Xilio Therapeutics (XLO) Enterprise Value (2020 - 2026)

Xilio Therapeutics' (XLO) quarterly Enterprise Value came in at -$150.3 million in Q1 2026, down 68.74% year-on-year from -$480.8 million in Q1 2025, and down 9.28% quarter-over-quarter from -$137.5 million in Q4 2025.

Xilio Therapeutics (XLO) Enterprise Value (2020 - 2026) Analysis & Trends

Xilio Therapeutics has disclosed Enterprise Value across 7 years of filings, most recently posting -$150.3 million for Q1 2026.

  • Enterprise Value for Q1 2026 came in at -$150.3 million, down 68.74% year-over-year; the trailing twelve-month figure through Mar 2026 was -$150.3 million (down 68.74% YoY), and the FY2025 annual result was -$137.5 million, down 148.74% from the prior year.
  • Enterprise Value came in at -$150.3 million for Q1 2026 at Xilio Therapeutics, down from -$137.5 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$34.0 million in Q1 2024 to a low of -$177.0 million in Q1 2022.
  • The 5-year median for Enterprise Value is -$93.3 million (2023), against an average of -$99.8 million.
  • Across the five-year window, Enterprise Value surged 63.57% in 2024 and plunged 162.13% in 2025, its largest moves.
  • Xilio Therapeutics' Enterprise Value stood at -$120.4 million in 2022, then surged by 62.87% to -$44.7 million in 2023, then declined by 23.68% to -$55.3 million in 2024, then slumped by 148.74% to -$137.5 million in 2025, then decreased by 9.28% to -$150.3 million in 2026.
  • The last three Enterprise Value figures came in at -$150.3 million (Q1 2026), -$137.5 million (Q4 2025), and -$103.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Xilio Therapeutics 144.35 Mn -5.95 Mn - -150.30 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -150.30 Mn
Dec 31, 2025 -137.53 Mn
Sep 30, 2025 -103.76 Mn
Jun 30, 2025 -121.55 Mn
Mar 31, 2025 -89.07 Mn
Dec 31, 2024 -55.29 Mn
Sep 30, 2024 -61.26 Mn
Jun 30, 2024 -74.95 Mn
Mar 31, 2024 -33.98 Mn
Dec 31, 2023 -44.70 Mn
Sep 30, 2023 -59.77 Mn
Jun 30, 2023 -75.38 Mn
Mar 31, 2023 -93.27 Mn
Dec 31, 2022 -120.39 Mn
Sep 30, 2022 -139.14 Mn
Jun 30, 2022 -159.41 Mn
Mar 31, 2022 -176.96 Mn
Dec 31, 2021 -198.05 Mn
Sep 30, 2021 -99.77 Mn
Jun 30, 2021 -120.30 Mn