Autolus Therapeutics (AUTL) Operating Expenses (2017 - 2025)

Autolus Therapeutics (AUTL) posted quarterly Operating Expenses of $96.8 million for Q4 2025, up 27.49% year-on-year from $75.9 million in Q4 2024, and up 4.25% on a QoQ basis from $92.8 million in Q3 2025.

Autolus Therapeutics (AUTL) Operating Expenses (2017 - 2025) Analysis & Trends

Autolus Therapeutics (AUTL) has reported Operating Expenses for 9 consecutive years, with $96.8 million the latest figure, recorded in Q4 2025.

  • Quarterly Operating Expenses rose 27.49% year-over-year to $96.8 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $345.9 million (up 37.52% YoY) and the FY2025 annual result came in at $345.9 million, up 37.52% from the prior year.
  • Operating Expenses climbed to $96.8 million in Q4 2025 per AUTL's latest filing, from $92.8 million in the prior quarter.
  • Over the last five years, Operating Expenses for AUTL reached as high as $96.8 million in Q4 2025 and fell as low as $15.0 million in Q4 2022.
  • A 5-year average of $52.4 million and a median of $43.6 million in 2023 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2021 — Operating Expenses plunged 51.24% — and 2023, when it surged 256.09%.
  • Year by year, Operating Expenses stood at $23.3 million in 2021, then plunged by 35.73% to $15.0 million in 2022, then jumped by 256.09% to $53.3 million in 2023, then jumped by 42.47% to $75.9 million in 2024, then gained by 27.49% to $96.8 million in 2025.
  • According to Business Quant data, Operating Expenses over the past three periods registered $96.8 million, $92.8 million, and $82.1 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Autolus Therapeutics 404.53 Mn 103.82 Mn -1.04 Mn 96.76 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 96.76 Mn
Sep 30, 2025 92.82 Mn
Jun 30, 2025 82.14 Mn
Mar 31, 2025 74.22 Mn
Dec 31, 2024 75.89 Mn
Sep 30, 2024 67.88 Mn
Jun 30, 2024 58.93 Mn
Mar 31, 2024 48.85 Mn
Dec 31, 2023 53.27 Mn
Sep 30, 2023 42.93 Mn
Jun 30, 2023 44.35 Mn
Mar 31, 2023 36.67 Mn
Dec 31, 2022 14.96 Mn
Sep 30, 2022 39.72 Mn
Jun 30, 2022 39.06 Mn
Mar 31, 2022 36.35 Mn
Dec 31, 2021 23.28 Mn
Sep 30, 2021 40.59 Mn
Jun 30, 2021 39.37 Mn
Mar 31, 2021 39.47 Mn