Xilio Therapeutics (XLO) FCF Margin (2024 - 2026)
Xilio Therapeutics' (XLO) quarterly FCF Margin came in at 181.05% in Q1 2026, down 116009.0% year-on-year from N/an in Q1 2025, and down 1083.86% quarter-over-quarter from 15.29% in Q4 2025.
Xilio Therapeutics (XLO) FCF Margin (2024 - 2026) Analysis & Trends
Xilio Therapeutics has disclosed FCF Margin across 3 years of filings, most recently posting 181.05% for Q1 2026.
- FCF Margin for Q1 2026 came in at 181.05%, down 116009.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 106.75% (down 33098.0% YoY), and the FY2025 annual result was 12.59%, up 27767.0% from the prior year.
- FCF Margin came in at 181.05% for Q1 2026 at Xilio Therapeutics, down from 15.29% in the prior quarter.
- In the past five years, FCF Margin ranged from a high of 979.04% in Q1 2025 to a low of 821.52% in Q4 2024.
- The 3-year median for FCF Margin is 136.23% (2025), against an average of 8.66%.
- Across the five-year window, FCF Margin surged 80623 bps in 2025 and sank 116009 bps in 2026, its largest moves.
- Xilio Therapeutics' FCF Margin stood at 821.52% in 2024, then soared by 98 bps to 15.29% in 2025, then sank by 1084 bps to 181.05% in 2026.
- The last three FCF Margin figures came in at 181.05% (Q1 2026), 15.29% (Q4 2025), and 91.76% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -3.98% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 43.35% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Xilio Therapeutics | 144.35 Mn | -5.95 Mn | - | -181.05% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -181.05% |
| Dec 31, 2025 | -15.29% |
| Sep 30, 2025 | -91.76% |
| Jun 30, 2025 | -180.70% |
| Mar 31, 2025 | 979.04% |
| Dec 31, 2024 | -821.52% |
| Sep 30, 2024 | -604.55% |
| Jun 30, 2024 | 846.54% |