Xilio Therapeutics (XLO) FCF Margin (2024 - 2026)

Xilio Therapeutics' (XLO) quarterly FCF Margin came in at 181.05% in Q1 2026, down 116009.0% year-on-year from N/an in Q1 2025, and down 1083.86% quarter-over-quarter from 15.29% in Q4 2025.

Xilio Therapeutics (XLO) FCF Margin (2024 - 2026) Analysis & Trends

Xilio Therapeutics has disclosed FCF Margin across 3 years of filings, most recently posting 181.05% for Q1 2026.

  • FCF Margin for Q1 2026 came in at 181.05%, down 116009.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 106.75% (down 33098.0% YoY), and the FY2025 annual result was 12.59%, up 27767.0% from the prior year.
  • FCF Margin came in at 181.05% for Q1 2026 at Xilio Therapeutics, down from 15.29% in the prior quarter.
  • In the past five years, FCF Margin ranged from a high of 979.04% in Q1 2025 to a low of 821.52% in Q4 2024.
  • The 3-year median for FCF Margin is 136.23% (2025), against an average of 8.66%.
  • Across the five-year window, FCF Margin surged 80623 bps in 2025 and sank 116009 bps in 2026, its largest moves.
  • Xilio Therapeutics' FCF Margin stood at 821.52% in 2024, then soared by 98 bps to 15.29% in 2025, then sank by 1084 bps to 181.05% in 2026.
  • The last three FCF Margin figures came in at 181.05% (Q1 2026), 15.29% (Q4 2025), and 91.76% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -3.98%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 43.35%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Xilio Therapeutics 144.35 Mn -5.95 Mn - -181.05%

Historic Data

Download Data
DateValue
Mar 31, 2026 -181.05%
Dec 31, 2025 -15.29%
Sep 30, 2025 -91.76%
Jun 30, 2025 -180.70%
Mar 31, 2025 979.04%
Dec 31, 2024 -821.52%
Sep 30, 2024 -604.55%
Jun 30, 2024 846.54%