Xilio Therapeutics (XLO) Net Cash Flow (2020 - 2026)

Xilio Therapeutics (XLO) reported Net Cash Flow of $12.8 million for Q1 2026, down 62.09% on a YoY basis from $33.8 million in Q1 2025, and down 62.08% sequentially from $33.8 million in Q4 2025.

Xilio Therapeutics (XLO) Net Cash Flow (2020 - 2026) Analysis & Trends

Xilio Therapeutics (XLO) has 7 years of Net Cash Flow data on file, last reported at $12.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Net Cash Flow fell 62.09% year-over-year to $12.8 million; the trailing twelve-month figure through Mar 2026 stood at $61.3 million (up 13.2% YoY), and the FY2025 full-year result was $82.3 million, up 662.98% from the prior year.
  • Net Cash Flow declined to $12.8 million in Q1 2026, from $33.8 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $40.0 million in Q2 2024 to a low of -$27.1 million in Q1 2023.
  • A 5-year average of -$2.8 million and a median of -$15.1 million in 2023 frame the typical range for Net Cash Flow.
  • Across the five-year window, Net Cash Flow tumbled 119.08% in 2022 and soared 666.57% in 2025, its largest moves.
  • Tracing XLO's Net Cash Flow over 5 years: stood at -$18.8 million in 2022, then grew by 19.69% to -$15.1 million in 2023, then surged by 60.42% to -$6.0 million in 2024, then soared by 666.57% to $33.8 million in 2025, then plunged by 62.08% to $12.8 million in 2026.
  • Business Quant data shows XLO's Net Cash Flow at $12.8 million in Q1 2026, $33.8 million in Q4 2025, and -$17.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Oculis Holding AG 67,102.16 Bn 67,101.87 Bn - 10.56 Mn
2 Nanobiotix 1,909.44 Bn 1,909.38 Bn - -
3 Akari Therapeutics 989.71 Bn 989.71 Bn - -2.44 Mn
4 BeOne Medicines 471.58 Bn 466.79 Bn 1.35 Bn 224.46 Mn
5 Vertex Pharmaceuticals 121.97 Bn 114.72 Bn 2.59 Bn 457.40 Mn
6 Regeneron Pharmaceuticals 69.93 Bn 61.18 Bn 3.31 Bn -152.20 Mn
7 Belite Bio 62.68 Bn 62.68 Bn - -
8 Argenx Se 55.80 Bn 50.61 Bn 1.41 Bn -
9 Alnylam Pharmaceuticals 37.37 Bn 34.36 Bn 959.66 Mn 60.68 Mn
10 Xilio Therapeutics 144.68 Mn -5.62 Mn - 12.81 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 12.81 Mn
Mar 31, 2026 12.81 Mn
Dec 31, 2025 33.77 Mn
Dec 31, 2025 33.77 Mn
Sep 30, 2025 -17.78 Mn
Sep 30, 2025 -17.78 Mn
Jun 30, 2025 32.48 Mn
Jun 30, 2025 32.48 Mn
Mar 31, 2025 33.79 Mn
Mar 31, 2025 33.79 Mn
Dec 31, 2024 -5.96 Mn
Dec 31, 2024 -5.96 Mn
Sep 30, 2024 -13.68 Mn
Sep 30, 2024 -13.68 Mn
Jun 30, 2024 40.00 Mn
Jun 30, 2024 40.00 Mn
Mar 31, 2024 -9.55 Mn
Mar 31, 2024 -9.55 Mn
Dec 31, 2023 -15.06 Mn
Dec 31, 2023 -15.06 Mn