CAI vs NEO vs GRAL Stock Comparison

Caris Life Sciences, Neogenomics and Grail Prices as of Nov 2, 2026 Peers: Industry group
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NEO Neogenomics Inc
$16.49 -10.7% 1M +68.8% 1Y
Market cap
$2.13B
P/E
–
Revenue (TTM)
$787.75M
Div. yield
–
Diagnostic Labs Healthcare
3 wins
GRAL GRAIL, Inc.
$133.76 -6.6% 1M +45.5% 1Y
Market cap
$5.97B
P/E
–
Revenue (TTM)
$157.21M
Div. yield
–
Diagnostic Labs Healthcare

Head to Head

7 decided of 12

Caris Life Sciences leads on 4 of the 12 questions below (Caris Life Sciences 4, Neogenomics 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCAINEOGRALLeader
Larger companyMarket capitalisation $9.07B $2.13B $5.97B CAI
Cheaper on earningsLower P/E, profitable companies only 86.4x -65.7x -14.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 291.8x 82.4x — NEO
Faster revenue growthRevenue growth, trailing twelve months +85.4% +11.1% +17.1% CAI
More profitableNet margin, trailing twelve months 10.6% -4.1% -249.1% CAI
Better return on capitalReturn on invested capital 15.6% — — –
Less leveragedLower net debt / EBITDA -2.2x — — –
Higher dividend yieldTrailing dividend yield 0.00% — — –
Better 1-year returnPrice return, last 12 months +6.7% +68.8% +45.5% NEO
Better 5-year returnAnnualised price return, 5 years — -18.7%/yr — –
Less volatileAnnualised volatility, 1 year 70.0% 53.9% 112.1% NEO
Higher overall scoreMean of the five percentile scores vs peers 69/100 42/100 43/100 CAI

Percentile Scorecard

CAINEOGRAL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCAINEOGRAL
Valuation 23 #73 of 94 31 #65 of 94 8 #87 of 94
Growth 99 #2 of 87 58 #37 of 87 59 #36 of 87
Profitability 87 #12 of 86 33 #58 of 86 6 #81 of 86
Financial Health 83 #18 of 99 69 #31 of 99 99 #2 of 99
Shareholder Returns 55 #26 of 56 18 #46 of 56 –
Overall 69 42 43
  • CAI ranked among 102 companies in Healthcare Providers
  • NEO ranked among 102 companies in Healthcare Providers
  • GRAL ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCAINEOGRALSPY
1 month +13.4%-10.7%-6.6% -2.3%
3 months +96.7%+4.1%+90.4% -0.7%
6 months +71.7%+83.2%+140.3% +4.8%
Year to date +19.0%+40.2%+56.3% +10.3%
1 year +6.7%+68.8%+45.5% +10.3%
3 years —+8.0%— +73.0%
3 years, per year —+2.6%— +20.1%
5 years —-64.6%— +61.9%
5 years, per year —-18.7%— +10.1%
10 years —+110.3%— +258.6%
10 years, per year —+7.7%— +13.6%

Risk

MeasureCAINEOGRALSPY
Volatility, 1Y 70.0%53.9%112.1% 12.8%
Downside volatility, 1Y 70.3%53.0%127.3% 12.8%
Beta vs S&P 500, 1Y 1.521.072.84 1.00
Return / volatility, 1Y 0.101.280.41 0.80
Max drawdown, 5Y -63.0%-89.6%-62.9% -25.4%
From 52-week high -11.2%-17.2%-15.8% -3.5%
52-week high $36.14$19.91$158.92 $779.14
52-week low $14.55$7.19$43.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCAINEOGRAL
P/E now vs peer median 86.4xmedian 25.3x -65.7xmedian 25.3x -14.7xmedian 25.3x
P/S now vs peer median 9.2xmedian 1.5x 2.7xmedian 1.5x 38.0xmedian 1.5x
EV/EBITDA now vs peer median 48.2xmedian 14.6x 119.3xmedian 14.6x -12.6xmedian 14.6x
P/FCF now vs peer median 73.2xmedian 21.6x -74.5xmedian 21.6x -20.2xmedian 21.6x
P/B now vs peer median 15.3xmedian 3.1x 2.7xmedian 3.1x 2.3xmedian 3.1x
PEG now vs peer median —median 0.83 -2.11median 0.83 —median 0.83

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCAINEOGRAL
Revenue $989.61M $787.75M $157.21M
Gross profit $689.36M $352.67M $75.51M
Operating income $153.26M -$49.37M -$559.25M
Net income $105.14M -$32.30M -$391.59M
Free cash flow $123.96M -$28.58M -$296.16M
R&D $117.14M $39.33M $190.72M
EPS (diluted) $0.37 $-0.25 $-9.08
Cash & equivalents $690.92M $139.28M $55.65M
Total debt $393.15M – –
Shares (diluted) 282.89M 128.59M 43.11M
Enterprise value $5.90B $1.54B $2.85B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCAINEOGRAL
P/E 86.4x -65.7x -14.7x
P/FCF 73.2x -74.5x -20.2x
P/Operating cash flow 53.8x 497.4x -20.3x
P/S 9.2x 2.7x 38.0x
P/B 15.3x 2.7x 2.3x
P/Tangible book 15.3x 4.0x 7.8x
EV/EBITDA 48.2x 119.3x -12.6x
EV/EBIT 56.6x -40.3x -9.1x
EV/Revenue 8.8x 2.5x 32.5x
EV/FCF 70.0x -69.6x -17.3x
EV/Operating cash flow 51.4x 464.9x -17.3x
PEG (3Y EPS CAGR) – -2.11 –

Growth

14 metrics
MetricCAINEOGRAL
Revenue growth (1Y) 85.4% 11.1% 17.1%
Revenue CAGR (3Y) – 11.1% –
Gross profit growth (1Y) 141.2% 14.4% 30.2%
Gross profit CAGR (3Y) – 14.7% –
Operating income growth (1Y) 188.2% 59.2% 11.6%
Operating income CAGR (3Y) – 24.7% –
Net income growth (1Y) 137.7% 71.5% 11.6%
Net income CAGR (3Y) – 30.5% –
EPS growth (1Y) 103.0% 71.6% 26.6%
EPS CAGR (3Y) – 31.1% –
Operating cash flow growth (1Y) 227.3% -68.7% 20.3%
Operating cash flow CAGR (3Y) – 29.7% –
Free cash flow growth (1Y) 188.2% -67.7% 20.3%
Free cash flow CAGR (3Y) – 16.8% –

Profitability

14 metrics
MetricCAINEOGRAL
Gross margin 69.7% 44.8% 48.0%
EBITDA margin 18.2% 2.1% -257.6%
Operating margin 15.5% -6.3% -355.7%
Pretax margin 10.6% -4.6% -336.8%
Net margin 10.6% -4.1% -249.1%
FCF margin 12.5% -3.6% -188.4%
Operating cash flow margin 17.0% 0.5% -187.5%
Return on equity 17.7% -4.1% -15.5%
Return on assets 8.8% -2.4% -13.9%
Return on invested capital 15.6% – –
Return on capital employed 15.3% -4.0% -20.4%
Asset turnover 0.8x 0.6x 0.1x
Cash conversion (OCF / net income) 1.6x -0.1x 0.8x
Stock comp / revenue 6.6% 4.4% 40.9%

Financial Health

11 metrics
MetricCAINEOGRAL
Debt / assets 32.0% – –
Debt / equity 0.7x – –
Net debt / EBITDA -2.2x – –
Debt / FCF 3.2x – –
Liabilities / assets 51.9% 41.9% 10.6%
Equity / assets 48.1% 58.1% 89.4%
Interest coverage 3.3x -15.2x –
Current ratio 5.5x 3.5x 10.9x
Quick ratio 4.8x 3.0x 10.6x
Cash ratio 4.1x 1.2x 10.3x
Altman Z-score 7.69 2.46 6.54

Shareholder Returns

7 metrics
MetricCAINEOGRAL
Dividend yield – – –
Net buyback yield 0.1% -0.7% –
Shareholder yield 0.1% -0.7% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCAINEOGRAL
Forward P/E 291.8xFY2026 82.4xFY2026 –
EPS, next fiscal year $0.11FY2026 $0.20FY2026 $-9.05FY2026
EPS growth, next FY – +66.7%FY2026 –
EPS growth, the year after +236.4% +80.0% –
Revenue, next fiscal year $1.06BFY2026 $778.61MFY2026 $169.78MFY2026
Revenue growth, next FY +30.1%FY2026 +7.1%FY2026 +15.4%FY2026
Revenue growth, the year after +21.6% +6.5% +38.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCAINEOGRAL
Held by institutions 52.0% 100.0% 85.4%
Institutions holding 246 266 374
Change in shares held, QoQ -6.3% +8.1% +8.4%
Institutions buying 175 156 183
Institutions selling 47 62 101
Buyers to sellers 3.72 2.52 1.81

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CAINEOGRAL
CAI 1.00 0.44 0.35
NEO 0.44 1.00 0.32
GRAL 0.35 0.32 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CAI, NEO and GRAL?

Caris Life Sciences (CAI) is the largest by market capitalisation: Caris Life Sciences (CAI) $9.07B, Neogenomics (NEO) $2.13B, Grail (GRAL) $5.97B.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Caris Life Sciences (CAI) +85.4%, Neogenomics (NEO) +11.1%, Grail (GRAL) +17.1%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (Caris Life Sciences (CAI) 10.6%, Neogenomics (NEO) -4.1%, Grail (GRAL) -249.1%).

Which stock has performed better?

Over the past year Neogenomics (NEO) returned the most: Caris Life Sciences (CAI) +6.7%, Neogenomics (NEO) +68.8%, Grail (GRAL) +45.5%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Neogenomics (NEO) has been the steadiest (Caris Life Sciences (CAI) 70.0%, Neogenomics (NEO) 53.9%, Grail (GRAL) 112.1%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CAI, NEO and GRAL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Caris Life Sciences (CAI) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.