ALNY vs ARGX vs NXTS Stock Comparison

Alnylam Pharmaceuticals, Argenx Se and Nexentis Technologies Prices as of Oct 28, 2026 Peers: Industry group
ARGX Argenx Se
$891.76 -8.3% 1M +6.6% 1Y
Market cap
$55.00B
P/E
29.3x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
8 wins

Head to Head

9 decided of 12

Argenx Se leads on 8 of the 12 questions below (Argenx Se 8, Alnylam Pharmaceuticals 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALNYARGXNXTSLeader
Larger companyMarket capitalisation $23.30B $55.00B $514.98K ARGX
Cheaper on earningsLower P/E, profitable companies only 31.8x 29.3x 0.0x ARGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS 34.4x 29.1x — ARGX
Faster revenue growthRevenue growth, trailing twelve months +90.1% +61.5% — ALNY
More profitableNet margin, trailing twelve months 15.3% 32.3% — ARGX
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — 1.6x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -51.2% +6.6% -97.4% ARGX
Better 5-year returnAnnualised price return, 5 years +7.8%/yr +24.2%/yr -85.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 51.3% 36.9% 169.0% ARGX
Higher overall scoreMean of the five percentile scores vs peers 77/100 92/100 32/100 ARGX

Percentile Scorecard

ALNYARGXNXTS

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALNYARGXNXTS
Valuation 81 #119 of 625 84 #101 of 625 –
Growth 98 #13 of 602 94 #35 of 602 14 #521 of 602
Profitability 93 #41 of 549 98 #11 of 549 40 #330 of 549
Financial Health 46 #357 of 654 – 43 #372 of 654
Shareholder Returns 68 #120 of 367 – –
Overall 77 92 32
  • ALNY ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NXTS ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALNYARGXNXTSSPY
1 month -9.0%-8.3%-57.1% +0.9%
3 months -18.9%+1.0%-57.4% +5.9%
6 months -22.8%+14.9%-86.6% +8.5%
Year to date -41.6%+6.0%-94.6% +13.3%
1 year -51.2%+6.6%-97.4% +12.4%
3 years +53.1%+93.9%-99.9% +88.1%
3 years, per year +15.3%+24.7%-89.2% +23.5%
5 years +45.7%+195.3%-100.0% +68.2%
5 years, per year +7.8%+24.2%-85.8% +11.0%
10 years +539.5%—-100.0% +263.4%
10 years, per year +20.4%—-66.2% +13.8%

Risk

MeasureALNYARGXNXTSSPY
Volatility, 1Y 51.3%36.9%169.0% 12.7%
Downside volatility, 1Y 62.9%34.6%153.5% 12.7%
Beta vs S&P 500, 1Y 0.350.392.35 1.00
Return / volatility, 1Y -1.000.18-0.58 0.98
Max drawdown, 5Y -58.2%-38.2%-100.0% -25.4%
From 52-week high -51.7%-15.8%-97.4% -0.9%
52-week high $481.59$1,058.90$24.15 $779.14
52-week low $205.48$663.93$0.53 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALNYARGXNXTS
P/E now vs peer median 42.4xmedian 17.4x 29.1xmedian 17.4x 0.0xmedian 17.4x
P/S now vs peer median 6.5xmedian 9.1x 9.5xmedian 9.1x —median 9.1x
EV/EBITDA now vs peer median 26.3xmedian 17.1x —median 17.1x 1.5xmedian 17.1x
P/FCF now vs peer median 37.9xmedian 19.0x —median 19.0x —median 19.0x
P/B now vs peer median 23.0xmedian 2.2x —median 2.2x 0.3xmedian 2.2x
PEG now vs peer median 1.12median 0.34 0.28median 0.34 0.00median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALNYARGXNXTS
Revenue $4.80B $5.82B –
Gross profit $3.83B $5.24B –
Operating income $999.78M $1.74B -$5.28M
Net income $733.11M $1.88B -$14.06M
Free cash flow $819.87M – –
R&D $1.51B $1.80B $532.00K
EPS (diluted) $5.30 $28.43 $-17.10
Cash & equivalents $1.71B – $7.62M
Total debt – – $3.22M
Shares (diluted) 138.28M 66.03M 816.14K
Enterprise value $11.35B $55.00B -$22.13M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALNYARGXNXTS
P/E 42.4x 29.1x 0.0x
P/FCF 37.9x – –
P/Operating cash flow 34.1x – –
P/S 6.5x 9.5x –
P/B 23.0x – 0.3x
P/Tangible book 23.0x – -0.2x
EV/EBITDA 26.3x – 1.5x
EV/EBIT 27.8x 31.7x 1.5x
EV/Revenue 5.8x 9.5x –
EV/FCF 33.9x – –
EV/Operating cash flow 30.5x – –
PEG (3Y EPS CAGR) 1.12 0.28 0.00

Growth

14 metrics
MetricALNYARGXNXTS
Revenue growth (1Y) 90.1% 61.5% –
Revenue CAGR (3Y) 57.2% 80.5% –
Gross profit growth (1Y) 79.7% 62.2% –
Gross profit CAGR (3Y) 54.6% 80.0% –
Operating income growth (1Y) 654.9% 120.6% -7.7%
Operating income CAGR (3Y) 47.5% 85.1% 3.0%
Net income growth (1Y) 356.5% 22.5% -48.2%
Net income CAGR (3Y) 39.1% 115.5% -35.8%
EPS growth (1Y) 342.3% 20.9% -567.8%
EPS CAGR (3Y) 37.9% 104.8% -45.2%
Operating cash flow growth (1Y) 2,299% – –
Operating cash flow CAGR (3Y) 57.8% – –
Free cash flow growth (1Y) 1,151% – –
Free cash flow CAGR (3Y) 52.1% – –

Profitability

14 metrics
MetricALNYARGXNXTS
Gross margin 79.8% 90.0% –
EBITDA margin 22.0% – –
Operating margin 20.8% 29.9% –
Pretax margin 16.0% 32.6% –
Net margin 15.3% 32.3% –
FCF margin 17.1% – –
Operating cash flow margin 19.0% – –
Return on equity 63.8% – -157.0%
Return on assets 14.5% – -71.9%
Return on invested capital – – –
Return on capital employed 26.1% – -31.5%
Asset turnover 0.9x – –
Cash conversion (OCF / net income) 1.2x – –
Stock comp / revenue 7.0% – –

Financial Health

11 metrics
MetricALNYARGXNXTS
Debt / assets – – 2.3%
Debt / equity – – 0.2x
Net debt / EBITDA – – 1.6x
Debt / FCF – – –
Liabilities / assets 75.6% – 89.8%
Equity / assets 24.4% – 10.2%
Interest coverage 3.8x 10,120x –
Current ratio 3.1x – 3.7x
Quick ratio 2.8x – 3.2x
Cash ratio 2.2x – 3.2x
Altman Z-score 4.97 – –

Shareholder Returns

7 metrics
MetricALNYARGXNXTS
Dividend yield – – –
Net buyback yield -0.5% – –
Shareholder yield -0.5% – –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALNYARGXNXTS
Forward P/E 34.4xFY2026 29.1xFY2026 –
EPS, next fiscal year $6.76FY2026 $30.63FY2026 –
EPS growth, next FY +190.1%FY2026 +56.5%FY2026 –
EPS growth, the year after +34.3% +26.9% –
Revenue, next fiscal year $5.68BFY2026 $6.08BFY2026 –
Revenue growth, next FY +53.1%FY2026 +43.1%FY2026 –
Revenue growth, the year after +27.8% +22.9% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALNYARGXNXTS
Held by institutions 99.7% 46.1% –
Institutions holding 786 504 –
Change in shares held, QoQ +3.8% -2.0% –
Institutions buying 412 264 –
Institutions selling 277 160 –
Buyers to sellers 1.49 1.65 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALNYARGXNXTS
ALNY 1.00 0.19 0.03
ARGX 0.19 1.00 0.12
NXTS 0.03 0.12 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ALNY, ARGX and NXTS?

Argenx Se (ARGX) is the largest by market capitalisation: Alnylam Pharmaceuticals (ALNY) $23.30B, Argenx Se (ARGX) $55.00B, Nexentis Technologies (NXTS) $514.98K.

Which stock is cheaper, ALNY, ARGX and NXTS?

Argenx Se (ARGX) trades on the lowest price-to-earnings ratio (Alnylam Pharmaceuticals (ALNY) 31.8x, Argenx Se (ARGX) 29.3x, Nexentis Technologies (NXTS) 0.0x). On next year's consensus earnings, Argenx Se (ARGX) is cheapest (Alnylam Pharmaceuticals (ALNY) 34.4x, Argenx Se (ARGX) 29.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Alnylam Pharmaceuticals (ALNY) +90.1%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Alnylam Pharmaceuticals (ALNY) 15.3%, Argenx Se (ARGX) 32.3%).

Which stock has performed better?

Over the past year Argenx Se (ARGX) returned the most: Alnylam Pharmaceuticals (ALNY) -51.2%, Argenx Se (ARGX) +6.6%, Nexentis Technologies (NXTS) -97.4%. Over five years, Argenx Se (ARGX) compounded fastest (Alnylam Pharmaceuticals (ALNY) +7.8%/yr, Argenx Se (ARGX) +24.2%/yr, Nexentis Technologies (NXTS) -85.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Argenx Se (ARGX) has been the steadiest (Alnylam Pharmaceuticals (ALNY) 51.3%, Argenx Se (ARGX) 36.9%, Nexentis Technologies (NXTS) 169.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALNY, ARGX and NXTS?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.