Alnylam Pharmaceuticals (ALNY) Gross Margin (2018 - 2026)
Alnylam Pharmaceuticals (ALNY) reported Gross Margin of 76.90% for Q2 2026, down 4.75 percentage points from 81.64% a year earlier and down 5.32 percentage points from the prior quarter.
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Alnylam Pharmaceuticals (ALNY) Gross Margin (2018 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Alnylam Pharmaceuticals' Gross Margin came in at 79.79%, up 0.70 percentage points year-over-year; for FY2025, it was 81.77%, down 4.60 percentage points from FY2024.
- Gross Margin has a five-year change of -3.18 percentage points (FY2020 to FY2025).
- By year, Gross Margin came in at 86.37% in FY2024 (+1.04 pp), 85.33% in FY2023 (-1.16 pp), 86.49% in FY2022 (+0.11 pp) and 86.38% in FY2021 (+1.43 pp).
- Five-year quarterly Gross Margin spans a low of -133.94% in Q1 2025 and a high of 89.80% in Q2 2024.
- Year over year, Gross Margin gained in two of the last eight quarters, with an average year-over-year change of -4.11 percentage points.
- The high point for year-over-year Gross Margin in five years was Q1 2026 (a gain of 216.16 percentage points); the low point was Q1 2025 (a drop of 222.90 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at 82.22% (Q1 2026), 75.60% (Q4 2025) and 84.21% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 653.54 Bn | 572.07 Bn | 17.26 Bn | 68.19% |
| 2 | AbbVie | 467.01 Bn | 440.17 Bn | 12.70 Bn | 74.74% |
| 3 | Merck | 367.16 Bn | 321.59 Bn | 12.21 Bn | 73.54% |
| 4 | Novartis Ag | 277.56 Bn | 233.43 Bn | 11.24 Bn | 78.02% |
| 5 | Astrazeneca | 258.23 Bn | 231.79 Bn | 12.86 Bn | 83.60% |
| 6 | Amgen | 224.14 Bn | 179.54 Bn | 7.24 Bn | 72.04% |
| 7 | Gilead Sciences | 187.30 Bn | 161.42 Bn | 6.22 Bn | 79.76% |
| 8 | Pfizer | 163.47 Bn | 110.41 Bn | 10.94 Bn | 72.78% |
| 9 | Vertex Pharmaceuticals | 133.31 Bn | 105.31 Bn | 2.84 Bn | 85.33% |
| 10 | Alnylam Pharmaceuticals | 34.23 Bn | 22.28 Bn | 992.69 Mn | 76.90% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 76.90% |
| Mar 31, 2026 | 82.22% |
| Dec 31, 2025 | 75.60% |
| Sep 30, 2025 | 84.21% |
| Jun 30, 2025 | 81.64% |
| Dec 31, 2024 | 82.69% |
| Sep 30, 2024 | 83.63% |
| Jun 30, 2024 | 89.80% |
| Mar 31, 2024 | 88.95% |
| Dec 31, 2023 | 83.63% |
| Sep 30, 2023 | 89.41% |
| Jun 30, 2023 | 76.37% |
| Mar 31, 2023 | 87.02% |
| Dec 31, 2022 | 86.22% |
| Sep 30, 2022 | 86.19% |
| Jun 30, 2022 | 84.86% |
| Mar 31, 2022 | 89.00% |
| Dec 31, 2021 | 86.99% |
| Sep 30, 2021 | 85.03% |
| Jun 30, 2021 | 86.28% |
API Access
Alnylam Pharmaceuticals Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "ALNY", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY");
const data = await res.json();