Bicycle Therapeutics (BCYC) Operating Expenses (2018 - 2026)

Bicycle Therapeutics (BCYC) reported Operating Expenses of $66.4 million for Q1 2026, down 17.23% on a YoY basis from $80.2 million in Q1 2025, and down 8.66% quarter-over-quarter from $72.7 million in Q4 2025.

Bicycle Therapeutics (BCYC) Operating Expenses (2018 - 2026) Analysis & Trends

Bicycle Therapeutics has reported Operating Expenses for 9 years, with the latest figure at $66.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses fell 17.23% year-over-year to $66.4 million; the trailing twelve-month figure through Mar 2026 stood at $305.8 million (up 11.59% YoY), and the FY2025 full-year result was $319.7 million, up 30.39% from the prior year.
  • Operating Expenses for Q1 2026 stood at $66.4 million, down from $72.7 million in the prior quarter.
  • The five-year high for Operating Expenses was $89.5 million in Q2 2025, with the low at $31.2 million in Q1 2022.
  • Historically, Operating Expenses has averaged $57.6 million across 5 years, with a median of $56.1 million in 2023.
  • Annual changes were most pronounced in 2022 — Operating Expenses surged 76.08% — and 2026, when it slipped 17.23%.
  • Bicycle Therapeutics' Operating Expenses stood at $35.4 million in 2022, then surged by 68.28% to $59.6 million in 2023, then advanced by 19.82% to $71.4 million in 2024, then gained by 1.81% to $72.7 million in 2025, then retreated by 8.66% to $66.4 million in 2026.
  • The last three Operating Expenses figures came in at $66.4 million (Q1 2026), $72.7 million (Q4 2025), and $77.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.33 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -138.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 574,669.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.96 Bn 91.96 Bn - -67.40 Mn
10 Bicycle Therapeutics 278.04 Mn 278.04 Mn - 66.37 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 66.37 Mn
Dec 31, 2025 72.66 Mn
Sep 30, 2025 77.29 Mn
Jun 30, 2025 89.52 Mn
Mar 31, 2025 80.18 Mn
Dec 31, 2024 71.37 Mn
Sep 30, 2024 66.52 Mn
Jun 30, 2024 56.01 Mn
Mar 31, 2024 51.25 Mn
Dec 31, 2023 59.57 Mn
Sep 30, 2023 56.15 Mn
Jun 30, 2023 54.51 Mn
Mar 31, 2023 46.70 Mn
Dec 31, 2022 35.40 Mn
Sep 30, 2022 32.80 Mn
Jun 30, 2022 31.68 Mn
Mar 31, 2022 31.24 Mn
Dec 31, 2021 21.80 Mn
Sep 30, 2021 18.63 Mn
Jun 30, 2021 19.06 Mn