Xilio Therapeutics (XLO) Free Cash Flow (2020 - 2026)
Xilio Therapeutics' (XLO) quarterly Free Cash Flow came in at -$22.9 million in Q1 2026, down 179.83% year-on-year from $28.7 million in Q1 2025, and down 994.08% quarter-over-quarter from -$2.1 million in Q4 2025.
Xilio Therapeutics (XLO) Free Cash Flow (2020 - 2026) Analysis & Trends
Xilio Therapeutics has disclosed Free Cash Flow across 7 years of filings, most recently posting -$22.9 million for Q1 2026.
- Free Cash Flow for Q1 2026 came in at -$22.9 million, down 179.83% year-over-year; the trailing twelve-month figure through Mar 2026 was -$57.1 million (down 374.56% YoY), and the FY2025 annual result was -$5.5 million, up 70.08% from the prior year.
- Free Cash Flow came in at -$22.9 million for Q1 2026 at Xilio Therapeutics, down from -$2.1 million in the prior quarter.
- In the past five years, Free Cash Flow ranged from a high of $28.7 million in Q1 2025 to a low of -$25.4 million in Q1 2023.
- The 5-year median for Free Cash Flow is -$14.6 million (2025), against an average of -$11.3 million.
- Across the five-year window, Free Cash Flow surged 372.6% in 2025 and sank 179.83% in 2026, its largest moves.
- Xilio Therapeutics' Free Cash Flow stood at -$17.9 million in 2022, then increased by 24.87% to -$13.4 million in 2023, then declined by 5.48% to -$14.2 million in 2024, then surged by 85.22% to -$2.1 million in 2025, then sank by 994.08% to -$22.9 million in 2026.
- The last three Free Cash Flow figures came in at -$22.9 million (Q1 2026), -$2.1 million (Q4 2025), and -$17.5 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -1.67 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -12.20 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.49 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.29 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 63,220.27 |
| 10 | Xilio Therapeutics | 144.35 Mn | -5.95 Mn | - | -22.90 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -22.90 Mn |
| Mar 31, 2026 | -22.90 Mn |
| Dec 31, 2025 | -2.09 Mn |
| Dec 31, 2025 | -2.09 Mn |
| Sep 30, 2025 | -17.50 Mn |
| Sep 30, 2025 | -17.50 Mn |
| Jun 30, 2025 | -14.61 Mn |
| Jun 30, 2025 | -14.61 Mn |
| Mar 31, 2025 | 28.69 Mn |
| Mar 31, 2025 | 28.69 Mn |
| Dec 31, 2024 | -14.16 Mn |
| Dec 31, 2024 | -14.16 Mn |
| Sep 30, 2024 | -13.68 Mn |
| Sep 30, 2024 | -13.68 Mn |
| Jun 30, 2024 | 19.95 Mn |
| Jun 30, 2024 | 19.95 Mn |
| Mar 31, 2024 | -10.52 Mn |
| Mar 31, 2024 | -10.52 Mn |
| Dec 31, 2023 | -13.43 Mn |
| Dec 31, 2023 | -13.43 Mn |