 million in Q4 2025.
- Quarterly Operating Expenses fell 1.61% year-over-year to -$784.6 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$3.0 billion (up 1.74% YoY) and the FY2025 annual result came in at $3.0 billion, down 0.57% from the prior year.
- Operating Expenses grew to -$784.6 million in Q4 2025 per BNTX's latest filing, from -$802.0 million in the prior quarter.
- Over five years, Operating Expenses peaked at -$299.7 million in Q2 2021 and troughed at -$813.6 million in Q2 2024.
- A 5-year average of -$600.6 million and a median of -$653.9 million in 2022 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2021 and 2025: Operating Expenses sank 131816999.25% in 2021, then increased 12.79% in 2025.
- Over 5 years, Operating Expenses stood at -$460.3 million in 2021, then slumped by 39.56% to -$642.4 million in 2022, then fell by 17.58% to -$755.4 million in 2023, then dropped by 2.22% to -$772.2 million in 2024, then decreased by 1.61% to -$784.6 million in 2025.
- According to Business Quant data, Operating Expenses over the past three periods registered -$784.6 million, -$802.0 million, and -$709.5 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | BioNTech SE | 23.54 Bn | 5.15 Bn | 668.28 Mn | -784.57 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -784.57 Mn |
| Sep 30, 2025 | -801.97 Mn |
| Jun 30, 2025 | -709.51 Mn |
| Mar 31, 2025 | -665.32 Mn |
| Dec 31, 2024 | -772.17 Mn |
| Sep 30, 2024 | -749.75 Mn |
| Jun 30, 2024 | -813.59 Mn |
| Mar 31, 2024 | -678.43 Mn |
| Dec 31, 2023 | -755.42 Mn |
| Sep 30, 2023 | -693.43 Mn |
| Jun 30, 2023 | -537.06 Mn |
| Mar 31, 2023 | -478.50 Mn |
| Dec 31, 2022 | -642.45 Mn |
| Sep 30, 2022 | -486.79 Mn |
| Jun 30, 2022 | -565.11 Mn |
| Mar 31, 2022 | -422.67 Mn |
| Dec 31, 2021 | -460.33 Mn |
| Sep 30, 2021 | -387.51 Mn |
| Jun 30, 2021 | -299.74 Mn |
| Mar 31, 2021 | -307.71 Mn |