Zentalis Pharmaceuticals (ZNTL) Return on Capital Employed (2020 - 2026)

Zentalis Pharmaceuticals' (ZNTL) quarterly Return on Capital Employed came in at 61.51% in Q1 2026, down 224.0% year-on-year from 49.61% in Q1 2025, and down 9.32% quarter-over-quarter from 56.27% in Q4 2025.

Zentalis Pharmaceuticals (ZNTL) Return on Capital Employed (2020 - 2026) Analysis & Trends

Zentalis Pharmaceuticals' Return on Capital Employed history runs 7 years deep, the most recent figure standing at 61.51% for Q1 2026.

  • On a quarterly basis, Return on Capital Employed fell 224.0% year-over-year to 61.51% in Q1 2026; TTM through Mar 2026 was 61.51%, a 224.0% decrease from a year earlier, with the FY2025 full-year figure at 47.3%, down 367.0% from the prior year.
  • Return on Capital Employed declined to 61.51% in Q1 2026 per ZNTL's latest filing, from 56.27% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 45.25% in Q3 2022 and bottomed at 61.51% in Q1 2026.
  • The 5-year median for Return on Capital Employed is 53.04% (2022), against an average of 53.45%.
  • Across the five-year window, Return on Capital Employed soared 1992 bps in 2022 and tumbled 1239 bps in 2023, its largest moves.
  • Year by year, Return on Capital Employed stood at 47.59% in 2022, then retreated by 26 bps to 59.98% in 2023, then gained by 18 bps to 49.31% in 2024, then declined by 14 bps to 56.27% in 2025, then retreated by 9 bps to 61.51% in 2026.
  • Per Business Quant, the three latest ZNTL Return on Capital Employed figures stand at 61.51% (Q1 2026), 56.27% (Q4 2025), and 54.67% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Zentalis Pharmaceuticals 312.67 Mn 312.67 Mn - -61.51%

Historic Data

Download Data
DateValue
Mar 31, 2026 -61.51%
Dec 31, 2025 -56.27%
Sep 30, 2025 -54.67%
Jun 30, 2025 -55.64%
Mar 31, 2025 -59.27%
Dec 31, 2024 -49.31%
Sep 30, 2024 -50.27%
Jun 30, 2024 -48.17%
Mar 31, 2024 -51.89%
Dec 31, 2023 -59.98%
Sep 30, 2023 -52.02%
Jun 30, 2023 -54.57%
Mar 31, 2023 -51.17%
Dec 31, 2022 -47.59%
Sep 30, 2022 -45.25%
Jun 30, 2022 -53.04%
Mar 31, 2022 -57.96%
Dec 31, 2021 -54.02%
Sep 30, 2021 -65.16%
Jun 30, 2021 -66.22%