Alnylam Pharmaceuticals, Inc. (ALNY) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

136,298,000Shares Outstanding

129,650,152Shares held by institutions

$41,490,641,643Value of institutional holdings

95.12%Institutional ownership %

-4.02%Shares Changed QoQ

825No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) has 823 institutional investors with active 13F positions as of December 2025.

These investors held 94.8% of outstanding shares in December 2025, down from 102.0% in September 2025.
They decreased total shares held in Alnylam Pharmaceuticals by -4.23% from last quarter, and the number of investors in ALNY increased 40.92% annually.
Of these 823 funds, 442 grew their exposure to Alnylam Pharmaceuticals, 283 cut back, and 98 maintained positions.
Institutional investors collectively held 129.18Mn shares in Alnylam Pharmaceuticals as of December 2025, down by 5.7Mn shares quarter on quarter, and down 2.5Mn shares year over year.
As of December 31, 2025, Hilltop National Bank held the largest stake in Alnylam Pharmaceuticals with 131 shares, accounting for 0.0% of total shares outstanding.
The most significant purchases of ALNY for the quarter ending December 2025 came from Hilltop National Bank (51), Investors Research Corp (2).
According to Business Quant data, leading holders of ALNY for December 2025 are Hilltop National Bank (131), Ares Financial Consulting, LLC (20), Investors Research Corp (2).

825 Institutional Holders

129,650,152 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Capital World Investors	31 Dec, 2025	16,301,772	-132,481	-0.81%	$6,482,389,029.00
FMR LLC	31 Dec, 2025	15,902,149	-865,476	-5.16%	$6,323,489,463.00
VANGUARD GROUP INC	31 Dec, 2025	13,553,932	-11,520	-0.08%	$5,389,721,059.00
BlackRock, Inc.	31 Dec, 2025	10,400,874	497,273	5.02%	$4,135,907,609.00
Capital Research Global Investors	31 Dec, 2025	6,779,708	-443,132	-6.14%	$2,695,945,984.00
Jpmorgan Chase & Co	31 Dec, 2025	4,719,999	-4,367,541	-48.06%	$1,876,908,009.00
State Street Corp	31 Dec, 2025	3,228,956	147,481	4.79%	$1,283,994,353.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	2,904,987	731,003	33.63%	$1,155,169.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,650,722	151,480	6.06%	$1,056,883,596.00
BAILLIE GIFFORD & CO	31 Dec, 2025	2,600,979	-188,377	-6.75%	$1,034,279,300.00
NORGES BANK	31 Dec, 2025	2,252,775	2,252,775	0.00%	$895,815,979.00
Invesco Ltd.	31 Dec, 2025	2,165,840	683,998	46.16%	$861,246,230.00
DODGE & COX	31 Dec, 2025	1,964,415	-356,815	-15.37%	$781,149,625.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	1,628,931	-197,390	-10.81%	$647,744,413.00
Orbis Allan Gray Ltd	31 Dec, 2025	1,618,219	-332,743	-17.06%	$643,484,786.00
AMERICAN CENTURY COMPANIES INC	31 Dec, 2025	1,485,161	-156,280	-9.52%	$590,576,553.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	1,132,560	240,060	26.90%	$450,362,484.00
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	31 Dec, 2025	1,127,162	-228,447	-16.85%	$448,215,969.00
Morgan Stanley	31 Dec, 2025	970,157	244,096	33.62%	$385,784,277.00
Legal & General Group Plc	31 Dec, 2025	961,496	73,716	8.30%	$382,338,888.00

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