Annexon (ANNX) Operating Expenses (2019 - 2026)

Annexon's (ANNX) quarterly Operating Expenses came in at $46.1 million in Q1 2026, down 19.78% year-on-year from $57.4 million in Q1 2025, and down 8.37% quarter-over-quarter from $50.3 million in Q4 2025.

Annexon (ANNX) Operating Expenses (2019 - 2026) Analysis & Trends

Annexon's Operating Expenses history runs 8 years deep, the most recent figure standing at $46.1 million for Q1 2026.

  • On a quarterly basis, Operating Expenses fell 19.78% year-over-year to $46.1 million in Q1 2026; TTM through Mar 2026 was $205.1 million, a 12.11% increase from a year earlier, with the FY2025 full-year figure at $216.4 million, up 40.46% from the prior year.
  • Operating Expenses declined to $46.1 million in Q1 2026 per ANNX's latest filing, from $50.3 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $57.4 million in Q1 2025 and bottomed at $28.6 million in Q1 2024.
  • The 5-year median for Operating Expenses is $37.7 million (2023), against an average of $41.5 million.
  • Across the five-year window, Operating Expenses slumped 30.72% in 2024 and surged 100.91% in 2025, its largest moves.
  • Year by year, Operating Expenses stood at $36.7 million in 2022, then dropped by 18.22% to $30.0 million in 2023, then jumped by 74.88% to $52.5 million in 2024, then dropped by 4.23% to $50.3 million in 2025, then fell by 8.37% to $46.1 million in 2026.
  • Per Business Quant, the three latest ANNX Operating Expenses figures stand at $46.1 million (Q1 2026), $50.3 million (Q4 2025), and $57.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Annexon 1.02 Bn 798.41 Mn - 46.05 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 46.05 Mn
Dec 31, 2025 50.26 Mn
Sep 30, 2025 57.02 Mn
Jun 30, 2025 51.73 Mn
Mar 31, 2025 57.41 Mn
Dec 31, 2024 52.48 Mn
Sep 30, 2024 39.44 Mn
Jun 30, 2024 33.58 Mn
Mar 31, 2024 28.57 Mn
Dec 31, 2023 30.01 Mn
Sep 30, 2023 34.78 Mn
Jun 30, 2023 37.69 Mn
Mar 31, 2023 41.24 Mn
Dec 31, 2022 36.70 Mn
Sep 30, 2022 36.07 Mn
Jun 30, 2022 37.41 Mn
Mar 31, 2022 35.43 Mn
Dec 31, 2021 37.46 Mn
Sep 30, 2021 35.68 Mn
Jun 30, 2021 31.37 Mn