Autolus Therapeutics (AUTL) Operating Expenses (2017 - 2025)
Autolus Therapeutics (AUTL) posted quarterly Operating Expenses of $96.8 million for Q4 2025, up 27.49% year-on-year from $75.9 million in Q4 2024, and up 4.25% on a QoQ basis from $92.8 million in Q3 2025.
Autolus Therapeutics (AUTL) Operating Expenses (2017 - 2025) Analysis & Trends
Autolus Therapeutics (AUTL) has reported Operating Expenses for 9 consecutive years, with $96.8 million the latest figure, recorded in Q4 2025.
- Quarterly Operating Expenses rose 27.49% year-over-year to $96.8 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $345.9 million (up 37.52% YoY) and the FY2025 annual result came in at $345.9 million, up 37.52% from the prior year.
- Operating Expenses climbed to $96.8 million in Q4 2025 per AUTL's latest filing, from $92.8 million in the prior quarter.
- Over the last five years, Operating Expenses for AUTL reached as high as $96.8 million in Q4 2025 and fell as low as $15.0 million in Q4 2022.
- A 5-year average of $52.4 million and a median of $43.6 million in 2023 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2021 — Operating Expenses plunged 51.24% — and 2023, when it surged 256.09%.
- Year by year, Operating Expenses stood at $23.3 million in 2021, then plunged by 35.73% to $15.0 million in 2022, then jumped by 256.09% to $53.3 million in 2023, then jumped by 42.47% to $75.9 million in 2024, then gained by 27.49% to $96.8 million in 2025.
- According to Business Quant data, Operating Expenses over the past three periods registered $96.8 million, $92.8 million, and $82.1 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 1.10 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.78 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 2.89 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 445.22 Mn |
| 10 | Autolus Therapeutics | 404.53 Mn | 103.82 Mn | -1.04 Mn | 96.76 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 96.76 Mn |
| Sep 30, 2025 | 92.82 Mn |
| Jun 30, 2025 | 82.14 Mn |
| Mar 31, 2025 | 74.22 Mn |
| Dec 31, 2024 | 75.89 Mn |
| Sep 30, 2024 | 67.88 Mn |
| Jun 30, 2024 | 58.93 Mn |
| Mar 31, 2024 | 48.85 Mn |
| Dec 31, 2023 | 53.27 Mn |
| Sep 30, 2023 | 42.93 Mn |
| Jun 30, 2023 | 44.35 Mn |
| Mar 31, 2023 | 36.67 Mn |
| Dec 31, 2022 | 14.96 Mn |
| Sep 30, 2022 | 39.72 Mn |
| Jun 30, 2022 | 39.06 Mn |
| Mar 31, 2022 | 36.35 Mn |
| Dec 31, 2021 | 23.28 Mn |
| Sep 30, 2021 | 40.59 Mn |
| Jun 30, 2021 | 39.37 Mn |
| Mar 31, 2021 | 39.47 Mn |