CAI vs NTRA Stock Comparison

Caris Life Sciences and Natera Prices as of Oct 23, 2026 Peers: Industry group
NTRA Natera, Inc.
$403.95 +3.4% 1M +107.2% 1Y
Market cap
$58.02B
P/E
–
Revenue (TTM)
$2.71B
Div. yield
–
Diagnostic Labs Healthcare
3 wins

Head to Head

8 decided of 12

Caris Life Sciences leads on 5 of the 12 questions below (Caris Life Sciences 5, Natera 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCAINTRALeader
Larger companyMarket capitalisation $9.19B $58.02B NTRA
Cheaper on earningsLower P/E, profitable companies only 87.4x -301.5x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 290.9x — –
Faster revenue growthRevenue growth, trailing twelve months +85.4% +37.8% CAI
More profitableNet margin, trailing twelve months 10.6% -7.1% CAI
Better return on capitalReturn on invested capital 15.6% -11.7% CAI
Less leveragedLower net debt / EBITDA -2.2x 4.5x CAI
Higher dividend yieldTrailing dividend yield 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +1.1% +107.2% NTRA
Better 5-year returnAnnualised price return, 5 years — +28.6%/yr –
Less volatileAnnualised volatility, 1 year 69.5% 47.9% NTRA
Higher overall scoreMean of the five percentile scores vs peers 69/100 50/100 CAI

Percentile Scorecard

CAINTRA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCAINTRA
Valuation 23 #72 of 93 16 #78 of 93
Growth 99 #2 of 88 71 #26 of 88
Profitability 87 #12 of 87 33 #59 of 87
Financial Health 82 #19 of 100 86 #15 of 100
Shareholder Returns 53 #27 of 56 44 #32 of 56
Overall 69 50
  • CAI ranked among 103 companies in Healthcare Providers
  • NTRA ranked among 103 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCAINTRASPY
1 month +1.1%+3.4% -1.0%
3 months +106.2%+54.2% +2.9%
6 months +58.4%+98.3% +6.4%
Year to date +18.6%+76.3% +11.4%
1 year +1.1%+107.2% +13.1%
3 years —+890.3% +79.4%
3 years, per year —+114.9% +21.5%
5 years —+251.5% +67.7%
5 years, per year —+28.6% +10.9%
10 years —+3,943.5% +255.2%
10 years, per year —+44.8% +13.5%

Risk

MeasureCAINTRASPY
Volatility, 1Y 69.5%47.9% 12.7%
Downside volatility, 1Y 68.9%44.1% 12.7%
Beta vs S&P 500, 1Y 1.341.21 1.00
Return / volatility, 1Y 0.022.24 1.03
Max drawdown, 5Y -63.0%-76.4% -25.4%
From 52-week high -1.1%-5.1% -2.5%
52-week high $32.35$425.64 $779.14
52-week low $14.55$182.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCAINTRA
P/E now vs peer median 86.1xmedian 25.3x -300.8xmedian 25.3x
P/S now vs peer median 9.1xmedian 1.6x 21.4xmedian 1.6x
EV/EBITDA now vs peer median 48.0xmedian 14.6x -254.2xmedian 14.6x
P/FCF now vs peer median 73.0xmedian 22.7x 689.0xmedian 22.7x
P/B now vs peer median 15.3xmedian 3.3x 31.8xmedian 3.3x
PEG now vs peer median —median 0.66 -9.07median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCAINTRA
Revenue $989.61M $2.71B
Gross profit $689.36M $1.71B
Operating income $153.26M -$289.67M
Net income $105.14M -$192.36M
Free cash flow $123.96M $84.20M
R&D $117.14M $787.38M
EPS (diluted) $0.37 $-1.34
Cash & equivalents $690.92M $1.10B
Total debt $393.15M $321.26M
Shares (diluted) 282.89M 143.28M
Enterprise value $6.01B $53.70B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCAINTRA
P/E 86.1x -300.8x
P/FCF 73.0x 689.0x
P/Operating cash flow 53.6x 254.2x
P/S 9.1x 21.4x
P/B 15.3x 31.8x
P/Tangible book 15.3x 39.7x
EV/EBITDA 48.0x -254.2x
EV/EBIT 56.4x -196.7x
EV/Revenue 8.7x 21.1x
EV/FCF 69.7x 676.9x
EV/Operating cash flow 51.3x 249.7x
PEG (3Y EPS CAGR) – -9.07

Growth

14 metrics
MetricCAINTRA
Revenue growth (1Y) 85.4% 37.8%
Revenue CAGR (3Y) – 42.7%
Gross profit growth (1Y) 141.2% 43.6%
Gross profit CAGR (3Y) – 68.1%
Operating income growth (1Y) 188.2% 1.3%
Operating income CAGR (3Y) – 17.3%
Net income growth (1Y) 137.7% 24.0%
Net income CAGR (3Y) – 27.8%
EPS growth (1Y) 103.0% 27.7%
EPS CAGR (3Y) – 33.2%
Operating cash flow growth (1Y) 227.3% 22.2%
Operating cash flow CAGR (3Y) – 38.6%
Free cash flow growth (1Y) 188.2% -26.8%
Free cash flow CAGR (3Y) – 30.4%

Profitability

14 metrics
MetricCAINTRA
Gross margin 69.7% 63.2%
EBITDA margin 18.2% -8.3%
Operating margin 15.5% -10.7%
Pretax margin 10.6% -9.3%
Net margin 10.6% -7.1%
FCF margin 12.5% 3.1%
Operating cash flow margin 17.0% 8.4%
Return on equity 17.7% -10.7%
Return on assets 8.8% -7.3%
Return on invested capital 15.6% -11.7%
Return on capital employed 15.3% -13.9%
Asset turnover 0.8x 1.0x
Cash conversion (OCF / net income) 1.6x -1.2x
Stock comp / revenue 6.6% 14.1%

Financial Health

11 metrics
MetricCAINTRA
Debt / assets 32.0% 3.0%
Debt / equity 0.7x 0.0x
Net debt / EBITDA -2.2x 4.5x
Debt / FCF 3.2x 1.0x
Liabilities / assets 51.9% 31.5%
Equity / assets 48.1% 68.5%
Interest coverage 3.3x -75.9x
Current ratio 5.5x 3.0x
Quick ratio 4.8x 2.8x
Cash ratio 4.1x 2.0x
Altman Z-score 7.66 41.25

Shareholder Returns

7 metrics
MetricCAINTRA
Dividend yield – –
Net buyback yield 0.1% -0.1%
Shareholder yield 0.1% -0.1%
Payout ratio (earnings) – –
Payout ratio (FCF) – –
Dividend growth (1Y) – –
Dividend CAGR (3Y) – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCAINTRA
Forward P/E 290.9xFY2026 –
EPS, next fiscal year $0.11FY2026 $-1.47FY2026
EPS growth, the year after +236.4% –
Revenue, next fiscal year $1.06BFY2026 $3.07BFY2026
Revenue growth, next FY +30.1%FY2026 +32.8%FY2026
Revenue growth, the year after +21.6% +6.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCAINTRA
Held by institutions 52.0% 95.5%
Institutions holding 245 847
Change in shares held, QoQ -6.3% +2.7%
Institutions buying 175 513
Institutions selling 47 240
Buyers to sellers 3.72 2.14

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CAINTRA
CAI 1.00 0.55
NTRA 0.55 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CAI and NTRA?

Natera (NTRA) is the largest by market capitalisation: Caris Life Sciences (CAI) $9.19B, Natera (NTRA) $58.02B.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Caris Life Sciences (CAI) +85.4%, Natera (NTRA) +37.8%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (Caris Life Sciences (CAI) 10.6%, Natera (NTRA) -7.1%). On return on invested capital, Caris Life Sciences (CAI) leads (Caris Life Sciences (CAI) 15.6%, Natera (NTRA) -11.7%).

Which stock has performed better?

Over the past year Natera (NTRA) returned the most: Caris Life Sciences (CAI) +1.1%, Natera (NTRA) +107.2%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Natera (NTRA) has been the steadiest (Caris Life Sciences (CAI) 69.5%, Natera (NTRA) 47.9%). Volatility measures how widely the price swings, not the risk of the business.

Do CAI and NTRA move together?

Their daily returns over the past year have a correlation of 0.55, a moderate positive relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, CAI and NTRA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Caris Life Sciences (CAI) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.