Bicycle Therapeutics (BCYC) Operating Expenses (2018 - 2026)

Bicycle Therapeutics (BCYC) posted Operating Expenses of $66.4 million for Q1 2026, down 8.66% on a QoQ basis from $72.7 million in Q4 2025, and down 17.23% year-over-year from $80.2 million in Q1 2025.

Bicycle Therapeutics (BCYC) Operating Expenses (2018 - 2026) Analysis & Trends

Bicycle Therapeutics' Operating Expenses history runs 9 years deep, the most recent figure standing at $66.4 million for Q1 2026.

  • Quarterly Operating Expenses fell 17.23% year-over-year to $66.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $305.8 million (up 11.59% YoY) and the FY2025 annual result came in at $319.7 million, up 30.39% from the prior year.
  • Operating Expenses was $66.4 million for Q1 2026 at Bicycle Therapeutics, down from $72.7 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $89.5 million in Q2 2025 and bottomed at $31.2 million in Q1 2022.
  • A 5-year average of $57.6 million and a median of $56.1 million in 2023 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2022 — Operating Expenses surged 76.08% — and 2026, when it fell 17.23%.
  • Bicycle Therapeutics' Operating Expenses stood at $35.4 million in 2022, then jumped by 68.28% to $59.6 million in 2023, then grew by 19.82% to $71.4 million in 2024, then climbed by 1.81% to $72.7 million in 2025, then slipped by 8.66% to $66.4 million in 2026.
  • Business Quant data shows BCYC's Operating Expenses at $66.4 million in Q1 2026, $72.7 million in Q4 2025, and $77.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Bicycle Therapeutics 289.88 Mn 289.88 Mn - 66.37 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 66.37 Mn
Dec 31, 2025 72.66 Mn
Sep 30, 2025 77.29 Mn
Jun 30, 2025 89.52 Mn
Mar 31, 2025 80.18 Mn
Dec 31, 2024 71.37 Mn
Sep 30, 2024 66.52 Mn
Jun 30, 2024 56.01 Mn
Mar 31, 2024 51.25 Mn
Dec 31, 2023 59.57 Mn
Sep 30, 2023 56.15 Mn
Jun 30, 2023 54.51 Mn
Mar 31, 2023 46.70 Mn
Dec 31, 2022 35.40 Mn
Sep 30, 2022 32.80 Mn
Jun 30, 2022 31.68 Mn
Mar 31, 2022 31.24 Mn
Dec 31, 2021 21.80 Mn
Sep 30, 2021 18.63 Mn
Jun 30, 2021 19.06 Mn