Xilio Therapeutics (XLO) EBITDA (2020 - 2026)
Xilio Therapeutics' (XLO) quarterly EBITDA came in at -$3.5 million in Q2 2026, up 75.7% year-over-year from -$2.0 million in Q2 2025, and up 75.26% quarter-over-quarter from -$14.1 million in Q1 2026.
Analysis
Xilio Therapeutics (XLO) EBITDA (2020 - 2026) Analysis & Trends
Xilio Therapeutics has disclosed EBITDA across 7 years of filings, most recently posting -$3.5 million for Q2 2026.
- In Q2 2026, EBITDA rose 75.7% year-over-year to -$3.5 million; the TTM figure through Jun 2026 stood at -$31.4 million (up 44.59% YoY), while the FY2025 annual figure was -$42.0 million, up 30.7% from the prior year.
- EBITDA came in at -$3.5 million for Q2 2026 at Xilio Therapeutics, up from -$14.1 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$1.9 million in Q3 2025 to a low of -$24.6 million in Q2 2022.
- Average EBITDA over 5 years is -$16.0 million, with a median of -$16.1 million recorded in 2023.
- Year-over-year, EBITDA slipped 28.47% in 2022 and soared 86.93% in 2025.
- Over 5 years, EBITDA stood at -$23.2 million in 2022, then grew by 21.74% to -$18.1 million in 2023, then rose by 24.83% to -$13.6 million in 2024, then rose by 13.16% to -$11.8 million in 2025, then jumped by 70.51% to -$3.5 million in 2026.
- Per Business Quant data, the three most recent EBITDA figures were -$3.5 million in Q2 2026, -$14.1 million in Q1 2026, and -$11.8 million in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 206.44 Bn | 192.45 Bn | 7.24 Bn | 3.51 Bn |
| 2 | Gilead Sciences | 179.97 Bn | 176.79 Bn | 6.22 Bn | -10.39 Bn |
| 3 | Vertex Pharmaceuticals | 130.57 Bn | 122.72 Bn | 2.84 Bn | 1.25 Bn |
| 4 | Regeneron Pharmaceuticals | 81.63 Bn | 73.63 Bn | 3.93 Bn | 1.29 Bn |
| 5 | Argenx Se | 60.34 Bn | 55.16 Bn | 1.37 Bn | 493.00 Mn |
| 6 | Moderna | 54.37 Bn | 49.23 Bn | 52.00 Mn | -815.00 Mn |
| 7 | Alnylam Pharmaceuticals | 33.07 Bn | 29.76 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Biogen | 31.84 Bn | 30.55 Bn | 1.96 Bn | -644.50 Mn |
| 9 | Roivant Sciences | 29.49 Bn | 29.49 Bn | 1.16 Mn | -365.99 Mn |
| 10 | Xilio Therapeutics | 174.55 Mn | 38.51 Mn | - | -3.49 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3.49 Mn |
| Mar 31, 2026 | -14.11 Mn |
| Dec 31, 2025 | -11.84 Mn |
| Sep 30, 2025 | -1.93 Mn |
| Jun 30, 2025 | -14.37 Mn |
| Mar 31, 2025 | -13.85 Mn |
| Dec 31, 2024 | -13.63 Mn |
| Sep 30, 2024 | -14.76 Mn |
| Jun 30, 2024 | -14.70 Mn |
| Mar 31, 2024 | -17.49 Mn |
| Dec 31, 2023 | -18.13 Mn |
| Sep 30, 2023 | -17.36 Mn |
| Jun 30, 2023 | -20.12 Mn |
| Mar 31, 2023 | -23.53 Mn |
| Dec 31, 2022 | -23.17 Mn |
| Sep 30, 2022 | -20.21 Mn |
| Jun 30, 2022 | -24.55 Mn |
| Mar 31, 2022 | -21.22 Mn |
| Dec 31, 2021 | -19.56 Mn |
| Sep 30, 2021 | -15.96 Mn |