Xilio Therapeutics (XLO) Enterprise Value (2020 - 2026)
Xilio Therapeutics' (XLO) quarterly Enterprise Value came in at -$150.3 million in Q1 2026, down 68.74% year-on-year from -$480.8 million in Q1 2025, and down 9.28% quarter-over-quarter from -$137.5 million in Q4 2025.
Xilio Therapeutics (XLO) Enterprise Value (2020 - 2026) Analysis & Trends
Xilio Therapeutics has disclosed Enterprise Value across 7 years of filings, most recently posting -$150.3 million for Q1 2026.
- Enterprise Value for Q1 2026 came in at -$150.3 million, down 68.74% year-over-year; the trailing twelve-month figure through Mar 2026 was -$150.3 million (down 68.74% YoY), and the FY2025 annual result was -$137.5 million, down 148.74% from the prior year.
- Enterprise Value came in at -$150.3 million for Q1 2026 at Xilio Therapeutics, down from -$137.5 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$34.0 million in Q1 2024 to a low of -$177.0 million in Q1 2022.
- The 5-year median for Enterprise Value is -$93.3 million (2023), against an average of -$99.8 million.
- Across the five-year window, Enterprise Value surged 63.57% in 2024 and plunged 162.13% in 2025, its largest moves.
- Xilio Therapeutics' Enterprise Value stood at -$120.4 million in 2022, then surged by 62.87% to -$44.7 million in 2023, then declined by 23.68% to -$55.3 million in 2024, then slumped by 148.74% to -$137.5 million in 2025, then decreased by 9.28% to -$150.3 million in 2026.
- The last three Enterprise Value figures came in at -$150.3 million (Q1 2026), -$137.5 million (Q4 2025), and -$103.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -18.44 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.77 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -584.73 Mn |
| 10 | Xilio Therapeutics | 144.35 Mn | -5.95 Mn | - | -150.30 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -150.30 Mn |
| Dec 31, 2025 | -137.53 Mn |
| Sep 30, 2025 | -103.76 Mn |
| Jun 30, 2025 | -121.55 Mn |
| Mar 31, 2025 | -89.07 Mn |
| Dec 31, 2024 | -55.29 Mn |
| Sep 30, 2024 | -61.26 Mn |
| Jun 30, 2024 | -74.95 Mn |
| Mar 31, 2024 | -33.98 Mn |
| Dec 31, 2023 | -44.70 Mn |
| Sep 30, 2023 | -59.77 Mn |
| Jun 30, 2023 | -75.38 Mn |
| Mar 31, 2023 | -93.27 Mn |
| Dec 31, 2022 | -120.39 Mn |
| Sep 30, 2022 | -139.14 Mn |
| Jun 30, 2022 | -159.41 Mn |
| Mar 31, 2022 | -176.96 Mn |
| Dec 31, 2021 | -198.05 Mn |
| Sep 30, 2021 | -99.77 Mn |
| Jun 30, 2021 | -120.30 Mn |