ALNY vs GILD Stock Comparison

Alnylam Pharmaceuticals and Gilead Sciences Prices as of Oct 23, 2026 Peers: Industry group
GILD Gilead Sciences, Inc.
$156.04 +3.1% 1M +29.2% 1Y
Market cap
$197.28B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
4 wins

Head to Head

7 decided of 12

Gilead Sciences leads on 4 of the 12 questions below (Gilead Sciences 4, Alnylam Pharmaceuticals 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionALNYGILDLeader
Larger companyMarket capitalisation $30.46B $197.28B GILD
Cheaper on earningsLower P/E, profitable companies only 41.6x -60.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 32.4x — –
Faster revenue growthRevenue growth, trailing twelve months +90.1% +5.5% ALNY
More profitableNet margin, trailing twelve months 15.3% -10.6% ALNY
Better return on capitalReturn on invested capital — -6.0% –
Less leveragedLower net debt / EBITDA — 87.7x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -51.7% +29.2% GILD
Better 5-year returnAnnualised price return, 5 years +2.4%/yr +18.4%/yr GILD
Less volatileAnnualised volatility, 1 year 51.3% 26.9% GILD
Higher overall scoreMean of the five percentile scores vs peers 77/100 61/100 ALNY

Percentile Scorecard

ALNYGILD

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisALNYGILD
Valuation 81 #122 of 624 90 #62 of 624
Growth 98 #12 of 603 31 #419 of 603
Profitability 93 #40 of 555 85 #84 of 555
Financial Health 45 #359 of 657 21 #518 of 657
Shareholder Returns 67 #123 of 370 77 #86 of 370
Overall 77 61
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology
  • GILD ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodALNYGILDSPY
1 month -9.1%+3.1% -1.0%
3 months -17.6%+20.7% +2.9%
6 months -26.7%+19.7% +6.4%
Year to date -43.7%+27.1% +11.4%
1 year -51.7%+29.2% +13.1%
3 years +36.6%+99.7% +79.4%
3 years, per year +11.0%+25.9% +21.5%
5 years +12.8%+132.1% +67.7%
5 years, per year +2.4%+18.4% +10.9%
10 years +510.9%+110.0% +255.2%
10 years, per year +19.8%+7.7% +13.5%

Risk

MeasureALNYGILDSPY
Volatility, 1Y 51.3%26.9% 12.7%
Downside volatility, 1Y 62.6%23.9% 12.7%
Beta vs S&P 500, 1Y 0.360.29 1.00
Return / volatility, 1Y -1.011.09 1.03
Max drawdown, 5Y -58.2%-29.4% -25.4%
From 52-week high -53.5%-0.8% -2.5%
52-week high $481.59$157.37 $779.14
52-week low $205.48$117.88 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleALNYGILD
P/E now vs peer median 40.8xmedian 17.2x -59.9xmedian 17.2x
P/S now vs peer median 6.2xmedian 8.8x 6.4xmedian 8.8x
EV/EBITDA now vs peer median 25.3xmedian 16.0x 824.0xmedian 16.0x
P/FCF now vs peer median 36.5xmedian 17.8x 15.0xmedian 17.8x
P/B now vs peer median 22.1xmedian 2.1x 16.4xmedian 2.1x
PEG now vs peer median 1.08median 0.32 1.60median 0.32

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsALNYGILD
Revenue $4.80B $30.46B
Gross profit $3.83B $24.24B
Operating income $999.78M -$2.50B
Net income $733.11M -$3.24B
Free cash flow $819.87M $12.94B
R&D $1.51B $6.07B
EPS (diluted) $5.30 $-2.61
Cash & equivalents $1.71B $3.18B
Total debt – $26.25B
Shares (diluted) 138.28M 1.24B
Enterprise value $18.51B $171.47B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricALNYGILD
P/E 40.8x -59.9x
P/FCF 36.5x 15.0x
P/Operating cash flow 32.9x 14.3x
P/S 6.2x 6.4x
P/B 22.1x 16.4x
P/Tangible book 22.1x -87.9x
EV/EBITDA 25.3x 824.0x
EV/EBIT 26.7x -86.8x
EV/Revenue 5.5x 7.1x
EV/FCF 32.5x 16.7x
EV/Operating cash flow 29.2x 16.0x
PEG (3Y EPS CAGR) 1.08 1.60

Growth

14 metrics
MetricALNYGILD
Revenue growth (1Y) 90.1% 5.5%
Revenue CAGR (3Y) 57.2% 3.6%
Gross profit growth (1Y) 79.7% 6.9%
Gross profit CAGR (3Y) 54.6% 3.7%
Operating income growth (1Y) 654.9% -131.0%
Operating income CAGR (3Y) 47.5% -31.9%
Net income growth (1Y) 356.5% -151.3%
Net income CAGR (3Y) 39.1% -37.3%
EPS growth (1Y) 342.3% -151.8%
EPS CAGR (3Y) 37.9% -37.5%
Operating cash flow growth (1Y) 2,299% 37.3%
Operating cash flow CAGR (3Y) 57.8% 12.5%
Free cash flow growth (1Y) 1,151% 38.1%
Free cash flow CAGR (3Y) 52.1% 13.2%

Profitability

14 metrics
MetricALNYGILD
Gross margin 79.8% 79.6%
EBITDA margin 22.0% 0.9%
Operating margin 20.8% -8.2%
Pretax margin 16.0% -6.4%
Net margin 15.3% -10.6%
FCF margin 17.1% 42.5%
Operating cash flow margin 19.0% 44.5%
Return on equity 63.8% -18.4%
Return on assets 14.5% -6.1%
Return on invested capital – -6.0%
Return on capital employed 26.1% -6.0%
Asset turnover 0.9x 0.6x
Cash conversion (OCF / net income) 1.2x -4.2x
Stock comp / revenue 7.0% 3.0%

Financial Health

11 metrics
MetricALNYGILD
Debt / assets – 53.2%
Debt / equity – 2.2x
Net debt / EBITDA – 87.7x
Debt / FCF – 2.0x
Liabilities / assets 75.6% 76.0%
Equity / assets 24.4% 24.0%
Interest coverage 3.8x -2.5x
Current ratio 3.1x 1.3x
Quick ratio 2.8x 0.7x
Cash ratio 2.2x 0.3x
Altman Z-score 4.81 3.68

Shareholder Returns

7 metrics
MetricALNYGILD
Dividend yield – 2.1%
Net buyback yield -0.6% 0.6%
Shareholder yield -0.6% 2.7%
Payout ratio (earnings) – –
Payout ratio (FCF) – –
Dividend growth (1Y) – –
Dividend CAGR (3Y) – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusALNYGILD
Forward P/E 32.4xFY2026 –
EPS, next fiscal year $6.92FY2026 $-0.39FY2026
EPS growth, next FY +197.0%FY2026 -104.8%FY2026
EPS growth, the year after +34.0% –
Revenue, next fiscal year $5.68BFY2026 $28.60BFY2026
Revenue growth, next FY +53.1%FY2026 -2.9%FY2026
Revenue growth, the year after +27.4% +18.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersALNYGILD
Held by institutions 99.7% 89.6%
Institutions holding 786 2,290
Change in shares held, QoQ +3.8% +5.1%
Institutions buying 412 1,113
Institutions selling 277 850
Buyers to sellers 1.49 1.31

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ALNYGILD
ALNY 1.00 0.26
GILD 0.26 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, ALNY and GILD?

Gilead Sciences (GILD) is the largest by market capitalisation: Alnylam Pharmaceuticals (ALNY) $30.46B, Gilead Sciences (GILD) $197.28B.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Alnylam Pharmaceuticals (ALNY) +90.1%, Gilead Sciences (GILD) +5.5%.

Which company is more profitable?

Alnylam Pharmaceuticals (ALNY) has the highest net margin (Alnylam Pharmaceuticals (ALNY) 15.3%, Gilead Sciences (GILD) -10.6%).

Which stock has performed better?

Over the past year Gilead Sciences (GILD) returned the most: Alnylam Pharmaceuticals (ALNY) -51.7%, Gilead Sciences (GILD) +29.2%. Over five years, Gilead Sciences (GILD) compounded fastest (Alnylam Pharmaceuticals (ALNY) +2.4%/yr, Gilead Sciences (GILD) +18.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Alnylam Pharmaceuticals (ALNY) 51.3%, Gilead Sciences (GILD) 26.9%). Volatility measures how widely the price swings, not the risk of the business.

Do ALNY and GILD move together?

Their daily returns over the past year have a correlation of 0.26, a weak relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, ALNY and GILD?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Gilead Sciences (GILD) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.