Aprea Therapeutics (APRE) Operating Expenses (2018 - 2026)
Aprea Therapeutics' Operating Expenses came in at $4.03 million for Q2 2026, up 15.0% from $3.51 million a year earlier and up 17.5% from the prior quarter.
Aprea Therapeutics (APRE) Operating Expenses (2018 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Aprea Therapeutics reported Operating Expenses of $13.23 million, down 15.4% year-over-year; for FY2025, it was $13.52 million, down 14.6% from FY2024.
- Operating Expenses has declined in each of the last three years, with a five-year compound annual growth rate of -23.9% (FY2020 to FY2025).
- Going back by year, Operating Expenses was $15.82 million in FY2024 (-1.5%), $16.06 million in FY2023 (-85.8%), $113.39 million in FY2022 (+202.8%) and $37.45 million in FY2021 (-29.1%).
- The Q2 2026 figure represents the highest quarterly Operating Expenses since Q1 2025.
- Year-over-year, Operating Expenses increased in three of the last eight quarters, with an average decline of 6.0%.
- The fastest year-over-year change in Operating Expenses over five years came in Q2 2022 (growth of 884.9%), and the weakest in Q2 2023 (a decline of 96.0%).
- Business Quant data shows APRE's Operating Expenses at $3.43 million (Q1 2026), $2.65 million (Q4 2025) and $3.12 million (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 10.12 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 10.56 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 12.80 Bn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | -6.09 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | -9.70 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 6.54 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | 18.20 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 6.68 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 2.09 Bn |
| 10 | Aprea Therapeutics | 41.18 Mn | 41.18 Mn | - | 4.03 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 4.03 Mn |
| Mar 31, 2026 | 3.43 Mn |
| Dec 31, 2025 | 2.65 Mn |
| Sep 30, 2025 | 3.12 Mn |
| Jun 30, 2025 | 3.51 Mn |
| Mar 31, 2025 | 4.25 Mn |
| Dec 31, 2024 | 3.43 Mn |
| Sep 30, 2024 | 4.45 Mn |
| Jun 30, 2024 | 4.41 Mn |
| Mar 31, 2024 | 3.53 Mn |
| Dec 31, 2023 | 3.69 Mn |
| Sep 30, 2023 | 3.84 Mn |
| Jun 30, 2023 | 3.90 Mn |
| Mar 31, 2023 | 4.62 Mn |
| Dec 31, 2022 | 2.65 Mn |
| Sep 30, 2022 | 4.20 Mn |
| Jun 30, 2022 | 98.47 Mn |
| Mar 31, 2022 | 8.07 Mn |
| Dec 31, 2021 | 7.83 Mn |
| Sep 30, 2021 | 9.43 Mn |
Aprea Therapeutics Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-expenses&ticker=APRE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-expenses", "ticker": "APRE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-expenses&ticker=APRE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();