Xilio Therapeutics (XLO) Net Margin (2024 - 2026)
Xilio Therapeutics (XLO) recorded Net Margin of -18.68% in Q2 2026, up 159.03 percentage points from -177.71% a year earlier and up 92.90 percentage points from the prior quarter.
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Xilio Therapeutics (XLO) Net Margin (2024 - 2026) Analysis & Trends
On a TTM basis, Xilio Therapeutics' Net Margin came in at -48.94% as of Jun 30, 2026, up 316.23 percentage points year-over-year; for FY2025, it came in at -95.92%, up 822.12 percentage points from FY2024.
- Across earlier years, Net Margin came in at -918.05% in FY2024.
- Quarterly Net Margin has ranged from -759.45% in Q4 2024 to -10.12% in Q3 2025 over the past five years.
- On a year-over-year basis, Net Margin has increased for five consecutive quarters, with an average year-over-year change of +439.37 percentage points over the last five quarters.
- Per Business Quant, the preceding three quarters came in at -111.57% (Q1 2026), -86.48% (Q4 2025) and -10.12% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 30.88% |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 21.86% |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 21.27% |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | -8.04% |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 22.65% |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 16.30% |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 23.62% |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | -134.51% |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | -1.65% |
| 10 | Xilio Therapeutics | 162.81 Mn | -364.86 Mn | - | -18.68% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -18.68% |
| Mar 31, 2026 | -111.57% |
| Dec 31, 2025 | -86.48% |
| Sep 30, 2025 | -10.12% |
| Jun 30, 2025 | -177.71% |
| Mar 31, 2025 | -453.92% |
| Dec 31, 2024 | -759.45% |
| Sep 30, 2024 | -619.53% |
| Jun 30, 2024 | -590.79% |
API Access
Xilio Therapeutics Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();