Xilio Therapeutics (XLO) FCF Margin (2024 - 2026)
Xilio Therapeutics (XLO) posted FCF Margin of 181.05% for Q1 2026, down 1127.86% sequentially from 14.74% in Q4 2025, and down 116009.0% YoY from N/an in Q1 2025.
Xilio Therapeutics (XLO) FCF Margin (2024 - 2026) Analysis & Trends
Xilio Therapeutics has reported FCF Margin for 3 years, with the latest figure at 181.05% in Q1 2026.
- Quarterly FCF Margin fell 116009.0% year-over-year to 181.05% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 106.61% (down 33084.0% YoY) and the FY2025 annual result came in at 12.42%, up 27784.0% from the prior year.
- FCF Margin fell to 181.05% in Q1 2026 per XLO's latest filing, from 14.74% in the prior quarter.
- Over five years, FCF Margin peaked at 979.04% in Q1 2025 and troughed at 821.52% in Q4 2024.
- A 3-year average of 8.59% and a median of 136.23% in 2025 frame the typical range for FCF Margin.
- The sharpest annual moves came in 2025 and 2026: FCF Margin soared 80677 bps in 2025, then sank 116009 bps in 2026.
- Over 3 years, FCF Margin stood at 821.52% in 2024, then jumped by 98 bps to 14.74% in 2025, then plunged by 1128 bps to 181.05% in 2026.
- According to Business Quant data, FCF Margin over the past three periods registered 181.05%, 14.74%, and 91.76% for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.69 Bn | 130.84 Bn | 2.84 Bn | 30.39% |
| 2 | Regeneron Pharmaceuticals | 86.29 Bn | 78.29 Bn | 3.93 Bn | 13.35% |
| 3 | Argenx Se | 64.79 Bn | 59.60 Bn | 1.37 Bn | - |
| 4 | Moderna | 59.44 Bn | 54.31 Bn | 52.00 Mn | -388.28% |
| 5 | BeOne Medicines | 42.07 Bn | 36.97 Bn | 1.53 Bn | 25.68% |
| 6 | Alnylam Pharmaceuticals | 30.92 Bn | 27.61 Bn | 992.69 Mn | 22.62% |
| 7 | BioNTech SE | 28.10 Bn | 9.71 Bn | 668.28 Mn | 41.07% |
| 8 | Insmed | 27.33 Bn | 26.17 Bn | 358.27 Mn | -22.35% |
| 9 | Royalty Pharma | 27.00 Bn | 26.17 Bn | - | 70.82% |
| 10 | Xilio Therapeutics | 177.07 Mn | 41.03 Mn | - | -100.48% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -100.48% |
| Mar 31, 2026 | -181.05% |
| Dec 31, 2025 | -14.74% |
| Sep 30, 2025 | -91.76% |
| Jun 30, 2025 | -180.70% |
| Mar 31, 2025 | 979.04% |
| Dec 31, 2024 | -821.52% |
| Sep 30, 2024 | -604.55% |
| Jun 30, 2024 | 846.54% |