Bicycle Therapeutics (BCYC) Operating Expenses (2018 - 2026)
Bicycle Therapeutics (BCYC) posted Operating Expenses of $66.4 million for Q1 2026, down 8.66% on a QoQ basis from $72.7 million in Q4 2025, and down 17.23% year-over-year from $80.2 million in Q1 2025.
Bicycle Therapeutics (BCYC) Operating Expenses (2018 - 2026) Analysis & Trends
Bicycle Therapeutics' Operating Expenses history runs 9 years deep, the most recent figure standing at $66.4 million for Q1 2026.
- Quarterly Operating Expenses fell 17.23% year-over-year to $66.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $305.8 million (up 11.59% YoY) and the FY2025 annual result came in at $319.7 million, up 30.39% from the prior year.
- Operating Expenses was $66.4 million for Q1 2026 at Bicycle Therapeutics, down from $72.7 million in the prior quarter.
- Across five years, Operating Expenses topped out at $89.5 million in Q2 2025 and bottomed at $31.2 million in Q1 2022.
- A 5-year average of $57.6 million and a median of $56.1 million in 2023 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2022 — Operating Expenses surged 76.08% — and 2026, when it fell 17.23%.
- Bicycle Therapeutics' Operating Expenses stood at $35.4 million in 2022, then jumped by 68.28% to $59.6 million in 2023, then grew by 19.82% to $71.4 million in 2024, then climbed by 1.81% to $72.7 million in 2025, then slipped by 8.66% to $66.4 million in 2026.
- Business Quant data shows BCYC's Operating Expenses at $66.4 million in Q1 2026, $72.7 million in Q4 2025, and $77.3 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 1.10 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.78 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 2.89 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 445.22 Mn |
| 10 | Bicycle Therapeutics | 289.88 Mn | 289.88 Mn | - | 66.37 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 66.37 Mn |
| Dec 31, 2025 | 72.66 Mn |
| Sep 30, 2025 | 77.29 Mn |
| Jun 30, 2025 | 89.52 Mn |
| Mar 31, 2025 | 80.18 Mn |
| Dec 31, 2024 | 71.37 Mn |
| Sep 30, 2024 | 66.52 Mn |
| Jun 30, 2024 | 56.01 Mn |
| Mar 31, 2024 | 51.25 Mn |
| Dec 31, 2023 | 59.57 Mn |
| Sep 30, 2023 | 56.15 Mn |
| Jun 30, 2023 | 54.51 Mn |
| Mar 31, 2023 | 46.70 Mn |
| Dec 31, 2022 | 35.40 Mn |
| Sep 30, 2022 | 32.80 Mn |
| Jun 30, 2022 | 31.68 Mn |
| Mar 31, 2022 | 31.24 Mn |
| Dec 31, 2021 | 21.80 Mn |
| Sep 30, 2021 | 18.63 Mn |
| Jun 30, 2021 | 19.06 Mn |