Zentalis Pharmaceuticals (ZNTL) Return on Capital Employed (2020 - 2026)

Zentalis Pharmaceuticals' quarterly Return on Capital Employed came in at 61.51% in Q1 2026, down 224.0% year-on-year from 49.61% in Q1 2025, and down 9.32% quarter-over-quarter from 56.27% in Q4 2025.

Zentalis Pharmaceuticals has reported Return on Capital Employed for 7 years, with the latest figure at 61.51% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Capital Employed fell 224.0% year-over-year to 61.51%; the trailing twelve-month figure through Mar 2026 stood at 61.51% (down 224.0% YoY), and the FY2025 full-year result was 47.3%, down 367.0% from the prior year.
  • Return on Capital Employed for Q1 2026 stood at 61.51%, down from 56.27% in the prior quarter.
  • The five-year high for Return on Capital Employed was 45.25% in Q3 2022, with the low at 61.51% in Q1 2026.
  • Average Return on Capital Employed over 5 years is 53.45%, with a median of 53.04% recorded in 2022.
  • Year-over-year, Return on Capital Employed soared 1992 bps in 2022 and tumbled 1239 bps in 2023.
  • Tracing ZNTL's Return on Capital Employed over 5 years: stood at 47.59% in 2022, then decreased by 26 bps to 59.98% in 2023, then advanced by 18 bps to 49.31% in 2024, then fell by 14 bps to 56.27% in 2025, then decreased by 9 bps to 61.51% in 2026.
  • The last three Return on Capital Employed figures came in at 61.51% (Q1 2026), 56.27% (Q4 2025), and 54.67% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 450.31%
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -107.40%
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 21.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 20.34%
10 Zentalis Pharmaceuticals 280.35 Mn 280.35 Mn - -61.51%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -61.51%
Dec 31, 2025 -56.27%
Sep 30, 2025 -54.67%
Jun 30, 2025 -55.64%
Mar 31, 2025 -59.27%
Dec 31, 2024 -49.31%
Sep 30, 2024 -50.27%
Jun 30, 2024 -48.17%
Mar 31, 2024 -51.89%
Dec 31, 2023 -59.98%
Sep 30, 2023 -52.02%
Jun 30, 2023 -54.57%
Mar 31, 2023 -51.17%
Dec 31, 2022 -47.59%
Sep 30, 2022 -45.25%
Jun 30, 2022 -53.04%
Mar 31, 2022 -57.96%
Dec 31, 2021 -54.02%
Sep 30, 2021 -65.16%
Jun 30, 2021 -66.22%
Mar 31, 2021 -48.62%
Dec 31, 2020 -33.86%
Sep 30, 2020 -31.01%
Jun 30, 2020 -45.43%
Mar 31, 2020 -77.21%