Agios Pharmaceuticals, Inc. (AGIO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

57,974,860Shares Outstanding

2,047,055Shares held by institutions

$56,949,070Value of institutional holdings

105.03%Institutional ownership %

29.93%Shares Changed QoQ

228No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) is held by 228 institutional firms.

Agios Pharmaceuticals saw its institutional ownership percentage fell to 105.0% in December 2025 from 112.0% in September 2025.
Quarterly data indicates a 29.93% shift in institutional share volume, and the annual owner count reflects an increase of 2.70%.
Of these 228 institutional investors, 140 increased their holdings in Agios Pharmaceuticals, while 64 of them reduced positions, and 24 investors maintained their exposure.
Collectively, institutional investors increased their stake in Agios Pharmaceuticals to 60.89Mn shares as of December 2025, a change that is up by 14.03Mn shares quarter on quarter and up 948.97K shares year over year.
VANGUARD GROUP INC continues to be the largest institutional holder of Agios Pharmaceuticals as of December 31, 2025, with a position of 5.59Mn shares, representing 9.65% of the company's outstanding stock.
Among the most significant buyers of Agios Pharmaceuticals during December 2025 were ARMISTICE CAPITAL, LLC (2.27Mn), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (1.70Mn), D. E. Shaw & Co., Inc. (1.47Mn), MPM BioImpact LLC (1.30Mn), SUSQUEHANNA INTERNATIONAL GROUP, LLP (1.14Mn).
Leading sellers of Agios Pharmaceuticals stock in December 2025 included WELLINGTON MANAGEMENT GROUP LLP (1.87Mn), DEUTSCHE BANK AG\ (803.86K), FARALLON CAPITAL MANAGEMENT LLC (621.56K), BANK OF AMERICA CORP /DE/ (590.66K), BOOTHBAY FUND MANAGEMENT, LLC (458.05K).
The top 10 institutional holders of Agios Pharmaceuticals for the quarter ending December 2025 included VANGUARD GROUP INC (5.59Mn), BlackRock, Inc. (5.24Mn), FARALLON CAPITAL MANAGEMENT LLC (5.16Mn), STATE STREET CORP (3.11Mn), ARMISTICE CAPITAL, LLC (3.04Mn), Erste Asset Management GmbH (2.80Mn), D. E. Shaw & Co., Inc. (1.84Mn), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (1.70Mn), JANE STREET GROUP, LLC (1.45Mn), GEODE CAPITAL MANAGEMENT, LLC (1.41Mn).

228 Institutional Holders

2,047,055 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	5,594,353	-10,523	-0.19%	$152,278,288.00
BlackRock, Inc.	31 Dec, 2025	5,235,429	689,691	15.17%	$142,508,377.00
FARALLON CAPITAL MANAGEMENT LLC	31 Dec, 2025	5,159,505	-621,561	-10.75%	$140,441,726.00
STATE STREET CORP	31 Dec, 2025	3,108,145	845,433	37.36%	$84,603,707.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	3,036,000	2,272,000	297.38%	$82,639,920.00
Erste Asset Management GmbH	31 Dec, 2025	2,804,900	40,000	1.45%	$76,343,084.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	1,837,186	1,469,437	399.58%	$50,008,203.00
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	31 Dec, 2025	1,701,409	1,701,409	0.00%	$46,312,000.00
JANE STREET GROUP, LLC	31 Dec, 2025	1,449,150	986,030	212.91%	$39,445,863.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,413,538	-2,777	-0.20%	$38,483,546.00
BNP Paribas Asset Management Holding S.A.	31 Dec, 2025	1,360,730	373,391	37.82%	$37,039.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,348,968	856,986	174.19%	$36,718,909.00
MPM BioImpact LLC	31 Dec, 2025	1,303,373	1,303,373	0.00%	$35,477,813.00
Frazier Life Sciences Management, L.P.	31 Dec, 2025	1,279,754	0	0.00%	$34,834,904.00
GW&K Investment Management, LLC	31 Dec, 2025	1,207,301	354,359	41.55%	$32,863.00
TCG Crossover Management, LLC	31 Dec, 2025	1,181,841	-248,200	-17.36%	$32,169,712.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	1,142,432	1,142,432	0.00%	$31,096,999.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	1,033,974	229,208	28.48%	$28,144,772.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	1,004,341	-16,860	-1.65%	$27,338,360.00
MORGAN STANLEY	31 Dec, 2025	894,037	477,039	114.40%	$24,335,710.00

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