Cash Flow Statement
Growth Metrics

22nd Century (XXII) Operating Margin (2016 - 2026)

22nd Century's Operating Margin history spans 16 years, with the latest figure at 79.25% for Q4 2025.

  • On a quarterly basis, Operating Margin rose 257789.0% to 79.25% in Q4 2025 year-over-year; TTM through Dec 2025 was 65.76%, a 223.0% increase, with the full-year FY2025 number at 65.76%, down 855.0% from a year prior.
  • Operating Margin hit 79.25% in Q4 2025 for 22nd Century, up from 80.08% in the prior quarter.
  • Over the last five years, Operating Margin for XXII hit a ceiling of 2.57% in Q4 2022 and a floor of 2657.14% in Q4 2024.
  • Historically, Operating Margin has averaged 217.31% across 5 years, with a median of 87.53% in 2021.
  • Biggest five-year swings in Operating Margin: tumbled -246369bps in 2024 and later soared 257789bps in 2025.
  • Tracing XXII's Operating Margin over 5 years: stood at 132.71% in 2021, then soared by 102bps to 2.57% in 2022, then tumbled by -7620bps to 193.45% in 2023, then tumbled by -1274bps to 2657.14% in 2024, then skyrocketed by 97bps to 79.25% in 2025.
  • Business Quant data shows Operating Margin for XXII at 79.25% in Q4 2025, 80.08% in Q3 2025, and 73.01% in Q2 2025.