Agios Pharmaceuticals (AGIO) Return on Capital Employed (2013 - 2026)
Agios Pharmaceuticals (AGIO) reported Return on Capital Employed of 40.22% for Q1 2026, down 1194.0% on a YoY basis from 3.68% in Q1 2025, and down 7.28% quarter-over-quarter from 37.49% in Q4 2025.
Agios Pharmaceuticals (AGIO) Return on Capital Employed (2013 - 2026) Analysis & Trends
Agios Pharmaceuticals has reported Return on Capital Employed for 14 years, with the latest figure at 40.22% in Q1 2026.
- For the quarter ending Q1 2026, Return on Capital Employed fell 1194.0% year-over-year to 40.22%; the trailing twelve-month figure through Mar 2026 stood at 40.22% (down 1194.0% YoY), and the FY2025 full-year result was 33.77%, up 115.0% from the prior year.
- Return on Capital Employed for Q1 2026 stood at 40.22%, down from 37.49% in the prior quarter.
- The five-year high for Return on Capital Employed was 25.86% in Q4 2024, with the low at 54.1% in Q2 2024.
- Historically, Return on Capital Employed has averaged 36.1% across 5 years, with a median of 34.99% in 2024.
- Annual changes were most pronounced in 2024 — Return on Capital Employed sank 1886 bps — and 2025, when it jumped 2211 bps.
- Agios Pharmaceuticals' Return on Capital Employed stood at 33.92% in 2022, then declined by 28 bps to 43.29% in 2023, then jumped by 40 bps to 25.86% in 2024, then sank by 45 bps to 37.49% in 2025, then retreated by 7 bps to 40.22% in 2026.
- The last three Return on Capital Employed figures came in at 40.22% (Q1 2026), 37.49% (Q4 2025), and 35.13% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 450.31% |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 51.73% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -107.40% |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -50.43% |
| 10 | Agios Pharmaceuticals | 2.01 Bn | 2.01 Bn | 19.43 Mn | -40.22% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -40.22% |
| Dec 31, 2025 | -37.49% |
| Sep 30, 2025 | -35.13% |
| Jun 30, 2025 | -31.98% |
| Mar 31, 2025 | -28.28% |
| Dec 31, 2024 | -25.86% |
| Sep 30, 2024 | -34.99% |
| Jun 30, 2024 | -54.10% |
| Mar 31, 2024 | -46.68% |
| Dec 31, 2023 | -43.29% |
| Sep 30, 2023 | -38.91% |
| Jun 30, 2023 | -35.23% |
| Mar 31, 2023 | -32.92% |
| Dec 31, 2022 | -33.92% |
| Sep 30, 2022 | -33.94% |
| Jun 30, 2022 | -31.69% |
| Mar 31, 2022 | -28.96% |
| Dec 31, 2021 | -26.47% |
| Sep 30, 2021 | -22.18% |
| Jun 30, 2021 | -16.75% |