Agios Pharmaceuticals, Inc. (AGIO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

58,349,497Shares Outstanding

61,989,146Shares held by institutions

$2,146,374,180Value of institutional holdings

106.24%Institutional ownership %

14.27%Shares Changed QoQ

232No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) has 232 institutional investors with active 13F positions as of December 2025.

These investors collectively held 104.4% of Agios Pharmaceuticals's outstanding shares in December 2025, down from 121.6% in September 2025.
They increased total shares held in Agios Pharmaceuticals by 13.09% from the prior quarter, while the number of investors in AGIO increased 4.98% year over year.
Of these 232 holders, 142 added to their stakes in Agios Pharmaceuticals, 66 trimmed positions, and 24 made no changes.
The aggregate institutional position in Agios Pharmaceuticals amounted to 60.9Mn shares as of December 2025, up by 7.05Mn shares quarter on quarter, and down 1.8Mn shares year over year.
VANGUARD GROUP INC is the top holder of Agios Pharmaceuticals as of December 31, 2025, with 5.59Mn shares representing 9.59% of outstanding stock.
Leading buyers of Agios Pharmaceuticals shares for the quarter ending December 2025 were ARMISTICE CAPITAL, LLC (2.27Mn), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (1.7Mn), D. E. Shaw & Co., Inc. (1.47Mn), MPM BioImpact LLC (1.3Mn), Goldman Sachs Group Inc (1.26Mn).
The biggest sellers of Agios Pharmaceuticals for the quarter ending December 2025 included FARALLON CAPITAL MANAGEMENT LLC (6.4Mn), WELLINGTON MANAGEMENT GROUP LLP (1.87Mn), Bank Of America Corp /De/ (1.72Mn), DEUTSCHE BANK AG\ (803.86K), BOOTHBAY FUND MANAGEMENT, LLC (458.05K).
Per Business Quant data, the top 10 holders of Agios Pharmaceuticals for the quarter ending December 2025 are VANGUARD GROUP INC (5.59Mn), BlackRock, Inc. (5.24Mn), FARALLON CAPITAL MANAGEMENT LLC (5.16Mn), State Street Corp (3.11Mn), ARMISTICE CAPITAL, LLC (3.04Mn), Erste Asset Management GmbH (2.8Mn), Goldman Sachs Group Inc (2.07Mn), D. E. Shaw & Co., Inc. (1.84Mn), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (1.7Mn), GEODE CAPITAL MANAGEMENT, LLC (1.41Mn).

232 Institutional Holders

61,989,146 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	5,594,353	-10,523	-0.19%	$152,278,288.00
BlackRock, Inc.	31 Dec, 2025	5,235,429	689,691	15.17%	$142,508,377.00
FARALLON CAPITAL MANAGEMENT LLC	31 Dec, 2025	5,159,505	-6,402,627	-55.38%	$140,441,726.00
State Street Corp	31 Dec, 2025	3,108,145	845,433	37.36%	$84,603,707.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	3,036,000	2,272,000	297.38%	$82,639,920.00
Erste Asset Management GmbH	31 Dec, 2025	2,804,900	40,000	1.45%	$76,343,084.00
Goldman Sachs Group Inc	31 Dec, 2025	2,067,948	1,263,182	156.96%	$56,289,544.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	1,837,186	1,469,437	399.58%	$50,008,203.00
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	31 Dec, 2025	1,701,409	1,701,409	0.00%	$46,312,000.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,413,538	-2,777	-0.20%	$38,483,546.00
BNP Paribas Asset Management Holding S.A.	31 Dec, 2025	1,360,730	373,391	37.82%	$37,039.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,348,968	856,986	174.19%	$36,718,909.00
MPM BioImpact LLC	31 Dec, 2025	1,303,373	1,303,373	0.00%	$35,477,813.00
Frazier Life Sciences Management, L.P.	31 Dec, 2025	1,279,754	0	0.00%	$34,834,904.00
GW&K Investment Management, LLC	31 Dec, 2025	1,207,301	354,359	41.55%	$32,863.00
TCG Crossover Management, LLC	31 Dec, 2025	1,181,841	-248,200	-17.36%	$32,169,712.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	1,142,432	1,142,432	0.00%	$31,096,999.00
JANE STREET GROUP, LLC	31 Dec, 2025	1,121,050	725,930	183.72%	$30,514,981.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	1,004,341	-16,860	-1.65%	$27,338,360.00
Morgan Stanley	31 Dec, 2025	894,037	477,039	114.40%	$24,335,710.00

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