ALNY vs ARGX vs NXTS Stock Comparison

Alnylam Pharmaceuticals, Argenx Se and Nexentis Technologies Prices as of Nov 2, 2026 Peers: Industry group
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ARGX Argenx Se
$874.97 -4.8% 1M +6.9% 1Y
Market cap
$56.40B
P/E
30.0x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
6 wins

Head to Head

10 decided of 12

Argenx Se leads on 6 of the 12 questions below (Argenx Se 6, Alnylam Pharmaceuticals 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALNYARGXNXTSLeader
Larger companyMarket capitalisation $21.78B $56.40B $440.71K ARGX
Cheaper on earningsLower P/E, profitable companies only 8.2x 30.0x 0.0x ALNY
Cheaper on forward earningsLower price / next fiscal year consensus EPS 23.7x 29.4x — ALNY
Faster revenue growthRevenue growth, trailing twelve months +60.8% +61.5% — ARGX
More profitableNet margin, trailing twelve months 52.8% 32.3% — ALNY
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA -3.1x — 1.6x ALNY
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -65.4% +6.9% -97.8% ARGX
Better 5-year returnAnnualised price return, 5 years -1.8%/yr +22.1%/yr -86.6%/yr ARGX
Less volatileAnnualised volatility, 1 year 58.7% 37.0% 169.7% ARGX
Higher overall scoreMean of the five percentile scores vs peers 82/100 92/100 32/100 ARGX

Percentile Scorecard

ALNYARGXNXTS

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALNYARGXNXTS
Valuation 91 #55 of 623 84 #103 of 623 –
Growth 99 #8 of 601 94 #35 of 601 13 #523 of 601
Profitability 90 #56 of 553 98 #11 of 553 40 #331 of 553
Financial Health 62 #249 of 654 – 43 #373 of 654
Shareholder Returns 69 #114 of 367 – –
Overall 82 92 32
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • NXTS ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALNYARGXNXTSSPY
1 month -28.1%-4.8%-63.2% -2.3%
3 months -28.3%+5.3%-74.4% -0.7%
6 months -47.0%+7.9%-88.4% +4.8%
Year to date -60.3%+4.0%-95.5% +10.3%
1 year -65.4%+6.9%-97.8% +10.3%
3 years -5.6%+75.0%-99.9% +73.0%
3 years, per year -1.9%+20.5%-90.5% +20.1%
5 years -8.6%+170.8%-100.0% +61.9%
5 years, per year -1.8%+22.1%-86.6% +10.1%
10 years +339.5%—-100.0% +258.6%
10 years, per year +16.0%—-66.8% +13.6%

Risk

MeasureALNYARGXNXTSSPY
Volatility, 1Y 58.7%37.0%169.7% 12.8%
Downside volatility, 1Y 74.5%34.8%154.9% 12.8%
Beta vs S&P 500, 1Y 0.440.402.41 1.00
Return / volatility, 1Y -1.110.19-0.58 0.80
Max drawdown, 5Y -67.8%-38.2%-100.0% -25.4%
From 52-week high -66.6%-17.4%-97.7% -3.5%
52-week high $473.29$1,058.90$23.38 $779.14
52-week low $158.00$663.93$0.53 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALNYARGXNXTS
P/E now vs peer median 8.0xmedian 17.4x 28.6xmedian 17.4x 0.0xmedian 17.4x
P/S now vs peer median 4.2xmedian 8.9x 9.3xmedian 8.9x —median 8.9x
EV/EBITDA now vs peer median 17.3xmedian 17.0x —median 17.0x 1.5xmedian 17.0x
P/FCF now vs peer median 26.2xmedian 21.4x —median 21.4x —median 21.4x
P/B now vs peer median 5.9xmedian 2.1x —median 2.1x 0.2xmedian 2.1x
PEG now vs peer median 0.09median 0.35 0.27median 0.35 0.00median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALNYARGXNXTS
Revenue $5.01B $5.82B –
Gross profit $3.88B $5.24B –
Operating income $977.59M $1.74B -$5.28M
Net income $2.65B $1.88B -$14.06M
Free cash flow $806.31M – –
R&D $1.56B $1.80B $532.00K
EPS (diluted) $19.16 $28.43 $-17.10
Cash & equivalents $1.75B – $7.62M
Total debt $361.53M – $422.00K
Shares (diluted) 138.28M 66.03M 816.14K
Enterprise value $8.96B $56.40B -$22.20M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALNYARGXNXTS
P/E 8.0x 28.6x 0.0x
P/FCF 26.2x – –
P/Operating cash flow 22.1x – –
P/S 4.2x 9.3x –
P/B 5.9x – 0.2x
P/Tangible book 5.9x – -0.2x
EV/EBITDA 17.3x – 1.5x
EV/EBIT 18.3x 31.1x 1.5x
EV/Revenue 3.6x 9.3x –
EV/FCF 22.2x – –
EV/Operating cash flow 18.7x – –
PEG (3Y EPS CAGR) 0.09 0.27 0.00

Growth

14 metrics
MetricALNYARGXNXTS
Revenue growth (1Y) 60.8% 61.5% –
Revenue CAGR (3Y) 42.7% 80.5% –
Gross profit growth (1Y) 49.6% 62.2% –
Gross profit CAGR (3Y) 37.8% 80.0% –
Operating income growth (1Y) 269.3% 120.6% -7.7%
Operating income CAGR (3Y) 68.2% 85.1% 3.0%
Net income growth (1Y) 2,137% 22.5% -48.2%
Net income CAGR (3Y) 93.1% 115.5% -35.8%
EPS growth (1Y) 2,122% 20.9% -567.8%
EPS CAGR (3Y) 90.7% 104.8% -45.2%
Operating cash flow growth (1Y) 351.6% – –
Operating cash flow CAGR (3Y) 685.4% – –
Free cash flow growth (1Y) 382.3% – –
Free cash flow CAGR (3Y) 141.7% – –

Profitability

14 metrics
MetricALNYARGXNXTS
Gross margin 77.4% 90.0% –
EBITDA margin 20.6% – –
Operating margin 19.5% 29.9% –
Pretax margin 15.6% 32.6% –
Net margin 52.8% 32.3% –
FCF margin 16.1% – –
Operating cash flow margin 19.1% – –
Return on equity 106.9% – -157.0%
Return on assets 39.1% – -71.9%
Return on invested capital – – –
Return on capital employed 20.7% – -31.5%
Asset turnover 0.7x – –
Cash conversion (OCF / net income) 0.4x – –
Stock comp / revenue 6.1% – –

Financial Health

11 metrics
MetricALNYARGXNXTS
Debt / assets 4.5% – 2.3%
Debt / equity 0.1x – 0.2x
Net debt / EBITDA -3.1x – 1.6x
Debt / FCF 0.4x – –
Liabilities / assets 54.9% – 89.8%
Equity / assets 45.1% – 10.2%
Interest coverage 3.2x 10,120x –
Current ratio 2.5x – 3.7x
Quick ratio 2.3x – 3.2x
Cash ratio 1.7x – 3.2x
Altman Z-score 3.65 – –

Shareholder Returns

7 metrics
MetricALNYARGXNXTS
Dividend yield – – –
Net buyback yield -0.5% – –
Shareholder yield -0.5% – –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALNYARGXNXTS
Forward P/E 23.7xFY2026 29.4xFY2026 –
EPS, next fiscal year $6.76FY2026 $30.63FY2026 –
EPS growth, next FY +190.1%FY2026 +56.5%FY2026 –
EPS growth, the year after +34.3% +26.9% –
Revenue, next fiscal year $5.68BFY2026 $6.08BFY2026 –
Revenue growth, next FY +53.1%FY2026 +43.1%FY2026 –
Revenue growth, the year after +27.8% +22.9% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALNYARGXNXTS
Held by institutions 99.7% 46.1% –
Institutions holding 788 506 –
Change in shares held, QoQ +3.8% -2.0% –
Institutions buying 412 264 –
Institutions selling 279 162 –
Buyers to sellers 1.48 1.63 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALNYARGXNXTS
ALNY 1.00 0.16 0.03
ARGX 0.16 1.00 0.12
NXTS 0.03 0.12 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ALNY, ARGX and NXTS?

Argenx Se (ARGX) is the largest by market capitalisation: Alnylam Pharmaceuticals (ALNY) $21.78B, Argenx Se (ARGX) $56.40B, Nexentis Technologies (NXTS) $440.71K.

Which stock is cheaper, ALNY, ARGX and NXTS?

Alnylam Pharmaceuticals (ALNY) trades on the lowest price-to-earnings ratio (Alnylam Pharmaceuticals (ALNY) 8.2x, Argenx Se (ARGX) 30.0x, Nexentis Technologies (NXTS) 0.0x). On next year's consensus earnings, Alnylam Pharmaceuticals (ALNY) is cheapest (Alnylam Pharmaceuticals (ALNY) 23.7x, Argenx Se (ARGX) 29.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Alnylam Pharmaceuticals (ALNY) +60.8%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Alnylam Pharmaceuticals (ALNY) has the highest net margin (Alnylam Pharmaceuticals (ALNY) 52.8%, Argenx Se (ARGX) 32.3%).

Which stock has performed better?

Over the past year Argenx Se (ARGX) returned the most: Alnylam Pharmaceuticals (ALNY) -65.4%, Argenx Se (ARGX) +6.9%, Nexentis Technologies (NXTS) -97.8%. Over five years, Argenx Se (ARGX) compounded fastest (Alnylam Pharmaceuticals (ALNY) -1.8%/yr, Argenx Se (ARGX) +22.1%/yr, Nexentis Technologies (NXTS) -86.6%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Argenx Se (ARGX) has been the steadiest (Alnylam Pharmaceuticals (ALNY) 58.7%, Argenx Se (ARGX) 37.0%, Nexentis Technologies (NXTS) 169.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ALNY, ARGX and NXTS?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.