Xilio Therapeutics XLO
NASDAQ XLO
$8.99 +0.02 (+0.28%)
As of: Sep 10, 2026 · 1:21 PM EDT

Xilio Therapeutics (XLO) Operating Income (2020 - 2026)

Xilio Therapeutics' (XLO) quarterly Operating Income came in at -$3.5 million in Q2 2026, up 75.7% year-over-year from -$2.0 million in Q2 2025, and up 75.26% quarter-over-quarter from -$14.1 million in Q1 2026.

Analysis

Xilio Therapeutics (XLO) Operating Income (2020 - 2026) Analysis & Trends

Xilio Therapeutics has disclosed Operating Income across 7 years of filings, most recently posting -$3.5 million for Q2 2026.

  • In Q2 2026, Operating Income rose 75.7% year-over-year to -$3.5 million; the TTM figure through Jun 2026 stood at -$31.4 million (up 44.59% YoY), while the FY2025 annual figure was -$42.0 million, up 30.7% from the prior year.
  • Operating Income came in at -$3.5 million for Q2 2026 at Xilio Therapeutics, up from -$14.1 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$1.9 million in Q3 2025 to a low of -$24.6 million in Q2 2022.
  • Average Operating Income over 5 years is -$16.0 million, with a median of -$16.1 million recorded in 2023.
  • Year-over-year, Operating Income slipped 28.47% in 2022 and soared 86.93% in 2025.
  • Over 5 years, Operating Income stood at -$23.2 million in 2022, then grew by 21.74% to -$18.1 million in 2023, then rose by 24.83% to -$13.6 million in 2024, then rose by 13.16% to -$11.8 million in 2025, then jumped by 70.51% to -$3.5 million in 2026.
  • Per Business Quant data, the three most recent Operating Income figures were -$3.5 million in Q2 2026, -$14.1 million in Q1 2026, and -$11.8 million in Q4 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Amgen 206.44 Bn 192.45 Bn 7.24 Bn 3.51 Bn
2 Gilead Sciences 179.97 Bn 176.79 Bn 6.22 Bn -10.39 Bn
3 Vertex Pharmaceuticals 130.57 Bn 122.72 Bn 2.84 Bn 1.25 Bn
4 Regeneron Pharmaceuticals 81.63 Bn 73.63 Bn 3.93 Bn 1.29 Bn
5 Argenx Se 60.34 Bn 55.16 Bn 1.37 Bn 493.00 Mn
6 Moderna 54.37 Bn 49.23 Bn 52.00 Mn -815.00 Mn
7 Alnylam Pharmaceuticals 33.07 Bn 29.76 Bn 992.69 Mn 231.44 Mn
8 Biogen 31.84 Bn 30.55 Bn 1.96 Bn -644.50 Mn
9 Roivant Sciences 29.49 Bn 29.49 Bn 1.16 Mn -365.99 Mn
10 Xilio Therapeutics 174.55 Mn 38.51 Mn - -3.49 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -3.49 Mn
Mar 31, 2026 -14.11 Mn
Dec 31, 2025 -11.84 Mn
Sep 30, 2025 -1.93 Mn
Jun 30, 2025 -14.37 Mn
Mar 31, 2025 -13.85 Mn
Dec 31, 2024 -13.63 Mn
Sep 30, 2024 -14.76 Mn
Jun 30, 2024 -14.70 Mn
Mar 31, 2024 -17.49 Mn
Dec 31, 2023 -18.13 Mn
Sep 30, 2023 -17.36 Mn
Jun 30, 2023 -20.12 Mn
Mar 31, 2023 -23.53 Mn
Dec 31, 2022 -23.17 Mn
Sep 30, 2022 -20.21 Mn
Jun 30, 2022 -24.55 Mn
Mar 31, 2022 -21.22 Mn
Dec 31, 2021 -19.56 Mn
Sep 30, 2021 -15.96 Mn