Xilio Therapeutics (XLO) Return on Equity [ROE] (2021 - 2026)
Xilio Therapeutics' Return on Equity [ROE] was -43.32% in Q2 2026, up 593.83 percentage points from -637.15% a year earlier and up 35.04 percentage points from the prior quarter.
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Analysis
Xilio Therapeutics (XLO) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, Return on Equity [ROE] at Xilio Therapeutics came in at -158.81%, up 63.82 percentage points from FY2024.
- Return on Equity [ROE] shows a four-year change of -11.87 percentage points (FY2021 to FY2025).
- In earlier years, Return on Equity [ROE] was -222.63% in FY2024 (-111.54 pp), -111.08% in FY2023 (-49.83 pp), -61.25% in FY2022 (+85.69 pp) and -146.94% in FY2021.
- The Q2 2026 figure marks the highest quarterly Return on Equity [ROE] in data going back to Q4 2021.
- Compared with a year earlier, Return on Equity [ROE] has increased for three straight quarters, with an average year-over-year change of +15.71 percentage points over the last seven quarters.
- The best year-over-year quarter for Return on Equity [ROE] over five years was Q2 2026 (a gain of 593.83 percentage points); the worst was Q2 2025 (a drop of 408.43 percentage points).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 74.39% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | - |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 5.63% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 21.60% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 72.13% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -31.17% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 4.66% |
| 10 | Xilio Therapeutics | 167.94 Mn | -378.15 Mn | - | -58.63% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -58.63% |
| Jun 30, 2026 | -43.32% |
| Mar 31, 2026 | -78.36% |
| Dec 31, 2025 | -304.63% |
| Jun 30, 2025 | -616.17% |
| Mar 31, 2025 | -383.79% |
| Dec 31, 2024 | -301.99% |
| Sep 30, 2024 | -230.94% |
| Jun 30, 2024 | -221.46% |
| Mar 31, 2024 | -226.74% |
| Dec 31, 2023 | -171.07% |
| Sep 30, 2023 | -135.50% |
| Jun 30, 2023 | -110.74% |
| Mar 31, 2023 | -94.01% |
| Dec 31, 2022 | -76.07% |
| Sep 30, 2022 | -63.18% |
| Jun 30, 2022 | -52.79% |
| Mar 31, 2022 | -45.79% |
| Dec 31, 2021 | -309.55% |
API Access
Xilio Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();