Annexon (ANNX) Operating Expenses (2019 - 2026)
Annexon's (ANNX) quarterly Operating Expenses came in at $46.1 million in Q1 2026, down 19.78% year-on-year from $57.4 million in Q1 2025, and down 8.37% quarter-over-quarter from $50.3 million in Q4 2025.
Annexon (ANNX) Operating Expenses (2019 - 2026) Analysis & Trends
Annexon's Operating Expenses history runs 8 years deep, the most recent figure standing at $46.1 million for Q1 2026.
- On a quarterly basis, Operating Expenses fell 19.78% year-over-year to $46.1 million in Q1 2026; TTM through Mar 2026 was $205.1 million, a 12.11% increase from a year earlier, with the FY2025 full-year figure at $216.4 million, up 40.46% from the prior year.
- Operating Expenses declined to $46.1 million in Q1 2026 per ANNX's latest filing, from $50.3 million in the prior quarter.
- Across five years, Operating Expenses topped out at $57.4 million in Q1 2025 and bottomed at $28.6 million in Q1 2024.
- The 5-year median for Operating Expenses is $37.7 million (2023), against an average of $41.5 million.
- Across the five-year window, Operating Expenses slumped 30.72% in 2024 and surged 100.91% in 2025, its largest moves.
- Year by year, Operating Expenses stood at $36.7 million in 2022, then dropped by 18.22% to $30.0 million in 2023, then jumped by 74.88% to $52.5 million in 2024, then dropped by 4.23% to $50.3 million in 2025, then fell by 8.37% to $46.1 million in 2026.
- Per Business Quant, the three latest ANNX Operating Expenses figures stand at $46.1 million (Q1 2026), $50.3 million (Q4 2025), and $57.0 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | Annexon | 1.02 Bn | 798.41 Mn | - | 46.05 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 46.05 Mn |
| Dec 31, 2025 | 50.26 Mn |
| Sep 30, 2025 | 57.02 Mn |
| Jun 30, 2025 | 51.73 Mn |
| Mar 31, 2025 | 57.41 Mn |
| Dec 31, 2024 | 52.48 Mn |
| Sep 30, 2024 | 39.44 Mn |
| Jun 30, 2024 | 33.58 Mn |
| Mar 31, 2024 | 28.57 Mn |
| Dec 31, 2023 | 30.01 Mn |
| Sep 30, 2023 | 34.78 Mn |
| Jun 30, 2023 | 37.69 Mn |
| Mar 31, 2023 | 41.24 Mn |
| Dec 31, 2022 | 36.70 Mn |
| Sep 30, 2022 | 36.07 Mn |
| Jun 30, 2022 | 37.41 Mn |
| Mar 31, 2022 | 35.43 Mn |
| Dec 31, 2021 | 37.46 Mn |
| Sep 30, 2021 | 35.68 Mn |
| Jun 30, 2021 | 31.37 Mn |