Xilio Therapeutics (XLO) Free Cash Flow (2020 - 2026)
Xilio Therapeutics (XLO) reported Free Cash Flow of -$22.9 million for Q1 2026, down 179.83% on a YoY basis from $28.7 million in Q1 2025, and down 1034.74% sequentially from -$2.0 million in Q4 2025.
Xilio Therapeutics (XLO) Free Cash Flow (2020 - 2026) Analysis & Trends
Xilio Therapeutics (XLO) has 7 years of Free Cash Flow data on file, last reported at -$22.9 million in Q1 2026.
- For the quarter ending Q1 2026, Free Cash Flow fell 179.83% year-over-year to -$22.9 million; the trailing twelve-month figure through Mar 2026 stood at -$57.0 million (down 374.2% YoY), and the FY2025 full-year result was -$5.4 million, up 70.48% from the prior year.
- Free Cash Flow declined to -$22.9 million in Q1 2026, from -$2.0 million in the prior quarter.
- In the past five years, Free Cash Flow ranged from a high of $28.7 million in Q1 2025 to a low of -$25.4 million in Q1 2023.
- A 5-year average of -$11.3 million and a median of -$14.6 million in 2025 frame the typical range for Free Cash Flow.
- Across the five-year window, Free Cash Flow surged 372.6% in 2025 and tumbled 179.83% in 2026, its largest moves.
- Tracing XLO's Free Cash Flow over 5 years: stood at -$16.9 million in 2022, then climbed by 20.48% to -$13.4 million in 2023, then dropped by 5.48% to -$14.2 million in 2024, then soared by 85.75% to -$2.0 million in 2025, then sank by 1034.74% to -$22.9 million in 2026.
- Business Quant data shows XLO's Free Cash Flow at -$22.9 million in Q1 2026, -$2.0 million in Q4 2025, and -$17.5 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,621.14 Bn | 66,620.85 Bn | - | -19.58 Mn |
| 2 | Nanobiotix | 1,915.18 Bn | 1,915.11 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -2.49 Mn |
| 4 | BeOne Medicines | 471.27 Bn | 466.48 Bn | 1.35 Bn | 158.09 Mn |
| 5 | Vertex Pharmaceuticals | 121.81 Bn | 114.57 Bn | 2.59 Bn | 1.29 Bn |
| 6 | Regeneron Pharmaceuticals | 69.58 Bn | 60.82 Bn | 3.31 Bn | 848.30 Mn |
| 7 | Belite Bio | 62.72 Bn | 62.72 Bn | - | - |
| 8 | Argenx Se | 55.51 Bn | 50.33 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.35 Bn | 37.35 Bn | - | -354.95 Mn |
| 10 | Xilio Therapeutics | 148.60 Mn | -1.70 Mn | - | -22.90 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -22.90 Mn |
| Mar 31, 2026 | -22.90 Mn |
| Dec 31, 2025 | -2.02 Mn |
| Dec 31, 2025 | -2.02 Mn |
| Sep 30, 2025 | -17.50 Mn |
| Sep 30, 2025 | -17.50 Mn |
| Jun 30, 2025 | -14.61 Mn |
| Jun 30, 2025 | -14.61 Mn |
| Mar 31, 2025 | 28.69 Mn |
| Mar 31, 2025 | 28.69 Mn |
| Dec 31, 2024 | -14.16 Mn |
| Dec 31, 2024 | -14.16 Mn |
| Sep 30, 2024 | -13.68 Mn |
| Sep 30, 2024 | -13.68 Mn |
| Jun 30, 2024 | 19.95 Mn |
| Jun 30, 2024 | 19.95 Mn |
| Mar 31, 2024 | -10.52 Mn |
| Mar 31, 2024 | -10.52 Mn |
| Dec 31, 2023 | -13.43 Mn |
| Dec 31, 2023 | -13.43 Mn |