Autolus Therapeutics (AUTL) Operating Expenses (2017 - 2025)

Autolus Therapeutics posted quarterly Operating Expenses of $96.8 million for Q4 2025, up 27.49% year-on-year from $75.9 million in Q4 2024, and up 4.25% on a QoQ basis from $92.8 million in Q3 2025.

Autolus Therapeutics (AUTL) has 9 years of Operating Expenses data on file, last reported at $96.8 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses rose 27.49% year-over-year to $96.8 million; the trailing twelve-month figure through Dec 2025 stood at $345.9 million (up 37.52% YoY), and the FY2025 full-year result was $345.9 million, up 37.52% from the prior year.
  • Operating Expenses for Q4 2025 stood at $96.8 million, up from $92.8 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $320.2 million in Q4 2023 and bottomed at -$40.4 billion in Q3 2021.
  • The 5-year median for Operating Expenses is $31.9 million (2022), against an average of -$2.0 billion.
  • The widest annual swing landed in 2021, when Operating Expenses tumbled 94390.49%; it then surged 2040.47% in 2023.
  • A 5-year view of Operating Expenses shows it stood at $262.1 million in 2021, then slumped by 94.29% to $15.0 million in 2022, then soared by 2040.47% to $320.2 million in 2023, then slumped by 76.3% to $75.9 million in 2024, then increased by 27.49% to $96.8 million in 2025.
  • The last three Operating Expenses figures came in at $96.8 million (Q4 2025), $92.8 million (Q3 2025), and $82.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 2.97 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - 4.33 Mn
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 1.85 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 2.96 Bn
8 Evaxion A 65.12 Bn 65.10 Bn - -3.82 Mn
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 898.54 Mn
10 Autolus Therapeutics - - -1.04 Mn 96.76 Mn

Historic Data

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DateValue
Dec 31, 2025 96.76 Mn
Sep 30, 2025 92.82 Mn
Jun 30, 2025 82.14 Mn
Mar 31, 2025 74.22 Mn
Dec 31, 2024 75.89 Mn
Sep 30, 2024 67.88 Mn
Jun 30, 2024 58.93 Mn
Mar 31, 2024 48.85 Mn
Dec 31, 2023 320.21 Mn
Sep 30, 2023 -47.82 Mn
Jun 30, 2023 -47.89 Mn
Mar 31, 2023 -43.10 Mn
Dec 31, 2022 14.96 Mn
Sep 30, 2022 -43.49 Mn
Jun 30, 2022 -46.48 Mn
Mar 31, 2022 -41.78 Mn
Dec 31, 2021 262.13 Mn
Sep 30, 2021 -40.36 Bn
Jun 30, 2021 -37.72 Mn
Mar 31, 2021 -39.87 Mn
Dec 31, 2020 99.67 Mn
Sep 30, 2020 -42.71 Mn
Jun 30, 2020 -39.54 Mn
Mar 31, 2020 -38.56 Mn
Jun 30, 2019 -37.21 Mn
Mar 31, 2019 -30.16 Mn
Sep 30, 2018 -17.06 Mn
Jun 30, 2018 -16.52 Mn
Mar 31, 2018 -15.53 Mn
Dec 31, 2017 8.42 Mn